Now showing items 724-743 of 934

    • Regulation of membrane unsaturation as antioxidant adaptive mechanism in long-lived animal species 

      Naudí i Farré, Alba; Jové Font, Mariona; Ayala Jové, Ma. Victoria (Maria Victoria); Portero Otín, Manuel; Barja, Gustavo; Pamplona Gras, Reinald (Phcog.Net, 2011)
      Oxidative stress resulting from biomolecular oxidative damage due to the imbalance between reactive species production and antioxidant response has become an universal constraint of life-history evolution in animals and ...
    • Regulation of small GTPase activity by G1 cyclins 

      Pedraza González, Neus; Cemeli, Tània; Monserrat Monserrat, Maria Ventura; Garí Marsol, Eloi; Ferrezuelo, Francisco (Taylor & Francis, 2017-01-27)
      Together with a cyclin-dependent kinase (CDK) partner G1 cyclins control cell cycle entry by phosphorylating a number of nuclear targets and releasing a transcriptional program at the end of G1 phase. Yeast G1 cyclins also ...
    • Regulation of survival motor neuron protein by the nuclear factor-kappa B pathway in mouse spinal cord motoneurons 

      Arumugam, Saravanan; Tasheva, Stefka Mincheva; Periyakaruppiah, Ambika; Fuente Ruiz, Sandra de la; Soler i Tatché, Rosa Ma.; Garcera, Ana (Springer Verlag, 2017-08-14)
      Survival motor neuron (SMN) protein deficiency causes the genetic neuromuscular disorder spinal muscular atrophy (SMA), characterized by spinal cord motoneuron degeneration. Since SMN protein level is critical to disease ...
    • Regulation of the cell integrity pathway by rapamycin-sensitive TOR function in budding yeast 

      Torres Rosell, Jordi; Di Como, Charles J.; Herrero Perpiñán, Enrique; Torre Ruiz, M. A. de la (The American Society for Biochemistry and Molecular Biology, 2002)
      The TOR (target of rapamycin) pathway controls cell growth in response to nutrient availability in eukary- otic cells. Inactivation of TOR function by rapamycin or nutrient exhaustion is accompanied by triggering various ...
    • Regulation of the Na+/K+-ATPase Ena1 Expression by Calcineurin/Crz1 under High pH Stress: a quantitative study 

      Petrezsélyová, Silvia; López Malo, María; Canadell, David; Roque, Alicia; Serra Cardona, Albert; Marqués, M. Carmen; Vilaprinyo Terré, Ester; Alves, Rui; Yenush, Lynne; Ariño Carmona, Joaquín (Public Library of Science, 2016)
      Regulated expression of the Ena1 Na+-ATPase is a crucial event for adaptation to high salt and/or alkaline pH stress in the budding yeast Saccharomyces cerevisiae. ENA1 expression is under the control of diverse signaling ...
    • Relationship between aldosterone and the metabolic syndrome in patients with obstructive sleep apnea hypopnea syndrome: effect of continuous positive airway pressure treatment 

      Barceló Bennasar, Antònia; Piérola, Javier; Esquinas López, Cristina; Peña, Mónica de la; Arqué, Meritxell; Alonso-Fernández, Alberto; Bauçà, Josep Miquel; Robles, Juan; Barceló, Bernardino; Barbé Illa, Ferran (Public Library of Science, 2014)
      Methods: We studied 66 patients with OSAHS (33 with MS and 33 without MS) and 35 controls. The occurrence of the MS was analyzed according to the National Cholesterol Education Program Adult Treatment Panel III (NCEP ATP ...
    • Relationship between empathy and the big five personality traits in a sample of Spanish adolescents 

      Barrio, María Victoria del; Aluja Fabregat, Antón; García Rodríguez, Luis Francisco (Society for Personality Research, 2004)
      Empathy has been considered a central feature of our temperamental dispositions in childhood and adolescence. It plays a central role in the development of prosocial behavior and moral reasoning. However, the links between ...
    • Relationship between low levels of circulating TRAIL and atheromatosis progression in patients with chronic kidney disease. 

