Browsing Articles publicats (IRBLleida) by Title
Now showing items 789-808 of 1060
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proBDNF is modified by advanced glycation end products in Alzheimer’s disease and causes neuronal apoptosis by inducing p75 neurotrophin receptor processing
(BMC, 2018)Alzheimer disease (AD) is a complex pathology related to multiple causes including oxidative stress. Brain-derived neurotrophic factor (BDNF) is a neutrotrophic factor essential for the survival and differentiation of ... -
Productos finales de glicación avanzada en la obesidad mórbida y tras la cirugía bariátrica: cuando la memoria glucémica empieza a fallar
(Elsevier España, 2017-01-18)Antecedentes y objetivo: Los productos finales de glicación avanzada (AGE) son un indicador de memoria metabólica. Su concentración se incrementa cuando existe estrés oxidativo, inflamación o hiperglucemia crónica. Se ... -
Profiles of Motor Laterality in Young Athletes' Performance of Complex Movements: Merging the MOTORLAT and PATHoops Tools
(Frontiers Media, 2018)Laterality is a key aspect of the analysis of basic and specific motor skills. It is relevant to sports because it involves motor laterality profiles beyond left-right preference and spatial orientation of the body. The ... -
Prognostic value of symptoms at lung cancer diagnosis: a three-year observational study
(AME Publishing, 2021-03)Background: Lung cancer is mainly diagnosed at advanced or locally advanced stages, usually when symptoms become evident. However, sometimes it may be diagnosed incidentally during routine care, while patients are still ... -
Prokaryotic and eukaryotic monothiol glutaredoxins are able to perform the functions of Grx5 in the biogenesis of Fe/S clusters in yeast mitochondria
(Elsevier, 2003)The Saccharomyces cerevisiae monothiol glutare- doxin Grx5 participates in the mitochondrial biogenesis of iron–sulfur clusters. Grx5 homologues exist in organisms from bacteria to humans. Chicken (cGRX5) and human ... -
Proposal for the creation of a national strategy for precision medicine in cancer: a position statement of SEOM, SEAP and SEFH
(Aula Médica Ediciones, 2017)Precision medicine is an emerging approach for disease treatment and prevention that takes into account individual variability in genes, environment, and lifestyle for each person. Precision medicine is transforming ... -
Proposal for the creation of a national strategy for precision medicine in cancer: a position statement of SEOM, SEAP,and SEFH
(Springer, 2018)Precision medicine is an emerging approach for disease treatment and prevention that takes into account individual variability in genes, environment, and lifestyle for each person. Precision medicine is transforming ... -
Prostate-targeted radiosensitization via aptamer-shRNA chimeras in human tumor xenografts
(American Society for Clinical Investigation, 2011)Dose-escalated radiation therapy for localized prostate cancer (PCa) has a clear therapeutic benefit; however, escalated doses may also increase injury to noncancerous tissues. Radiosensitizing agents can improve ... -
Protective role of renal proximal tubular alpha-synuclein in the pathogenesis of kidney fibrosis
(Nature Publishing Group, 2020)Kidney fibrosis is a highly deleterious process and a final manifestation of chronic kidney disease. Alpha-(α)-synuclein (SNCA) is an actin-binding neuronal protein with various functions within the brain; however, its ... -
Protein carbonylation: proteomics, specificity and relevance to aging
(Wiley, 2013)Detection and quantification of protein carbonyls present in biological samples has become a popular, albeit indirect, method to determine the existence of oxidative stress. Moreover, the rise of proteomics has allowed ... -
Protein Kinase KIS Localizes to RNA Granules and Enhances Local Translation
(American Society for Microbiology, 2009)The regulation of mRNA transport is a fundamental process for cytoplasmic sorting of transcripts and spatially controlled translational derepression once properly localized. There is growing evidence that translation is ... -
Protein oxidation in Huntington disease
(Wiley, 2012-05)Huntington disease (HD) is an inherited neurodegenerative disorder caused by expansion of CAG repeats in the huntingtin gene, affecting initially the striatum and progressively the cortex. Oxidative stress, and consequent ... -
Protein oxidation in Huntington disease affects energy production and vitamin B6 metabolism
(Elsevier, 2010)Huntington disease (HD) is an inherited neurodegenerative disorder that initially affects the striatum and progressively the cortex. Oxidative stress in HD has been described as important to disease progression. In ... -
Protein targets of oxidative damage in human neurodegenerative diseases with abnormal protein aggregates
(Wiley, 2010)Human neurodegenerative diseases with abnormal protein aggregates are associated with aberrant post-translational modifications, solubility, aggregation and fibril formation of selected proteins which cannot be degraded ... -
Proteins in human brain cortex are modified by oxidation, glycoxidation and lipoxidation: effects of Alzheimer's disease and identification of lipoxidation targets.
(American Society for Biochemistry and Molecular Biology; Elsevier, 2005)Diverse oxidative pathways, such as direct oxidation of amino acids, glycoxidation, and lipoxidation could contribute to Alzheimer disease pathogenesis. A global survey for the amount of structurally characterized probes ... -
Proteomic and oxidative stress analysis in human brain samples of Huntington disease
(Elsevier, 2008)Huntington disease (HD) is a neurodegenerative disorder caused by expansion of CAG repeats in exon 1 of the huntingtin gene, affecting initially the striatum and progressively the cortex. This work reports a proteomic analysis ... -
Pseudophakic cystoid macular edema: update 2016
(Dovepress, 2016)Pseudophakic cystoid macular edema (PCME) is the most common complication of cataract surgery, leading in some cases to a decrease in vision. Although the pathogenesis of PCME is not completely understood, the contribution ... -
Psoriasis, metabolic syndrome and cardiovascular risk factors. A population-based study.
(Wiley, 2019)Abstract Background: Psoriasis is a very prevalent systemic chronic inflammatory disease. Major cardiovascular events are the main cause of mortality in these patients which suggests an association between psoriasis and ... -
Psychological Well-Being in Nursing Students: A Multicentric, Cross-Sectional Study
(MDPI, 2021-03-15)In addition to complying with strict academic standards, nursing students must acquire relevant knowledge and skills, and learn how to carry themselves in different and often stressful professional settings. These obligations ... -
Psychometric properties of the Catalan version of DS14 scale for assessing Type-D personality
(Universitat de Barcelona; Elsevier, 2018)This study was designed to check the psychometric properties of an online Catalan version of the Type D Personality Scale-14 (DS14). Participants were 600 subjects including university professors, service and administrative ...