Now showing items 684-703 of 935

    • Prevalence of pre-diabetes and undiagnosed diabetes in the Mollerussa prospective observational cohort study in a semi-rural area of Catalonia 

      Falguera, Mireia; Vilanova, María-Belén; Alcubierre Calvo, Núria; Granado Casas, Minerva; Marsal Mora, Josep Ramon; Miró, Neus; Cebrian, Cristina; Molló Inesta, Àngels; Franch-Nadal, Josep; Mata Cases, Manel; Castelblanco Echavarría, Esmeralda; Mauricio Puente, Dídac (BMJ, 2020-01-07)
      Objectives: To assess the prevalence of undiagnosed diabetes and pre-diabetes in the healthy population in the Mollerussa cohort. As a secondary objective, to identify the variables associated with these conditions and to ...
    • Prevalencia y características de la enfermedad pulmonar obstructiva crónica en no fumadores 

      Montserrat i Capdevila, Josep; Godoy i García, Pere; Marsal Mora, Josep Ramon; Ortega Bravo, Marta; Barbé Illa, Ferran; Castañ, Maria Teresa; Seminario, Asunción; Pujol Salud, Jesús; Alsedà Graells, Miquel (Elsevier, 2018)
      Objetivo Conocer el perfil y las características de los enfermos diagnosticados de enfermedad pulmonar obstructiva crónica (EPOC) y que nunca han sido fumadores. Diseño Estudio descriptivo transversal. Emplazamiento Área ...
    • proBDNF is modified by advanced glycation end products in Alzheimer’s disease and causes neuronal apoptosis by inducing p75 neurotrophin receptor processing 

      Fleitas Pérez, Catherine; Piñol Ripoll, Gerard; Marfull Oromí, Pau; Rocandio, Daniel; Ferrer, Isidre; Rampon, Claire; Egea Navarro, Joaquim; Espinet Mestre, Carme (BMC, 2018)
      Alzheimer disease (AD) is a complex pathology related to multiple causes including oxidative stress. Brain-derived neurotrophic factor (BDNF) is a neutrotrophic factor essential for the survival and differentiation of ...
    • Productos finales de glicación avanzada en la obesidad mórbida y tras la cirugía bariátrica: cuando la memoria glucémica empieza a fallar 

      Sánchez Peña, Enric; Baena-Fustegueras, Juan A; Fuente Juárez, Mari Cruz de la; Gutiérrez Carrasquilla, Liliana; Bueno Díez, Marta; Ros López, Susana; Lecube Torelló, Albert (Elsevier España, 2017-01-18)
      Antecedentes y objetivo: Los productos finales de glicación avanzada (AGE) son un indicador de memoria metabólica. Su concentración se incrementa cuando existe estrés oxidativo, inflamación o hiperglucemia crónica. Se ...
    • Profiles of Motor Laterality in Young Athletes' Performance of Complex Movements: Merging the MOTORLAT and PATHoops Tools 

      Castañer Balcells, Marta; Andueza Azcona, Juan A.; Hileno González, Raúl; Puigarnau Coma, Sílvia; Prat Ambrós, Queralt; Camerino Foguet, Oleguer (Frontiers Media, 2018)
      Laterality is a key aspect of the analysis of basic and specific motor skills. It is relevant to sports because it involves motor laterality profiles beyond left-right preference and spatial orientation of the body. The ...
    • Prognostic value of symptoms at lung cancer diagnosis: a three-year observational study 

      Polanco, Dinora; Pinilla, Lucía; Gracia-Lavedan, Esther; Mas, Anna; Bertran, Sandra; Fierro, Gemma; Seminario, Asunción; Gómez Falguera, Silvia; Barbé Illa, Ferran (AME Publishing, 2021-03)
      Background: Lung cancer is mainly diagnosed at advanced or locally advanced stages, usually when symptoms become evident. However, sometimes it may be diagnosed incidentally during routine care, while patients are still ...
    • Prokaryotic and eukaryotic monothiol glutaredoxins are able to perform the functions of Grx5 in the biogenesis of Fe/S clusters in yeast mitochondria 