      Arcidiacono, Maria V.; Rimondi, Erika; Maietti, Elisa; Melloni, Elisabetta; Tisato, Veronica; Gallo, Stefania; Valdivielso Revilla, José Manuel; Fernández i Giráldez, Elvira; Betriu i Bars, M. Àngels; Voltan, Rebecca; Zauli, Giorgio; Volpato, Stefano; Secchiero, Paola (Public Library of Science, 2018-09-11)
      Background: Chronic kidney disease (CKD) patients experience a high risk of cardiovascular disease (CV); however, the factors involved in CV-related morbidity and mortality in these patients have not been fully defined. ...
    • Relationship of the adherence to the Mediterranean diet with health-related quality of life and treatment satisfaction in patients with type 2 diabetes mellitus: a post-hoc analysis of a cross-sectional study 

      Alcubierre Calvo, Núria; Martínez Alonso, Montserrat; Valls Marsal, Joan; Rubinat, Esther; Traveset Maeso, Alicia; Hernandez, Marta; Martínez González, María Dolores; Granado Casas, Minerva; Jurjo Campo, Carmen; Vioque, Jesus; Navarrete Muñoz, Eva María; Mauricio Puente, Dídac (BioMed Central, 2016)
      Objective: The main aim of this study was to assess the association between adherence to the traditional Mediterranean diet (MedDiet) and health-related quality of life (HRQoL) and treatment satisfaction in patients ...
    • Relationships between big five personality factors and values 

      Aluja Fabregat, Antón; García Rodríguez, Luis Francisco (Society for Personality Research, 2004)
      An analysis of principal components showed a robust structure of three factors formed by 25 of the 30 values studied. These factors were called Social Power, Order and Benevolence values. Those factors match with some ...
    • Relative amino acid composition signatures of organisms and environments 

      Moura, Alexandra; Savageau, Michael A.; Alves, Rui (Public Library of Science, 2013)
      Background: Identifying organism-environment interactions at the molecular level is crucial to understanding how organisms adapt to and change the chemical and molecular landscape of their habitats. In this work we ...
    • REMOTE ischemic perconditioning among acute ischemic stroke patients in Catalonia: REMOTE-CAT PROJECT 

      Purroy Garcia, Francisco; Arque, Gloria; Mauri-Capdevila, Gerard; García-Vázquez, Cristina; Vicente-Pascual, Mikel; Pereira, Cristina; Vazquez-Justes, Daniel; Torres-Querol, Coral; Vena Martínez, Ana Belén; Abilleira, Sònia; Cardona, Pere; Forné Izquierdo, Carles; Jiménez-Fàbrega, Xavier; Pagola, Jorge; Portero Otín, Manuel; Rodríguez-Campello, Ana; Rovira, Àlex; Fàbregas, Joan Martí (Frontiers Media, 2020)
      Rationale: Remote ischemic perconditioning during cerebral ischemia (RIPerC) refers to the application of brief episodes of transient limb ischemia commonly to a limb, it represents a new safe, simple and low-cost paradigm ...
    • Reporting of methodologic information on trial registries for quality assessment: a study of trial records retrieved from the WHO search portal 

      Reveiz, Ludovic; Chan, An-Wen; Krleza-Jeric, Karmela; Granados, Carlos Eduardo; Pinart, Mariona; Etxeandia, Itziar; Rada, Diego; Martínez Alonso, Montserrat; Bonfill, Xavier; Cardona, Andrés Felipe (Public Library of Science (PLoS), 2010)
      Background: Although randomized clinical trials (RCTs) are considered the gold standard of evidence, their reporting is often suboptimal. Trial registries have the potential to contribute important methodologic information ...
    • Reproducibility of measurement of myometrial invasion in endometrial carcinoma 

      van der Putten, Louis J. M.; van de Vijver, Koen; Bartosch, Carla; Davidson, Ben; Gatius Calderó, Sònia; Matias-Guiu, Xavier; McCluggage, W. Glenn; Toledo, Gemma; van der Wurff, Anneke A. M.; Pijnenborg, Johanna M. A.; Massuger, Leon F. A. G.; Bulten, Johan (Springer Berlin Heidelberg, 2016)
      Myometrial invasion (MI) as a percentage (%MI), categorized into <50 or ≥50 %, is an important predictor of prognosis in endometrial carcinoma. Recent studies suggest that tumor-free distance (TFD) to serosa and the absolute ...
    • Repurposed Analog of GLP-1 Ameliorates Hyperglycemia in Type 1 Diabetic Mice Through Pancreatic Cell Reprogramming 

