Now showing items 715-734 of 1089

    • Non-invasive imaging techniques and assessment of carotid vasa vasorum neovascularization: promises and pitfalls 

      Pereira, Tania; Betriu i Bars, M. Àngels; Alves, Rui (Elsevier, 2018)
      Carotid adventitia vasa vasorum neovascularization (VVn) is associated with the initial stages of arteriosclerosis and with the formation of unstable plaque. However, techniques to accurately quantify that neovascularization ...
    • Non-linear association between diabetes mellitus and pulmonary function: a population-based study 

      Zhang, Rui‑Heng; Zhou, Jian‑Bo; Cai, Yao‑Hua; Shu, Lin‑Ping; Simó, Rafael; Lecube Torelló, Albert (BMC, 2020)
      Background: There is increasing evidence that the lung is a target organ of diabetes. This study aimed to examine in detail the association between diabetes mellitus and pulmonary function using a national cohort. We also ...
    • Non-occupational protein contact dermatitis induced by mango fruit 

      Pesqué, David; Canal Garcia, Elena; Rozas-Muñoz, Eduardo; Pujol Vallverdú, Ramon M.; Giménez Arnau, Ana M. (John Wiley & Sons Ltd, 2021-06)
      Immediate contact skin reactions are considered a subset of the contact urticaria syndrome, which includes contact urticaria and protein contact dermatitis (PCD). These entities clinically manifest as development of wheals, ...
    • Nonalcoholic Fatty Liver Disease and the Gut-Liver Axis: Exploring an Undernutrition Perspective 

      Bauer, Kylynda C.; Littlejohn, Paula T.; Ayala Jové, Ma. Victoria (Maria Victoria); Creus Cuadros, Anna; Finlay, Barton Brett (AGA Institute; Elsevier, 2022)
      Nonalcoholic fatty liver disease (NAFLD) is a chronic con dition affecting one quarter of the global population. Although primarily linked to obesity and metabolic syn drome, undernutrition and the altered (dysbiotic) gut ...
    • Non‑linear association of anthropometric measurements and pulmonary function 

      Zhang, Rui‑Heng; Zhou, Jian‑Bo; Cai, Yao‑Hua; Shu, Lin‑Ping; Yang, Jinkui; Wei, Wenbin; Lecube Torelló, Albert (Nature Research, 2021)
      This study examined the association of anthropometric measurements [body mass index (BMI), waist circumference (WC), percentage body fat (PBF), body roundness index (BRI) and A Body Shape Index (ABSI)] with pulmonary ...
    • Notch signaling pathway is activated in motoneurons of spinal muscular atrophy 

      Cardona-Rossinyol, Andrea; Garcera, Ana; Torres-Benito, Laura; Soler i Tatché, Rosa Ma.; Tabares, Lucía; Lladó, Jerònia; Olmos, Gabriel; Caraballo-Miralles, Víctor (MDPI, 2013)
      Spinal muscular atrophy (SMA) is a neurodegenerative disease produced by low levels of Survival Motor Neuron (SMN) protein that affects alpha motoneurons in the spinal cord. Notch signaling is a cell-cell communication ...
    • Novel DNMT3A Germline Variant in a Patient with Multiple Paragangliomas and Papillary Thyroid Carcinoma 

      Mellid, Sara; Coloma, Javier; Calsina, Bruna; Monteagudo, María; Roldán Romero, Juan M.; Santos, María; Leandro García, Luis J.; Lanillos, Javier; Martínez Montes, Ángel M.; Rodríguez-Antona, Cristina; Montero Conde, Cristina; Martínez López, Joaquín; Ayala, Rosa; Matias-Guiu, Xavier; Robledo, Mercedes; Cascón, Alberto (MDPI, 2020)
      Over the past few years, next generation technologies have been applied to unravel the genetics of rare inherited diseases, facilitating the discovery of new susceptibility genes. We recently found germline DNMT3A ...
    • NRN1 Gene as a Potential Marker of Early-Onset Schizophrenia: Evidence from Genetic and Neuroimaging Approaches 

