Now showing items 1028-1047 of 1055

    • Valor social de los medicamentos para dejar de fumar. Opiniones respecto a su financiación 

      Abella i Pons, Francesc; Gil Rodríguez, Juan; Pedra Pagés, Gerard (Asociación Española de Estudio en Drogodependencias (AESED), 2020)
      Las medidas de la OMS para controlar el tabaquismo han disminuido su prevalencia, pero aumentando las diferencias entre grupos sociales. Facilitar el acceso a los medicamentos, para dejar de fumar, a los desfavorecidos ...
    • Valoración de la competencia del menor en relación con la toma de decisiones sanitarias: escala de la competencia de Lleida 

      Espejo, Mariola; Miquel Fernàndez, Eva; Esquerda i Aresté, Montse; Pifarré Paredero, Josep (Elsevier, 2011)
    • Valproic acid induces antioxidant effects in X-linked adrenoleukodystrophy 

      Fourcade, Stéphane; Ruiz, Montserrat; Guilera, Cristina; Hahnen, Eric; Brichta, Lars; Naudí i Farré, Alba; Portero Otín, Manuel; Dacremont, Georges; Cartier, Nathalie; Wanders, Ronald; Kemp, Stephan; Mandel, Jean Louis; Wirth, Brunhilde; Pamplona Gras, Reinald; Aubourg, Patrick; Pujol, Aurora (Oxford University Press, 2010)
      X-linked adrenoleukodystrophy (X-ALD) is a fatal, axonal demyelinating, neurometabolic disease. It results from the functional loss of a member of the peroxisomal ATP-binding cassette transporter subfamily D (ABCD1), ...
    • Variably protease-sensitive prionopathy presenting within ALS/FTD spectrum 

      Vicente-Pascual, Mikel; Rossi, Marcello; Gámez, Josep; Lladó, Albert; Valls, Josep; Grau-Rivera, Oriol; Ávila Polo, Rainiero; Llorens, Franc; Zerr, Inga; Ferrer, Isidre; Nos, Carlos; Parchi, Piero; Sánchez-Valle, Raquel; Gelpí, Ellen (American Neurological Association, 2018)
      We report clinico‐pathological features of a 65‐year‐old woman and a 56‐year‐old man with a 5‐year clinical history who had clinical and neuropathological characteristics of upper and lower motor neuron disease consistent ...
    • Vascular calcification induced by chronic kidney disease is mediated by an increase of 1α-hydroxylase expression in vascular smooth muscle cells 

      Torremadé Pascual, Noèlia; Bozić Stanojević, Milica; Panizo García, Sara; Barrio Vazquez, Sara; Fernandez Martín, José L.; Encinas Martín, Mario; Goltzman, David; Arcidiacono, Maria V.; Fernández i Giráldez, Elvira; Valdivielso Revilla, José Manuel (Wiley, 2016-04-01)
      Vascular calcification (VC) is a complication of chronic kidney disease that predicts morbidity and mortality. Uremic serum promotes VC, but the mechanism involved is unknown. A role for 1,25(OH)2 D3 in VC has been proposed, ...
    • Vector description of electric and hydrophobic interactions in protein homodimers 

      Mozo Villarías, Angel; Cedano, Juan; Querol, Enrique (Springer, 2016)
      This article describes the formation of homodimers from their constituting monomers, based on the rules set by a simple model of electric and hydrophobic interactions. These interactions are described in terms of the ...
    • Vigilancia de la gripe pandémica (H1N1) 2009 en Cataluña. Resultados e implicaciones 

      Godoy i García, Pere; Pumarola, Tomás; Martínez, Anna; Torner Gràcia, Núria; Rodés, Anna; Carmona, Gloria; Ciruela, Pilar; Cayla, Joan; Tortajada, Cecilia; Domínguez García, Àngela; Plasència, Antoni; Grupo de trabajo de vigilancia y control de la gripe pandémica (Ministerio de Sanidad y Consumo, 2011)
      Fundamentos. Las pandemias requieren una valoraci n de su nivel de gravedad. El objetivo fue determinar las caracter sticas de la gripe pand mica en Catalu a. Métodos. Se reali un estudio de vigilancia sobre la incidencia ...
    • Viral RNA load in plasma is associated with critical illness and a dysregulated host response in COVID‑19 

