Now showing items 71-90 of 935

    • L'aplicació d'anticossos monoclonals en terapèutica humana: Farmacologia general i indicacions concretes 

      Boix Torras, Jacint; Cirera i Torres, Judit (Col·legi Oficial de Metges de Lleida, 2009)
    • Apoptotic cell death and altered calcium homeostasis caused by frataxin depletion in dorsal root ganglia neurons can be prevented by BH4 domain of Bcl-xL protein 

      Tasheva, Stefka Mincheva; Obis Monné, Èlia; Tamarit Sumalla, Jordi; Ros Salvador, Joaquim (Oxford University Press, 2014)
      Friedreich ataxia (FRDA) is a neurodegenerative disease characterized by a decreased expression of the mitochondrial protein frataxin. Major neurological symptoms of the disease are due to degeneration of dorsal root ganglion ...
    • Are Obesity Indices Useful for Detecting Subclinical Atheromatosis in a Middle-Aged Population? 

      Sánchez Peña, Enric; Sánchez, Marta; Betriu i Bars, M. Àngels; Rius, Ferran; Torres, Gerard; Purroy Garcia, Francisco; Pamplona Gras, Reinald; Ortega, Marta; López Cano, Carolina; Hernández García, Marta; Bueno Díez, Marta; Fernández i Giráldez, Elvira; Salvador, Javier; Lecube Torelló, Albert; ILERVAS project collaborators (Karger Publishers, 2020)
      Objective: There is a close relationship between excess adiposity and cardiovascular disease. Although body mass index (BMI) is the most used approach to estimate excess weight, other anthropometric indices have been ...
    • Assessing sleep health in a European population: results of the catalan health survey 2015 

      Dalmases, Mireia; Benítez, Iván; Mas, Anna; Garcia-Codina, Oriol; Medina-Bustos, Antonia; Escarrabill, Joan; Saltó, Esteve; Buysse, Daniel J.; Roure, Núria; Sánchez de la Torre, Manuel; Rué i Monné, Montserrat; Barbé Illa, Ferran; Batlle Garcia, Jordi de (Public Library of Science, 2018)
      Objective To describe the overall sleep health of the Catalan population using data from the 2015 Catalan Health Survey and to compare the performance of two sleep health indicators: sleep duration and a 5-dimension sleep ...
    • Assessing the impact of early detection biases on breast cancer survival of Catalan women 

      Roso-Llorach, Albert; Forné Izquierdo, Carles; Macià, Francesc; Galcerán, Jaume; Marcos-Gragera, Rafael; Rué i Monné, Montserrat (Institut d'Estadística de Catalunya, 2014)
      Survival estimates for women with screen-detected breast cancer are affected by biases specific to early detection. Lead-time bias occurs due to the advance of diagnosis, and length-sampling bias because tumors detected ...
    • Assessment of corneal biomechanical properties and intraocular pressure in myopic spanish healthy population 

      Buey, María A. del; Lavilla, Laura; Ascaso, Francisco J.; Lanchares, Elena; Huerva, Valentín; Cristóbal, José A. (Hindawi Publishing Corporation, 2014)
      Purpose. To examine biomechanical parameters of the cornea in myopic eyes and their relationship with the degree of myopia in a western healthy population. Methods. Corneal hysteresis (CH), corneal resistance factor (CRF), ...
    • Assessment of Inner Retinal Layers and Choroidal Thickness in Type 1 Diabetes Mellitus: A Cross-Sectional Study 

      Carbonell, Marc; Alonso, Núria; Castelblanco Echavarría, Esmeralda; Real, Jordi; Ramírez-Morros, Anna; Simó, Rafael; Hernández, Cristina; Jurjo Campo, Carmen; Traveset Maeso, Alicia; Valldeperas, Xavier; Mauricio Puente, Dídac (MDPI, 2019)
      Recent studies have shown that retinal neurodegeneration may precede visible vascular changes in diabetic retinopathy (DR). In addition, the relationship of choroidal thickness (CT) with DR stage is not well defined. To ...
    • Assessment of the effects of decision aids about breast cancer screening: a systematic review and meta-analysis 