      Almodóvar Payá, Carmen; Guardiola Ripoll, Maria; Giralt López, Maria; Gallego, Carme; Salgado Pineda, Pilar; Miret, Salvador; Salvador, Raymond; Muñoz, María J.; Lázaro, Luisa; Guerrero Pedraza, Amalia; Parellada, Mara; Carrión, María I.; Cuesta, Manuel J.; Maristany, Teresa; Sarró, Salvador; Fañanás Saura, Lourdes; Callado, Luis F.; Arias, Bárbara; Pomarol-Clotet, Edith; Fatjó-Vilas, Mar (MDPI, 2022)
      Included in the neurotrophins family, the Neuritin 1 gene (NRN1) has emerged as an attractive candidate gene for schizophrenia (SZ) since it has been associated with the risk for the disorder and general cognitive performance. ...
    • Nuclear monothiol glutaredoxins of Saccharomyces cerevisiae can function as mitochondrial glutaredoxins 

      Molina Navarro, Maria Micaela; Bellí i Martínez, Gemma; Torre Ruiz, M. A. de la; Rodríguez Manzanaque, Maria Teresa; Herrero Perpiñán, Enrique (The American Society for Biochemistry and Molecular Biology, 2004)
      Glutaredoxins are thiol oxidoreductases that regulate protein redox state. In Saccharomyces cerevisiae, Grx1 and Grx2 are cytosolic dithiol glutaredoxins, whereas Grx3, Grx4, and Grx5 are monothiol glutaredoxins. ...
    • Nursing knowledge of and attitude in cardiopulmonary arrest: cross-sectional survey analysis 

      Tíscar González, Verónica; Blanco Blanco, Joan; Gea Sánchez, Montserrat; Rodriguez-Molinuevo, Ascensión; Moreno-Casbas, Maria Teresa (PeerJ, 2019)
      Background Nurses are often the first to activate the chain of survival when a cardiorespiratory arrest happens. That is why it is crucial that they keep their knowledge and skills up-to-date and their attitudes to ...
    • Nusinersen ameliorates motor function and prevents motoneuron Cajal body disassembly and abnormal poly(A) RNA distribution in a SMA mouse model 

      Berciano, Maria T.; Puente-Bedia, Alba; Medina‑Samamé, Almundena; Rodriguez-Rey, José C.; Calderó i Pardo, Jordi; Lafarga, Miguel; Tapia, Olga (Nature Publishing Group, 2020)
      Spinal muscular atrophy (SMA) is a devastating autosomal recessive neuromuscular disease characterized by degeneration of spinal cord alpha motor neurons (αMNs). SMA is caused by the homozygous deletion or mutation of the ...
    • Obesity attenuates the effect of sleep apnea on active TGF-ß1 levels and tumor aggressiveness in patients with melanoma 

      Cubillos‑Zapata, Carolina; Martínez‑García, Miguel Ángel; Díaz‑García, Elena; Jaureguizar, Ana; Campos‑Rodríguez, Francisco; Sánchez de la Torre, Manuel; Nagore, Eduardo; Martorell‑Calatayud, Antonio; Hernández Blasco, Luis; Pastor, Esther; Abad, Jorge; Montserrat, Josep Maria; Cabriada‑Nuño, Valentín; Cano‑Pumarega, Irene; Corral-Peñafiel, Jaime; Arias, Eva; Mediano, Olga; Somoza, María; Dalmau-Arias, Joan; Almendros, Isaac; Farré, Ramon; López‑Collazo, Eduardo; Gozal, David; García Río, Francisco (Nature Research, 2020)
      Active transforming growth factor-β1 (TGF-β1), a cytokine partially regulated by hypoxia and obesity, has been related with poor prognosis in several tumors. We determine whether obstructive sleep apnea (OSA) increases ...
    • Obesity changes the human gut mycobiome 

      Portero Otín, Manuel; Pamplona Gras, Reinald; Jové Font, Mariona; Rodríguez, M. Mar; Pérez, Daniel; Chaves, Felipe Javier; Esteve, Eduardo; Marin-Garcia, Pablo; Xifra, Gemma; Vendrell, Joan; Ricart, Wifredo; Chacón, Matilde R.; Fernández Real, José Manuel (Nature Publishing Group, 2015)
      The human intestine is home to a diverse range of bacterial and fungal species, forming an ecological community that contributes to normal physiology and disease susceptibility. Here, the fungal microbiota (mycobiome) in ...
    • Obesity in Patients with Type 1 Diabetes: Links, Risks and Management Challenges 