      Bermejo Martin, Jesús F.; González Rivera, Milagros; Almansa, Raquel; Micheloud, Dariela; Tedim, Ana P.; Domínguez Gil, Marta; Resino, Salvador; Martín Fernández, Marta; Murua, Pablo Ryan; Pérez García, Felipe; Tamayo Lomas, Luis; López Izquierdo, Raúl; Bustamante Munguira, Elena; Aldecoa, César; Gómez, José Manuel; Rico Feijoo, Jesús; Orduña, Antonio; Méndez, Raúl; Fernández Natal, Isabel; Megías, Gregoria; González Estecha, Montserrat; Carriedo, Demetrio; Doncel, Cristina; Jorge, Noelia; Ortega, Alicia; Fuente, Amanda de la; Campo, Félix del; Fernández Ratero, José Antonio; Trapiello, Wysali; González Jiménez, Paula; Ruiz, Guadalupe; Kelvin, Alyson A.; Toloue Ostadgavahi, Ali; Oneizat, Ruth; Ruiz, Luz María; Miguéns, Iria; Gargallo, Esther; Muñoz, Ioana; Pelegrin, Sara; Martín, Silvia; García Olivares, Pablo; Cedeño, Jamil Antonio; Ruiz Albi, Tomás; Puertas, Carolina; Berezo, Jose Ángel; Renedo, Gloria; Herrán, Rubén; Bustamante Munguira, Juan; Enríquez, Pedro; Cicuendez, Ramón; Blanco, Jesús; Abadia, Jesica; Gómez Barquero, Julia; Mamolar, Nuria; Blanca López, Natalia; Valdivia, Luis Jorge; Fernández Caso, Belén; Mantecón, María Ángeles; Motos, Anna; Fernandez Barat, Laia; Ferrer, Ricard; Barbé Illa, Ferran; Torres, Antoni; Menéndez, Rosario; Eiros, José María; Kelvin, David J. (BMC, 2020)
      Background. COVID-19 can course with respiratory and extrapulmonary disease. SARS-CoV-2 RNA is detected in respiratory samples but also in blood, stool and urine. Severe COVID-19 is characterized by a dysregulated host ...
    • Vitamin D deficiency is associated with poorer satisfaction with diabetes-related treatment and quality of life in patients with type 2 diabetes: a cross-sectional study 

      Alcubierre Calvo, Núria; Castelblanco Echavarría, Esmeralda; Martínez Alonso, Montserrat; Granado Casas, Minerva; Esquerda, Aureli; Traveset Maeso, Alicia; Martínez González, María Dolores; Franch-Nadal, Josep; Mauricio Puente, Dídac (BioMed Central, 2018-03-12)
      Background: In this cross-sectional study, we assessed the possible association of vitamin D deficiency with self-reported treatment satisfaction and health-related quality of life in patients with type 2 diabetes. Methods: ...
    • Vitamin D deficiency is associated with the presence and severity of diabetic retinopathy in type 2 Diabetes Mellitus 

      Alcubierre Calvo, Núria; Valls Marsal, Joan; Rubinat, Esther; Cao, Gonzalo; Esquerda, Aureli; Traveset Maeso, Alicia; Granado Casas, Minerva; Jurjo Campo, Carmen; Mauricio Puente, Dídac (Hindawi Publishing Corporation, 2015)
      There is very few evidences on the role of vitamin D in the development of diabetic retinopathy. The aim of the current study was to explore whether there is an association of vitamin D status and diabetic retinopathy in ...
    • Vitamin D receptor BsmI polymorphism modulates soy intake and 25-hydroxyvitamin D supplementation benefits in cardiovascular disease risk factors profile 

      Serrano Casasola, José Carlos Enrique; de Lorenzo, David; Cassanyé, Anna; Martín-Gari, Meritxell; Espinel, Alberto; Delgado, Marco Antonio; Pamplona Gras, Reinald; Portero Otín, Manuel (Springer Verlag, 2013)
      Vitamin D receptor polymorphisms may predispose that not all individuals could have benefits from the nutritional supplementation of 25-hydroxyvitamin D. Furthermore, vitamin D-related cardiovascular effects may also ...
    • Vitamin D receptor levels in colorectal cancer. Possible role of BsmI polymorphism 

      Parisi Capdevila, Eva; Reñé Espinet, Josep Maria; Cardús i Figueras, Anna; Valcheva, Petya; Piñol Felis, Carme; Valdivielso Revilla, José Manuel; Fernández i Giráldez, Elvira (Elsevier, 2008)
      A high expression of vitamin D receptor (VDR) in colorectal cancer (CRC) tumoral tissue has been related to a good prognosis and it has been proposed that it could be a good biological marker of CRC progression. Nevertheless, ...
    • Vitamin D Receptor polymorphisms and risk of enveloped virus infection: a meta-analysis 

