Browsing Articles publicats (IRBLleida) by Title
Now showing items 794-813 of 1060
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Proposal for the creation of a national strategy for precision medicine in cancer: a position statement of SEOM, SEAP and SEFH
(Aula Médica Ediciones, 2017)Precision medicine is an emerging approach for disease treatment and prevention that takes into account individual variability in genes, environment, and lifestyle for each person. Precision medicine is transforming ... -
Proposal for the creation of a national strategy for precision medicine in cancer: a position statement of SEOM, SEAP,and SEFH
(Springer, 2018)Precision medicine is an emerging approach for disease treatment and prevention that takes into account individual variability in genes, environment, and lifestyle for each person. Precision medicine is transforming ... -
Prostate-targeted radiosensitization via aptamer-shRNA chimeras in human tumor xenografts
(American Society for Clinical Investigation, 2011)Dose-escalated radiation therapy for localized prostate cancer (PCa) has a clear therapeutic benefit; however, escalated doses may also increase injury to noncancerous tissues. Radiosensitizing agents can improve ... -
Protective role of renal proximal tubular alpha-synuclein in the pathogenesis of kidney fibrosis
(Nature Publishing Group, 2020)Kidney fibrosis is a highly deleterious process and a final manifestation of chronic kidney disease. Alpha-(α)-synuclein (SNCA) is an actin-binding neuronal protein with various functions within the brain; however, its ... -
Protein carbonylation: proteomics, specificity and relevance to aging
(Wiley, 2013)Detection and quantification of protein carbonyls present in biological samples has become a popular, albeit indirect, method to determine the existence of oxidative stress. Moreover, the rise of proteomics has allowed ... -
Protein Kinase KIS Localizes to RNA Granules and Enhances Local Translation
(American Society for Microbiology, 2009)The regulation of mRNA transport is a fundamental process for cytoplasmic sorting of transcripts and spatially controlled translational derepression once properly localized. There is growing evidence that translation is ... -
Protein oxidation in Huntington disease
(Wiley, 2012-05)Huntington disease (HD) is an inherited neurodegenerative disorder caused by expansion of CAG repeats in the huntingtin gene, affecting initially the striatum and progressively the cortex. Oxidative stress, and consequent ... -
Protein oxidation in Huntington disease affects energy production and vitamin B6 metabolism
(Elsevier, 2010)Huntington disease (HD) is an inherited neurodegenerative disorder that initially affects the striatum and progressively the cortex. Oxidative stress in HD has been described as important to disease progression. In ... -
Protein targets of oxidative damage in human neurodegenerative diseases with abnormal protein aggregates
(Wiley, 2010)Human neurodegenerative diseases with abnormal protein aggregates are associated with aberrant post-translational modifications, solubility, aggregation and fibril formation of selected proteins which cannot be degraded ... -
Proteins in human brain cortex are modified by oxidation, glycoxidation and lipoxidation: effects of Alzheimer's disease and identification of lipoxidation targets.
(American Society for Biochemistry and Molecular Biology; Elsevier, 2005)Diverse oxidative pathways, such as direct oxidation of amino acids, glycoxidation, and lipoxidation could contribute to Alzheimer disease pathogenesis. A global survey for the amount of structurally characterized probes ... -
Proteomic and oxidative stress analysis in human brain samples of Huntington disease
(Elsevier, 2008)Huntington disease (HD) is a neurodegenerative disorder caused by expansion of CAG repeats in exon 1 of the huntingtin gene, affecting initially the striatum and progressively the cortex. This work reports a proteomic analysis ... -
Pseudophakic cystoid macular edema: update 2016
(Dovepress, 2016)Pseudophakic cystoid macular edema (PCME) is the most common complication of cataract surgery, leading in some cases to a decrease in vision. Although the pathogenesis of PCME is not completely understood, the contribution ... -
Psoriasis, metabolic syndrome and cardiovascular risk factors. A population-based study.
(Wiley, 2019)Abstract Background: Psoriasis is a very prevalent systemic chronic inflammatory disease. Major cardiovascular events are the main cause of mortality in these patients which suggests an association between psoriasis and ... -
Psychological Well-Being in Nursing Students: A Multicentric, Cross-Sectional Study
(MDPI, 2021-03-15)In addition to complying with strict academic standards, nursing students must acquire relevant knowledge and skills, and learn how to carry themselves in different and often stressful professional settings. These obligations ... -
Psychometric properties of the Catalan version of DS14 scale for assessing Type-D personality
(Universitat de Barcelona; Elsevier, 2018)This study was designed to check the psychometric properties of an online Catalan version of the Type D Personality Scale-14 (DS14). Participants were 600 subjects including university professors, service and administrative ... -
Psychometric properties of the Catalan version of the Trait Emotional Intelligence (TEIQue): Comparison between Catalan and English data
(Elsevier, 2016-05-18)The present study compared the psychometric properties of the Trait Emotional Intelligence Questionnaire (TEIQue) in Catalan and UK samples. The results showed similar means and standard deviations in the facets scoring ... -
Psychometric properties of the SDM-Q-9 questionnaire for shared decision-making in multiple sclerosis: item response theory modelling and confirmatory factor analysis
(BioMed Central, 2017)Background: Shared decision-making is a cornerstone of patient-centred care. The 9-item Shared Decision-Making Questionnaire (SDM-Q-9) is a brief self-assessment tool for measuring patients’ perceived level of involvement ... -
Psychometric Properties of the SymptoMScreen Questionnaire in a Mild Disability Population of Patients with Relapsing–Remitting Multiple Sclerosis: Quantifying the Patient’s Perspective
(Springer, 2020)Crucial elements for achieving optimal long-term outcomes in multiple sclerosis (MS) are patient confidence and effective physician-patient communication. Patient-reported instruments may provide the means to fill the gap ... -
Psychosocial work dimensions, personality, and body mass index: sex differences
(Nofer Institute of Occupational Medicine, 2013)Objectives: The association between psychosocial work dimensions (i.e. demand and control) and obesity has been found to be inconclusive, indicating that individual differences factors might also contribute to explain the ... -
Pterygium surgery by means of conjunctival autograft: long term follow-up
(Conselho Brasileiro de Oftalmologia, 2012)PURPOSE: To demonstrate the long term of follow-up of the recurrence rate after conjunctival autograft for pterygium surgery. METHODS: A total of 112 patients operated for pterygium with conjunctival autografts and with ...