      Vilarrasa, Núria; San Jose, Patricia; Rubio, Miguel Ángel; Lecube Torelló, Albert (Dove Medical Press, 2021)
      Obesity affects large numbers of patients with type 1 diabetes (T1D) across their lifetime, with rates ranging between 2.8% and 37.1%. Patients with T1D and obesity are characterized by the presence of insulin resistance, ...
    • Obesity, a Diet-Induced Inflammatory Disease 

      Lecube Torelló, Albert; López Cano, Carolina (MDPI, 2019)
    • Obesity-associated deficits in inhibitory control are phenocopied to mice through gut microbiota changes in one-carbon and aromatic amino acids metabolic pathways 

      Arnoriaga Rodríguez, María; Mayneris Perxachs, Jordi; Contreras-Rodríguez, Oren; Burokas, Aurelijus; Ortega Sánchez, Juan Antonio; Blasco Solà, Gerard; Coll, Claudia; Biarnés, Carles; Castells Nobau, Anna; Puig, Josep; Garre Olmo, Josep; Ramos, Rafel; Pedraza, Salvador; Brugada, Ramon; Vilanova, Joan Carles; Serena, Joaquín; Barretina Ginesta, Jordi; Gich Fullà, Jordi; Pérez Brocal, Vicente; Moya, Andrés; Fernández Real, Xavier; Ramió Torrentà, Lluís; Pamplona Gras, Reinald; Sol, Joaquim; Jové Font, Mariona; Ricart, Wifredo; Portero Otín, Manuel; Maldonado, Rafael; Fernández Real, José Manuel (BMJ Publishing Group; British Society of Gastroenterology, 2021-01)
      Background Inhibitory control (IC) is critical to keep long-term goals in everyday life. Bidirectional relationships between IC deficits and obesity are behind unhealthy eating and physical exercise habits. Methods We ...
    • Observational multicenter study to evaluate the prevalence and prognosis of subclinical atheromatosis in a Spanish chronic kidney disease cohort: baseline data from the NEFRONA study 

      Arroyo, David; Betriu i Bars, M. Àngels; Martínez Alonso, Montserrat; Vidal Amat, Teresa; Valdivielso Revilla, José Manuel; Fernández i Giráldez, Elvira (BioMed Central, 2014)
      Background: Cardiovascular events (CVE) are more prevalent in chronic kidney disease (CKD) than in general population, being the main cause of morbimortality. Specific risk factors related to CKD have been suggested, because ...
    • Obstructive sleep apnea and its malajemente in patients with atrial fibrillation: An International Collaboration of Sleep Apnea Cardiovascular Trialists (INCOSACT) global survey of practicing cardiologists 

      Faulx, Michael D.; Mehra, Reena; Geovanini, Glaucylara Reis; Ando, Shin-Ichi; Arzt, Michael; Drager, Luciano; Fu, Michael; Hoyos, Camilla; Hai, Jo; Hwang, Juey-Jen; Karaoguz, Remzi; Kimoff, John; Lee, Pei-Lin; Mediano, Olga; Patel, Sanjay R.; Peker, Yüksel; Pepin, Jean Louis; Sánchez de la Torre, Manuel; Sériès, Frédéric; Stadler, Stefan; Strollo, Patrick; Tahrani, A. A.; Thunström, Erik; Yamauchi, Motoo; Redline, Susan; Phillips, Craig L. (Elsevier, 2022)
      Background: Among international cardiologists it is unclear whether equipoise exists regarding the benefit of diagnosing and managing obstructive sleep apnea (OSA) to improve atrial fibrillation (AF) outcomes and whether ...
    • Obstructive Sleep Apnea: Emerging Treatments Targeting the Genioglossus Muscle 

      Mediano, Olga; Romero-Peralta, Sofia; Resano, Pilar; Cano-Pumarega, Irene; Sánchez de la Torre, Manuel; Castillo-García, María; Martínez-Sánchez, Ana Belén; Ortigado, Ana; García-Río, Francisco (MDPI, 2019)
      Obstructive sleep apnea (OSA) is characterized by repetitive episodes of upper airway obstruction caused by a loss of upper airway dilator muscle tone during sleep and an inadequate compensatory response by these muscles ...
    • Obstructive sleep apnea: in search of precision 

      Sánchez de la Torre, Manuel; Gozal, David (Taylor & Francis, 2017)
      Introduction: Obstructive sleep apnea (OSA) is a highly prevalent condition that is viewed as a major global health concern, while affecting approximately 10% of the middle-aged population. OSA is a chronic disease that ...