      Villalba, Adrian; Rodríguez Fernández, Silvia; Perna Barrull, David; Ampudia, Rosa Maria; Gómez Muñoz, Laia; Pujol Autonell, Irma; Aguilera, Eva; Coma, Mireia; Cano Sarabia, Antonia María; Vázquez, Federico; Verdaguer Autonell, Joan; Vives Pi, Marta (Frontiers Media, 2020-05-13)
      Type 1 diabetes is an autoimmune disease caused by the destruction of the insulin-producing β-cells. An ideal immunotherapy should combine the blockade of the autoimmune response with the recovery of functional target cell ...
    • Resistant/Refractory Hypertension and Sleep Apnoea: Current Knowledge and Future Challenges 

      Oscullo, Grace; Torres, Gerard; Campos-Rodríguez, Francisco; Posadas, Tomás; Reina-González, Angela; Sapiña Beltrán, Esther; Barbé Illa, Ferran; Martínez-García, Miguel Angel (MDPI, 2019)
      Hypertension is one of the most frequent cardiovascular risk factors. The population of hypertensive patients includes some phenotypes whose blood pressure levels are particularly difficult to control, thus putting them ...
    • Reversible glutathionylation of Sir2 by monothiol glutaredoxins Grx3/4 regulates stress resistance 

      Vall-llaura Espinosa, Núria; Reverter Branchat, Gemma; Vived Maza, Celia; Weertman, Naomi; Rodríguez Colman, Maria José; Cabiscol Català, Elisa (Elsevier, 2016)
      The regulatory mechanisms of yeast Sir2, the founding member of the sirtuin family involved in oxidative stress and aging, are unknown. Redox signaling controls many cellular functions, especially under stress situations, ...
    • Risk factors are different for deep and lobar remote hemorrhages after intravenous thrombolysis 

      Prats Sánchez, Luis; Martínez Domeño, Alejandro; Camps Renom, Pol; Delgado Mederos, Raquel; Guisado Alonso, Daniel; Marín, Rebeca; Dorado, Laura; Rudilosso, Salvatore; Gómez González, Alejandra; Purroy Garcia, Francisco; Gómez Choco, Manuel; Cánovas, David; Cocho, Dolores; Garces, Moises; Abilleira i Castells, Sònia; Martí Fàbregas, Joan (Public Library so Science, 2017)
      Remote parenchymal haemorrhage (rPH) after intravenous thrombolysis is defined as hem- orrhages that appear in brain regions without visible ischemic damage, remote from the area of ischemia causing the initial stroke ...
    • Risk of exacerbation in chronic obstructive pulmonary disease: a primary care retrospective cohort study 

      Montserrat i Capdevila, Josep; Godoy i García, Pere; Marsal Mora, Josep Ramon; Barbé Illa, Ferran; Galván, Leonardo (BioMed Central, 2015)
      Background: The risk of exacerbation in chronic obstructive pulmonary disease (COPD) depends on the severity of disease and other less well known factors. Predictive models of exacerbation are more accurate than the forced ...
    • Role of Epidermal Growth Factor Receptor (EGFR) and Its Ligands in Kidney Inflammation and Damage 

      Rayego Mateos, Sandra; Rodrigues-Diez, Raul; Morgado-Pascual, José L.; Valentijn, Floris; Valdivielso Revilla, José Manuel; Goldschmeding, Roel; Ruiz-Ortega, Marta (Hindawi Publishing Corporation, 2018)
      Chronickidneydisease (CKD)ischaracterized bypersistent inflammationandprogressive fibrosis,ultimatelyleadingto end-stage renal disease. Although many studies have investigated the factors involved in the progressive deterioration ...