      Laplana Lafaja, Marina; Royo Sánchez-Palencia, José Luis; Fibla Palazón, Joan (Elsevier, 2018-08-01)
      Introduction Vitamin-D plays a role regulating the immune response against to viral infection. In this sense, vitamin-D deficiency may confer increased susceptibility to enveloped virus infection such as HIV, Hepatitis, ...
    • Vitamin-D pathway genes and HIV-1 disease progression in injection drug users 

      Laplana Lafaja, Marina; Sánchez de la Torre, Manuel; Puig, Teresa; Caruz, Antonio; Fibla Palazón, Joan (Elsevier, 2014-04-21)
      Vitamin-D has pleiotropic effects on calcium and bone metabolism, cellular growth control, cell differentiation and modulation of both innate and acquired immune response. Previous studies revealed the association of ...
    • Vitamina D, receptor de la vitamina D e importancia de su activación en el paciente con enfermedad renal crónica 

      Bover, Jordi; Egido, Jesús; Fernández i Giráldez, Elvira; Praga, Manuel; Solozábal-Campos, Carlos; Torregrosa, José Vicente; Martínez-Castelao, Alberto (Sociedad Española de Nefrologia, 2015)
      El déficit de vitamina D se asocia a distintas patologías, siendo especialmente significativa con la morbimortalidad en pacientes con enfermedad renal crónica (ERC). La pérdida progresiva de la función renal conduce a ...
    • Voltage-gated calcium channel blockers deregulate macroautophagy in cardiomyocytes 

      Pushparaj, Charumathi; Das, Arindam; Purroy, Rosa; Nàger Grifo, Mireia; Herreros Danés, Judit; Pamplona Gras, Reinald; Cantí Nicolás, Carles (Elsevier, 2015)
      Voltage-gated calcium channel blockers are widely used for the management of cardiovascular diseases, however little is known about their effects on cardiac cells in vitro. We challenged neonatal ventricular cardiomyocytes ...
    • Weak Association between Skin Autofluorescence Levels and Prediabetes with an ILERVAS Cross-Sectional Study 

      Sánchez Peña, Enric; Kerkeni, M.; Hernández García, Marta; Gavaldá, Ricard; Rius, Ferran; Sauret, Ariadna; Torres, Gerard; Bermúdez López, Marcelino; Fernández i Giráldez, Elvira; Castro-Boqué, Eva; Purroy Garcia, Francisco; Mauricio Puente, Dídac; Farràs-Sallés, Cristina; Buti, Miquel; Godoy i García, Pere; Pamplona Gras, Reinald; Lecube Torelló, Albert (MDPI, 2022)
      A large body of evidence demonstrates a relationship between hyperglycemia and increased concentrations of advanced glycation end-products (AGEs). However, there is little information about subcutaneous AGE accumulation ...
    • When cholesterol is not cholesterol: a note on the enzymatic determination of its concentration in model systems containing vegetable extracts 

      Jové Font, Mariona; Serrano Casasola, José Carlos Enrique; Bellmunt i Curcó, Josepa; Cassanyé, Anna; Anglès, Neus; Reguant, Jordi; Morelló, José R.; Pamplona Gras, Reinald; Portero Otín, Manuel (BioMed Central, 2010)
      Background: Experimental evidences demonstrate that vegetable derived extracts inhibit cholesterol absorption in the gastrointestinal tract. To further explore the mechanisms behind, we modeled duodenal contents with several ...
    • Whi3 regulates morphogenesis in budding yeast by enhancing Cdk functions in apical growth 

      Colomina i Gabarrella, Neus; Ferrezuelo, Francisco; Vergés, Emili; Aldea, Martí; Garí Marsol, Eloi (Landes Bioscience, 2009)
      The Whi3 protein is associated with the endoplasmic reticulum, interacts with Cdc28, the budding-yeast Cdk, binds the mRNA of cyclin CLN3 and prevents accumulation of the Cdc28-Cln3 in the nucleus until late G1. Besides ...
    • Whi3, a developmental regulator of budding yeast, binds a large set of mRNAs functionally related to the endoplasmic reticulum 

      Colomina i Gabarrella, Neus; Ferrezuelo, Francisco; Wang, Hongyin; Aldea, Martí; Garí Marsol, Eloi (American Society for Biochemistry and Molecular Biology, 2008)
      Whi3 is an RNA-binding protein associated with the endoplasmic reticulum (ER) that binds the CLN3 mRNA and plays a key role in the efficient retention of cyclin Cln3 at the ER. In the present work, we have identified new ...