      Molina Navarro, Maria Micaela; Casas Herranz, Celia; Piedrafita Llorens, Lídia; Bellí i Martínez, Gemma; Herrero Perpiñán, Enrique (Elsevier, 2003)
      The Saccharomyces cerevisiae monothiol glutare- doxin Grx5 participates in the mitochondrial biogenesis of iron–sulfur clusters. Grx5 homologues exist in organisms from bacteria to humans. Chicken (cGRX5) and human ...
    • Proposal for the creation of a national strategy for precision medicine in cancer: a position statement of SEOM, SEAP and SEFH 

      Garrido, Pilar; Aldaz, Azucena; Calleja, Miguel Ángel; Álava, Enrique de; Lamas, María Jesús; Martín, Miguel; Matias-Guiu, Xavier; Palacios, José; Vera, Ruth (Aula Médica Ediciones, 2017)
      Precision medicine is an emerging approach for disease treatment and prevention that takes into account individual variability in genes, environment, and lifestyle for each person. Precision medicine is transforming ...
    • Proposal for the creation of a national strategy for precision medicine in cancer: a position statement of SEOM, SEAP,and SEFH 

      Garrido, Pilar; Aldaz, Azucena; Vera, Ruth; Calleja, Miguel Ángel; Álava, Enrique de; Martín, Miguel; Matias-Guiu, Xavier; Palacios, José (Springer, 2018)
      Precision medicine is an emerging approach for disease treatment and prevention that takes into account individual variability in genes, environment, and lifestyle for each person. Precision medicine is transforming ...
    • Prostate-targeted radiosensitization via aptamer-shRNA chimeras in human tumor xenografts 

      Ni, Xiaohua; Zhang, Yonggang; Ribas i Fortuny, Judit; Chowdhury, Wasim H.; Castanares, Mark; Zhang, Zhewei; Laiho, Marikki; DeWeese, Theodore L.; Lupold, Shawn E. (American Society for Clinical Investigation, 2011)
      Dose-escalated radiation therapy for localized prostate cancer (PCa) has a clear therapeutic benefit; however, escalated doses may also increase injury to noncancerous tissues. Radiosensitizing agents can improve ...
    • Protective role of renal proximal tubular alpha-synuclein in the pathogenesis of kidney fibrosis 

      Bozić Stanojević, Milica; Caus Enríquez, Maite; Rodrigues-Diez, Raul; Pedraza González, Neus; Ruiz-Ortega, Marta; Garí Marsol, Eloi; Gallel Vicente, María del Pilar; Panadés, Maria José; Martinez, Ana; Fernández i Giráldez, Elvira; Valdivielso Revilla, José Manuel (Nature Publishing Group, 2020)
      Kidney fibrosis is a highly deleterious process and a final manifestation of chronic kidney disease. Alpha-(α)-synuclein (SNCA) is an actin-binding neuronal protein with various functions within the brain; however, its ...
    • Protein carbonylation: proteomics, specificity and relevance to aging 

      Cabiscol Català, Elisa; Tamarit Sumalla, Jordi; Ros Salvador, Joaquim (Wiley, 2013)
      Detection and quantification of protein carbonyls present in biological samples has become a popular, albeit indirect, method to determine the existence of oxidative stress. Moreover, the rise of proteomics has allowed ...
    • Protein Kinase KIS Localizes to RNA Granules and Enhances Local Translation 

      Cambray Carner, Serafí; Pedraza González, Neus; Rafel i Borrell, Marta; Garí Marsol, Eloi; Aldea, Martí; Gallego, Carme (American Society for Microbiology, 2009)
      The regulation of mRNA transport is a fundamental process for cytoplasmic sorting of transcripts and spatially controlled translational derepression once properly localized. There is growing evidence that translation is ...
    • Protein oxidation in Huntington disease 

