Browsing Articles publicats (IRBLleida) by Title
Now showing items 893-903 of 903
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When cholesterol is not cholesterol: a note on the enzymatic determination of its concentration in model systems containing vegetable extracts
(BioMed Central, 2010)Background: Experimental evidences demonstrate that vegetable derived extracts inhibit cholesterol absorption in the gastrointestinal tract. To further explore the mechanisms behind, we modeled duodenal contents with several ... -
Whi3 regulates morphogenesis in budding yeast by enhancing Cdk functions in apical growth
(Landes Bioscience, 2009)The Whi3 protein is associated with the endoplasmic reticulum, interacts with Cdc28, the budding-yeast Cdk, binds the mRNA of cyclin CLN3 and prevents accumulation of the Cdc28-Cln3 in the nucleus until late G1. Besides ... -
Whi3, a developmental regulator of budding yeast, binds a large set of mRNAs functionally related to the endoplasmic reticulum
(American Society for Biochemistry and Molecular Biology, 2008)Whi3 is an RNA-binding protein associated with the endoplasmic reticulum (ER) that binds the CLN3 mRNA and plays a key role in the efficient retention of cyclin Cln3 at the ER. In the present work, we have identified new ... -
Witnessed resuscitation of adult and paediatric hospital patients: An umbrella review of the evidence
(Elsevier, 2020-08-07)Objective To examine the research evidence about whether families were allowed to witness cardiopulmonary resuscitation on hospitalised adult and paediatric patients; and the views of patients, families and health ... -
Wnt-3a and Wnt-3 differently stimulate proliferation and neurogenesis of spinal neural precursors and promote neurite outgrowth by canonical signaling
(Wiley, 2010)Wnt factors regulate neural stem cell development and neuronal connectivity. Here we investigated whether Wnt-3a and Wnt-3, expressed in the developing spinal cord, regulate proliferation and the neuronal differentiation ... -
WNT11-FZD7-DAAM1 signalling supports tumour initiating abilities and melanoma amoeboid invasion
(Nature Research, 2020)Melanoma is a highly aggressive tumour that can metastasize very early in disease progression. Notably, melanoma can disseminate using amoeboid invasive strategies. We show here that high Myosin II activity, high levels ... -
Yeast as a model system to study metabolic impact of selenium compounds
(Shared Science Publishers, 2015)Inorganic Se forms such as selenate or selenite (the two more abundant forms in nature) can be toxic in Saccharomyces cerevisiae cells, which constitute an adequate model to study such toxicity at the molecular level ... -
Yeast frataxin mutants display decreased superoxide dismutase activity crucial to promote protein oxidative damage
(Elsevier, 2010)Iron overload is involved in several pathological conditions, including Friedreich ataxia, a disease caused by decreased expression of the mitochondrial protein frataxin. In a previous study, we identified 14 proteins ... -
Zim17/Tim15 links mitochondrial iron–sulfur cluster biosynthesis to nuclear genome stability
(Oxford University Press, 2011)Genomic instability is related to a wide-range of human diseases. Here, we show that mitochondrial iron–sulfur cluster biosynthesis is important for the maintenance of nuclear genome stability in Saccharomyces cerevisiae. ... -
Zuckerman-Kuhlman-Aluja Personality Questionnaire (ZKA-PQ) and Cloninger’s Temperament and Character Inventory Revised (TCI-R): a comparative study
(Wiley-Blackwell Publishing, 2012)The aim of this study was to compare the psychometric properties (normal distribution values, reliabilities and factor structure) of the ZuckermanKuhlman-Aluja Personality Questionnaire (ZKA-PQ) and the Temperament and ... -
β-catenin signalling in Glioblastoma multiforme and Glioma-initiating cells
(Hindawi Publishing Corporation, 2012)Glioblastoma multiforme (GBM) is a commonly occurring brain tumor with a poor prognosis. GBM can develop both “de novo” or evolve from a previous astrocytoma and is characterized by high proliferation and infiltration into ...