Now showing items 759-778 of 906

    • Spanish People with Type 2 Diabetes Show an Improved Adherence to the Mediterranean Diet 

      Alcubierre Calvo, Núria; Granado Casas, Minerva; Real, Jordi; Perpiñán, Hèctor; Rubinat, Esther; Falguera, Mireia; Castelblanco Echavarría, Esmeralda; Franch-Nadal, Josep; Mauricio Puente, Dídac (MDPI, 2020)
      The aim of this study was to assess the dietary pattern (i.e., Mediterranean Diet (MedDiet) and healthy eating) in people with type 2 diabetes (T2D) compared with those without diabetes. In addition, we explored clinical ...
    • Spanish-dementia knowledge assessment scale (DKAS-S): psychometric properties and validation 

      Carnes Vendrell, Anna; Barallat Gimeno, Eva; Galvan, Ana; Lara Gallego, Beatriz; Lladó, Albert; Contador-Muñana, Jose; Vega Rodríguez, Angela; Escobar Bravo, Miguel Ángel; Piñol Ripoll, Gerard (BioMed Central, 2021-05-01)
      Background Alzheimer's disease (AD) is the most frequent cause of cognitive impairment. Community knowledge of the disease has proven to be a very important aspect of the development of interventions and the evaluation of ...
    • Special Issue "Diabetic Nephropathy: Diagnosis, Prevention and Treatment" 

      Ruiz Ortega, Marta; Rodrigues-Diez, Raul; Lavoz, Carolina; Rayego Mateos, Sandra (MDPI, 2020)
      Diabetic nephropathy (DN) is the main cause of end-stage renal disease. DN is a complex disease mediated by genetic and environmental factors, and many cellular and molecular mechanisms are involved in renal damage in ...
    • Specific Metabolomics Adaptations Define a Differential Regional Vulnerability in the Adult Human Cerebral Cortex 

      Cabré Cucó, Rosanna; Jové Font, Mariona; Naudí i Farré, Alba; Ayala Jové, Ma. Victoria (Maria Victoria); Piñol Ripoll, Gerard; Gil Villar, M. Pilar; Dominguez Gonzalez, Mayelin; Obis Monné, Èlia; Berdun, Rebeca; Mota Martorell, Natàlia; Portero Otín, Manuel; Ferrer, Isidre; Pamplona Gras, Reinald (Frontiers in Molecular Neurosciencie, 2016)
      Brain neurons offer diverse responses to stresses and detrimental factors during development and aging, and as a result of both neurodegenerative and neuropsychiatric disorders. This multiplicity of responses can be ascribed ...
    • Spindle-independent condensation-mediated segregation of yeast ribosomal DNA in late anaphase 

      Machín, Félix; Torres Rosell, Jordi; Jarmuz, Adam; Aragón, Luis (The Rockefeller University Press, 2005)
      Mitotic cell division involves the equal segregation of all chromosomes during anaphase. The presence of ribosomal DNA (rDNA) repeats on the right arm of chromosome XII makes it the longest in the budding yeast genome. ...
    • Sprouty1 controls genitourinary development via its N-terminal tyrosine 

      Vaquero, Marta; Cuesta, Sara; Anerillas, Carlos; Altés, Gisela; Ribera i Calvet, Joan; Basson, M. Albert; Licht, Jonathan D.; Egea Navarro, Joaquim; Encinas Martín, Mario (American Society of Nephrology, 2019-08-01)
      Background: Congenital anomalies of the kidney and urinary tract (CAKUT) is a group of diseases that include a broad spectrum of developmental defects of the genitourinary system. Mouse models indicate that perturbations ...
    • Sprouty1 haploinsufficiency accelerates pheochromocytoma development in Pten+/- mice 

      Vaquero, Marta; Macià Armengol, Anna; Anerillas Aljama, Diego; Velasco Sánchez, Ana; Matias-Guiu, Xavier; Ribera i Calvet, Joan; Encinas Martín, Mario (Society for Endocrinology, 2016-02-01)
      Pheochromocytomas (PCCs) are rare catecholamine-secreting tumors arising from the chromaffin cells in the adrenal medulla. Closely related paragangliomas share developmental origin but arise extra-adrenally, in the paraganglia ...
    • Statins do not increase markers of cerebral angiopathies in patients with cardioembolic stroke 