      Martínez Alonso, Montserrat; Carles Lavila, Misericordia; Pérez Lacasta, María José; Pons Rodríguez, Anna; Garcia, Montse; Rué i Monné, Montserrat (BMJ Publishing Group, 2017)
      The aim of this systematic review and meta-analysis of randomised controlled trials (RCTs) and observational studies is to assess the effect of decision aids (DAs) in women aged 50 and below facing the decision to be ...
    • Assessment of the influence of direct tobacco smoke on infection and active TB management 

      Altet, Neus; Latorre, Irene; Jiménez-Fuentes, María Ángeles; Maldonado, José; Molina, Israel; Milà, Celia; García-García, Esther; Villar-Hernández, Raquel; Laabei, Maisem; Gómez, Andromeda-Celeste; Godoy i García, Pere; de Souza-Galvão, Maria Luiza; Solano, Segismundo; Jiménez-Ruiz, Carlos A.; Domínguez, Jose (Public Library of Science, 2017)
      Smoking is a risk factor for tuberculosis (TB) infection and disease progression. Tobacco smoking increases susceptibility to TB in a variety of ways, one of which is due to a reduction of the IFN-γ response. Consequently, ...
    • Association between Obstructive Sleep Apnea and Community-Acquired Pneumonia 

      Chiner, Eusebi; Llombart, Mónica; Valls Marsal, Joan; Pastor, Esther; Sancho-Chust, José; Luz Andreu, Ada; Sánchez de la Torre, Manuel; Barbé Illa, Ferran (Public Library of Science, 2016)
      Background: We hypothesized that obstructive sleep apnea (OSA) can predispose individuals to lower airway infections and community-acquired pneumonia (CAP) due to upper airway microaspiration. This study evaluated the ...
    • Association between Sick Leave Prescribing Practices and Physician Burnout and Empathy 

      Yuguero Torres, Oriol; Esquerda i Aresté, Montse; Marsal Mora, Josep Ramon; Soler González, Jorge (Public Library of Science, 2015-07-21)
      Objectives: To investigate the association between sick leave prescription and physician burnout and empathy in a primary care health district in Lleida, Spain. Methods: This descriptive study included 108 primary care ...
    • Association of BST-2 Gene Variants With HIV Disease Progression Underscores the Role of BST-2 in HIV Type 1 Infection 

      Laplana Lafaja, Marina; Caruz, Antonio; Pineda, Juan Antonio; Puig, Teresa; Fibla Palazón, Joan (Oxford University Press, 2013-02-01)
      We tested bone marrow stromal cell antigen 2 (BST-2) gene variants rs3217318, a 19-base-pair insertion/deletion polymorphism in the promoter region, and rs10415893, a tag single-nucleotide polymorphism in the 3′ untranslated ...
    • Association of Candidate Gene Polymorphisms With Chronic Kidney Disease: Results of a Case-Control Analysis in the Nefrona Cohort 

      Valls, Joan; Cambray Carner, Serafí; Pérez-Guallar, Carles; Bozić Stanojević, Milica; Bermúdez López, Marcelino; Fernández i Giráldez, Elvira; Betriu i Bars, M. Àngels; Rodríguez, Isabel; Valdivielso Revilla, José Manuel (Frontiers Media, 2019)
      Chronic kidney disease (CKD) is a major risk factor for end-stage renal disease, cardiovascular disease and premature death. Despite classical clinical risk factors for CKD and some genetic risk factors have been identified, ...
    • Association of complement receptor 2 polymorphisms withinnate resistance to HIV-1 infection 