      Sorolla Bardají, Maria Alba; Rodríguez Colman, Maria José; Vall-llaura Espinosa, Núria; Tamarit Sumalla, Jordi; Ros Salvador, Joaquim; Cabiscol Català, Elisa (Wiley, 2012-05)
      Huntington disease (HD) is an inherited neurodegenerative disorder caused by expansion of CAG repeats in the huntingtin gene, affecting initially the striatum and progressively the cortex. Oxidative stress, and consequent ...
    • Protein oxidation in Huntington disease affects energy production and vitamin B6 metabolism 

      Sorolla Bardají, Maria Alba; Rodríguez Colman, Maria José; Tamarit Sumalla, Jordi; Ortega, Zaira; Lucas, José J.; Ferrer, Isidre; Ros Salvador, Joaquim; Cabiscol Català, Elisa (Elsevier, 2010)
      Huntington disease (HD) is an inherited neurodegenerative disorder that initially affects the striatum and progressively the cortex. Oxidative stress in HD has been described as important to disease progression. In ...
    • Protein targets of oxidative damage in human neurodegenerative diseases with abnormal protein aggregates 

      Martínez, Anna; Portero Otín, Manuel; Pamplona Gras, Reinald; Ferrer, Isidre (Wiley, 2010)
      Human neurodegenerative diseases with abnormal protein aggregates are associated with aberrant post-translational modifications, solubility, aggregation and fibril formation of selected proteins which cannot be degraded ...
    • Proteomic and oxidative stress analysis in human brain samples of Huntington disease 

      Sorolla Bardají, Maria Alba; Reverter Branchat, Gemma; Tamarit Sumalla, Jordi; Ferrer, Isidre; Ros Salvador, Joaquim; Cabiscol Català, Elisa (Elsevier, 2008)
      Huntington disease (HD) is a neurodegenerative disorder caused by expansion of CAG repeats in exon 1 of the huntingtin gene, affecting initially the striatum and progressively the cortex. This work reports a proteomic analysis ...
    • Pseudophakic cystoid macular edema: update 2016 

      Grzybowski, Andrzej; Sikorski, Bartosz L; Ascaso, Francisco J.; Huerva, Valentín (Dovepress, 2016)
      Pseudophakic cystoid macular edema (PCME) is the most common complication of cataract surgery, leading in some cases to a decrease in vision. Although the pathogenesis of PCME is not completely understood, the contribution ...
    • Psoriasis, metabolic syndrome and cardiovascular risk factors. A population-based study. 

      Fernández Armenteros, José Manuel; Gómez Arbonés, Javier; Buti, Miquel; Betriu i Bars, M. Àngels; Sanmartín Novell, Verònica; Ortega Bravo, Marta; Martínez Alonso, Montserrat; Garí Marsol, Eloi; Portero Otín, Manuel; Santamaria-Babi, L.; Casanova i Seuma, Josep M. (Josep Manel) (Wiley, 2019)
      Abstract Background: Psoriasis is a very prevalent systemic chronic inflammatory disease. Major cardiovascular events are the main cause of mortality in these patients which suggests an association between psoriasis and ...
    • Psychological Well-Being in Nursing Students: A Multicentric, Cross-Sectional Study 

      Reverté-Villarroya, Sílvia; Ortega, Laura; Raigal Aran, Laia; Sauras Colón, Esther; Ricomà Muntané, Roser; Ballester-Ferrando, D.; Rascón Hernán, C.; Botigué, Teresa; Lavedán, Ana; González Osorio, L.; Osorio Spuler, X.; Burjalés, D. (MDPI, 2021-03-15)
      In addition to complying with strict academic standards, nursing students must acquire relevant knowledge and skills, and learn how to carry themselves in different and often stressful professional settings. These obligations ...