      Martí Fàbregas, Joan; Medrano-Martorell, Santiago; Merino, Elisa; Prats Sánchez, Luis; Marín, Rebeca; Delgado Mederos, Raquel; Camps Renom, Pol; Martínez Domeño, Alejandro; Gómez Choco, Manuel; Lara, Lidia; Casado-Naranjo, Ignacio; Cánovas, David; Torres, Maria José; Freijo, María del Mar; Calleja, Ana; Bravo, Yolanda; Cocho, Dolores; Rodríguez-Campello, Ana; Zandio, Beatriz; Fuentes, Blanca; Felipe, Alicia de; Llull, Laura; Maestre, José; Hernández, María; Garcés, Moisés; Arce-Borda, Ana Maria de; Palomeras, Ernest; Rodríguez-Yáñez, Manuel; Díaz-Maroto, Inma; Serrano, Marta; Fernández-Domínguez, Jéssica; Sanahuja Montesinos, Jordi; Purroy Garcia, Francisco; Zedde, Marialuisa; Delgado-Mengual, Jordi; Gich, Ignasi (Nature Publishing Group, 2018)
      We investigated whether pre-treatment with statins is associated with surrogate markers of amyloid and hypertensive angiopathies in patients who need to start long-term oral anticoagulation therapy. A prospective multicenter ...
    • Steady-state global optimization of metabolic non-linear dynamic models through recasting into power-law canonical models 

      Pozo Fernández, Carlos; Marín-Sanguino, Alberto; Alves, Rui; Guillén Gosálbez, Gonzalo; Jiménez Esteller, Laureano; Sorribas Tello, Albert (BioMed Central, 2011)
      Background: Design of newly engineered microbial strains for biotechnological purposes would greatly benefit from the development of realistic mathematical models for the processes to be optimized. Such models can then be ...
    • Stratification of the severity of critically ill patients with classification trees 

      Trujillano Cabello, Javier; Badia Castello, Mariona; Servià Goixart, Lluís; March Llanes, Jaume; Rodríguez Pozo, Ángel (BioMed Central, 2009)
      Background: Development of three classification trees (CT) based on the CART (Classification and Regression Trees), CHAID (Chi-Square Automatic Interaction Detection) and C4.5 methodologies for the calculation of probability ...
    • Structural analysis of the facets and domains of the Zuckerman–Kuhlman–Aluja Personality Questionnaire (ZKA–PQ) and the NEO PI–R 

      Aluja Fabregat, Antón; Blanch Plana, Angel; García, Oscar; Escorial, Sergio; García Rodríguez, Luis Francisco (Taylor & Francis Group, 2012)
      Aluja, Kuhlman, and Zuckerman (2010) developed an instrument for American and Spanish populations (Zuckerman–Kuhlman–Aluja Personality Questionnaire [ZKA–PQ]) that includes 4 facets for each 5 basic traits of Zuckerman’s ...
    • Structural and functional diversity of glutaredoxins in yeast 

      Herrero Perpiñán, Enrique; Bellí i Martínez, Gemma; Casas Herranz, Celia (Bentham Science Publishers, 2010)
      Glutaredoxins are defined as thiol disulfide oxidoreductases that reduce disulfide bonds employing reduced glutathione as electron donor. They constitute a complex family of proteins with a diversity of enzymatic and ...
    • Structure-function analysis of yeast Grx5 monothiol glutaredoxin defines essential amino acids for the function of the protein 

      Bellí i Martínez, Gemma; Polaina, Julio; Tamarit Sumalla, Jordi; Torre Ruiz, M. A. de la; Rodríguez Manzanaque, Maria Teresa; Ros Salvador, Joaquim; Herrero Perpiñán, Enrique (The American Society for Biochemistry and Molecular Biology, 2002)
      Grx5 defines a family of yeast monothiol glutaredox- ins that also includes Grx3 and Grx4. All three proteins display significant sequence homology with proteins found from bacteria to humans. Grx5 is involved in ...
    • Study of community-living Alzheimer’s patients’ adherence to the Mediterranean diet and risks of malnutrition at different disease stages 