      Herrero, Rocío; Real, Luis M.; Rivero-Juárez, Antonio; Pineda, Juan Antonio; Camacho, Ángela; Macías, Juan; Laplana Lafaja, Marina; Konieczny, Piotr; Márquez, Francisco J.; Souto, Juan Carlos; Soria, José Manuel; Saulle, Irma; Lo Caputo, Sergio; Biasin, Mara; Rivero, Antonio; Fibla Palazón, Joan; Caruz, Antonio (Springer Nature, 2015-03)
      HIV-1 induces activation of complement through the classical and lectin pathways. However, the virus incorporates several membrane-bound or soluble regulators of complement activation (RCA) that inactivate complement. HIV-1 ...
    • Association of FGF-2 Concentrations with Atheroma Progression in Chronic Kidney Disease Patients 

      Bozić Stanojević, Milica; Betriu i Bars, M. Àngels; Bermúdez López, Marcelino; Ortiz, Alberto; Fernández i Giráldez, Elvira; Valdivielso Revilla, José Manuel (American Society of Nephrology, 2018)
      Background and objectives: Atherosclerosis is highly prevalent in CKD. The rate of progression of atherosclerosis is associated with cardiovascular events. Fibroblast growth factor 2 (FGF-2) is a member of the FGF family ...
    • Association of low oleic acid intake with diabetic retinopathy in type 2 diabetic patients: a case–control study 

      Alcubierre Calvo, Núria; Navarrete Muñoz, Eva María; Rubinat, Esther; Falguera, Mireia; Valls Marsal, Joan; Traveset Maeso, Alicia; Vilanova, María-Belén; Marsal Mora, Josep Ramon; Hernández, Marta; Granado Casas, Minerva; Martínez González, María Dolores; Jurjo Campo, Carmen; Franch-Nadal, Josep; Vioque, Jesus; Mauricio Puente, Dídac (BioMed Central, 2016)
      Background: The objective of this study was to describe the intake of macronutrient, especially fatty acids, and explore their possible effect on diabetic retinopathy (DR) in patients with type 2 diabetes mellitus. Methods: ...
    • Association of serum phosphorus with subclinical atherosclerosis in chronic kidney disease. Sex makes a difference 

      Martín, Marisa; Valls Marsal, Joan; Betriu i Bars, M. Àngels; Fernández i Giráldez, Elvira; Valdivielso Revilla, José Manuel (Elsevier, 2015-02-28)
      Abstract BACKGROUND: Cardiovascular disease is the leading cause of mortality in chronic kidney disease (CKD). Serum phosphate has been associated to cardiovascular disease in the general population and this effect seems ...
    • ATPase-dependent control of the Mms21 SUMO ligase during DNA repair 

      Bermúdez López, Marcelino; Pociño Merino, Irene; Sánchez, Humberto; Bueno, Andrés; Guasch, Clàudia; Almedawar, Seba; Brú i Virgili, Sergi; Garí Marsol, Eloi; Wyman, Claire; Reverter Cendrós, David; Colomina i Gabarrella, Neus; Torres Rosell, Jordi (Plos Biology, 2015-03-12)
      Modification of proteins by SUMO is essential for the maintenance of genome integrity. During DNA replication, the Mms21-branch of the SUMO pathway counteracts recombination intermediates at damaged replication forks, thus ...
    • Auditing the management of vaccine-preventable disease outbreaks: the need for a tool 

      Torner Gràcia, Núria; Carnicer-Pont, Dolors; Castilla, Jesús; Cayla, Joan; Godoy i García, Pere; Domínguez García, Àngela; Epidemiological Surveillance Working Group of Catalonia and Navarre (Public Library of Science, 2011)
      Public health activities, especially infectious disease control, depend on effective teamwork. We present the results of a pilot audit questionnaire aimed at assessing the quality of public health services in the management ...
    • Autophagy exacerbates caspase-dependent apoptotic cell death after short times of starvation 

      Mattiolo, Paolo; Yuste Mateos, Víctor J. (Víctor José); Boix Torras, Jacint; Ribas i Fortuny, Judit (Elsevier, 2015-12)
      Autophagy is generally regarded as a mechanism to promote cell survival. However, autophagy can occasionally be the mechanism responsible of cell demise. We have found that a concomitant depletion of glucose, nutrients and ...