Browsing Articles publicats (IRBLleida) by Title
Now showing items 764-783 of 956
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S-PC: An e-treatment application for management of smoke-quitting patients
(Elsevier, 2014)The main objective ofthis paper is to present a new program thatfacilitates the management of people who want to quit smoking, implemented through an e-treatment software called S-PC (Smoker Patient Control). S-PC is a ... -
Saccharomyces cerevisiae as a model organism: a comparative study
(Public Library of Science (PLoS), 2011)Background: Model organisms are used for research because they provide a framework on which to develop and optimize methods that facilitate and standardize analysis. Such organisms should be representative of the living ... -
Saccharomyces cerevisiae cells have three Omega class glutathione S-transferases acting as 1-Cys thiol transferases
(Biochemical Society, 2006)The Saccharomyces cerevisiae genome encodes three proteins that Analysis of point mutants derived from wild-type Gto2 indicates display similarities with human GSTOs (Omega class glutathione that, among the three cysteine ... -
Saccharomyces cerevisiae glutaredoxin 5-deficient cells subjected to continuous oxidizing conditions are affected in the expression of specific sets of genes
(The American Society for Biochemistry and Molecular Biology, 2004)The Saccharomyces cerevisiae GRX5 gene codes for a mitochondrial glutaredoxin involved in the synthesis of iron/sulfur clusters. Its absence prevents respiratory growth and causes the accumulation of iron inside cells and ... -
Saccharomyces cerevisiae Grx6 and Grx7 are monothiol glutaredoxins associated with the early secretory pathway
(American Society for Microbiology, 2008)Saccharomyces cerevisiae Grx6 and Grx7 are two monothiol glutaredoxins whose active-site sequences (CSYS and CPYS, respectively) are reminiscent of the CPYC active-site sequence of classical dithiol glutaredoxins. Both ... -
Safety of cilostazol in peripheral artery disease: a cohort from a primary healthcare electronic database
(BioMed Central, 2018)Background: Cilostazol has been associated with spontaneous reports of cardiovascular adverse events and serious bleeding. The objective of this study is to determine the relative risk of cardiovascular adverse events ... -
Seguimiento y control de pacientes fumadores en proceso de deshabituación mediante SMS. Una experiencia en e-salud
(Asociación Española de Estudios en Drogodependencias, 2014)El consumo de tabaco continúa siendo una importante causa de morbilidad y mortalidad. El proceso terapéutico para abandonar el tabaco consiste en la desintoxicación física de la nicotina y en el mantenimiento de la abstinencia ... -
Selenite-induced cell death in Saccharomyces cerevisiae: protective role of glutaredoxins
(Society for General Microbiology, 2010)Unlike in higher organisms, selenium is not essential for growth in Saccharomyces cerevisiae. In this species, it causes toxic effects at high concentrations. In the present study, we show that when supplied as selenite ... -
Separation of rooster spermatogenic nuclei by means of centrifugal elutriation
(Wiley, 1993)By application of minor variations in the usual method of centrifugal elutriation, we have been able to separate a nuclear suspension from rooster testes. We have obtained a population of elongated or late spermatid ... -
Severe alpha-1 antitrypsin deficiency in composite heterozygotes inheriting a new splicing mutation QOMadrid
(BioMed Central, 2014)[Background]: Severe Alpha-1 Antitrypsin (AAT) deficiency is a hereditary condition caused by mutations in the SERPINA1 gene, which predisposes to lung emphysema and liver disease. It is usually related to PI*Z alleles, ... -
Sgs1’s roles in DNA end resection, HJ dissolution, and crossover suppression require a two-step SUMO regulation dependent on Smc5/6
(Cold Spring Harbor Laboratory Press, 2016)The RecQ helicase Sgs1 plays critical roles during DNA repair by homologous recombination, fromend resection to Holliday junction (HJ) dissolution. Sgs1 has both pro- and anti-recombinogenic roles, and therefore its ... -
Shadowing patients: experimentar empatía en estudiantes de medicina
(Elsevier, 2020)Introducción Shadowing patients es una de las propuestas educativas para mantener y experimentar empatía en estudiantes de Medicina. Se trata de observar, sin intervenir, a un paciente durante una visita médica. El objetivo ... -
Signal flow between CWI/TOR and CWI/RAS in budding yeast under conditions of oxidative stress and glucose starvation
(Taylor & FrancisLandes Bioscience, 2010) -
Signalling by neurotrophins and hepatocyte growth factor regulates axon morphogenesis by differential β-catenin phosphorylation
(Company of Biologist, 2008)Tyrosine phosphorylation of ß-catenin, a component of adhesion complexes and the Wnt pathway, affects cell adhesion, migration and gene transcription. By reducing ßcatenin availability using shRNA-mediated gene silencing ... -
Similarities and differences in the forebrain expression of Lhx1 and Lhx5 between chicken and mouse: insights for understanding telencephalic development and evolution
(Wiley, 2010)We compared expression of the paralogous LIM-homeodomain genes Lhx1 and Lhx5 in the developing rostral forebrain of mouse and chicken. Both genes are expressed in similar patterns in the septum, preoptic region, and ... -
Sir2 is induced by oxidative stress in a yeast model of Huntington disease and its activation reduces protein aggregation
(Elsevier, 2011)Huntington disease (HD) is a neurodegenerative disorder caused by expansion of CAG trinucleotide repeats, leading to an elongated polyglutamine sequence (polyQ) in the huntingtin protein. Misfolding of mutant polyQ ... -
SIRPB1 copy-number polymorphism as candidate quantitative trait locus for impulsive-disinhibited personality
(John Wiley & Sons, 2014-10-26)Impulsive-disinhibited personality (IDP) is a behavioral trait mainly characterized by seeking immediate gratification at the expense of more enduring or long-term gains. This trait has a major role in the development of ... -
Sit4 is required for proper modulation of the biological functions mediated by Pkc1 and the cell integrity pathway in Saccharomyces cerevisiae
(The American Society for Biochemistry and Molecular Biology, 2002)Maintenance of cellular integrity in Saccharomyces cerevisiae is carried out by the activation of the protein kinase C-mediated mitogen-activated protein kinase (PKC1-MAPK) pathway. Here we report that correct down-regulation ... -
Situación de la investigación en el cribado de cáncer de mama en España: implicaciones para la prevención
(Elsevier, 2012)Objetivo: La finalización del despliegue de los programas de detección precoz de cáncer de mama en todas las comunidades autónomas de España ha facilitado el inicio de una investigación conjunta, con información procedente ... -
SIVA-1 regulates apoptosis and synaptic function by modulating XIAP interaction with the death receptor antagonist FAIM-L
(Springer Nature, 2020)The long isoform of Fas apoptosis inhibitory molecule (FAIM-L) is a neuron-specific death receptor antagonist that modulates apoptotic cell death and mechanisms of neuronal plasticity. FAIM-L exerts its antiapoptotic action ...