      Rocaspana-Garcia, Mariona; Blanco Blanco, Joan; Arias-Pastor, Alfonso; Gea Sánchez, Montserrat; Piñol Ripoll, Gerard (PeerJ, 2018)
      Alzheimer’s disease (AD) is a neurodegenerative disease that is characterized by deficits in episodic memory. It is the most common form of dementia and affects 50–70% of patients with cognitive impairments over the age ...
    • Subcutaneous advanced glycation end-products and lung function according to glucose abnormalities: The ILERVAS project 

      Sánchez Peña, Enric; Lecube Torelló, Albert; Betriu i Bars, M. Àngels; Hernández, Cristina; López Cano, Carolina; Gutiérrez Carrasquilla, Liliana; Kerkeni, M.; Yeramian Hakim, Andree; Purroy Garcia, Francisco; Pamplona Gras, Reinald; Farràs-Sallés, Cristina; Fernández i Giráldez, Elvira; Barbé Illa, Ferran; Simó, Rafael (Elsevier, 2019-12-01)
    • Subdivisions and derivatives of the chicken subpallium based on expression of LIM and other regulatory genes and markers of neuron subpopulations during development 

      Abellán Ródenas, Antonio; Medina Hernández, Loreta Mª (Wiley, 2009)
      Here we studied the combinatory expression patterns of nine developmental regulatory genes and six markers of different neuronal subpopulations in the telencephalic subpallium of developing chicken, from early embryos ...
    • Succination of protein thiols in human brain aging 

      Jové Font, Mariona; Pradas Barriga, Irene; Mota Martorell, Natàlia; Cabré Cucó, Rosanna; Ayala Jové, Ma. Victoria (Maria Victoria); Ferrer, Isidre; Pamplona Gras, Reinald (Frontiers Media, 2020-03-06)
      Human brain evolution toward complexity has been achieved with increasing energy supply as the main adaptation in brain metabolism. Energy metabolism, like other biochemical reactions in aerobic cells, is under enzymatic ...
    • Suicide, the main cause of referral of patients from a general hospital for psychiatric evaluation 

      Gómez, Elena; Guzmán, Marianela; Yuguero Torres, Oriol (Heighten Science Publications Corporation (HSPC), 2021)
      Introduction: Psychiatric emergencies constitute between 1% - 10% of general emergencies in Spain, of which a quarter will end up being hospital admissions. There is little literature on patients who are referred from ...
    • Sumoylation of Smc5 Promotes Error-free Bypass at Damaged Replication Forks 

      Zapatka, Mariel; Pociño Merino, Irene; Heluani-Gahete, Hayat; Bermúdez López, Marcelino; Tarrés, Marc; Ibars Estiarte, Eva Irene; Solé-Soler, Roger; Gutiérrez-Escribano, Pilar; Apostolova, Sonia; Casas Herranz, Celia; Aragon, Luis; Wellinger, Ralf Erik; Colomina i Gabarrella, Neus; Torres Rosell, Jordi (Elsevier, 2019)
      Replication of a damaged DNA template can threaten the integrity of the genome, requiring the use of various mechanisms to tolerate DNA lesions. The Smc5/6 complex, together with the Nse2/Mms21 SUMO ligase, plays essential ...
    • Surgical dynamometer to simultaneously measure the tension forces and the distance between wound edges during the closure of a laparotomy 

      Roca Enrich, Joan; Nogués Aymamí, Miquel; Villalobos Mori, Rafael; Mias Carballal, Mª Carmen; Comellas Andrés, Martí; Gas Ruiz, Cristina; Olsina Kissler, Jorge Juan (MDPI, 2018)
      The closure of the abdominal wall after making a laparotomy is a major challenge for surgeons, since a significant percentage of closures fail and incisional hernias rise. The suture has to withstand the forces required ...