Browsing Articles publicats (IRBLleida) by Title
Now showing items 690-709 of 903
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(R)-roscovitine (CYC202, Seliciclib) sensitizes SH-SY5Y neuroblastorna cells to nutlin-3-induced apoptosis
(Elsevier, 2006)In this study, we have analyzed the consequences, on several neuroblastoma cell lines, of combined treatments with (R)-roscovitine (CYC202, Seliciclib), a CDK inhibitory drug, and nutlin-3, a p53 activating drug. Both ... -
Radial and tangential migration of telencephalic somatostatin neurons originated from the mouse diagonal area
(Springer Berlin Heidelberg, 2016)The telencephalic subpallium is the source of various GABAergic interneuron cohorts that invade the pallium via tangential migration. Based on genoarchitectonic studies, the subpallium has been subdivided into four major ... -
Recommended Common Data Elements for International Research in Long-Term Care Homes: Exploring the Workforce and Staffing Concepts of Staff Retention and Turnover
(Sage, 2019)The aim of this review is to develop a common data element for the concept of staff retention and turnover within the domain of workforce and staffing. This domain is one of four core domains identified by the WE-THRIVE ... -
Recruitment of Staufen2 Enhances Dendritic Localization of an Intron-Containing CaMKIIα mRNA
(Elsevier, 2017)Regulation of mRNA localization is a conserved cellular process observed in many types of cells and organisms. Asymmetrical mRNA distribution plays a particularly important role in the nervous system, where local translation ... -
Redefining Stage I Endometrial Cancer: Incorporating Histology, a Binary Grading System, Myometrial Invasion, and Lymph Node Assessment
(BMJ Publishing Group, 2013)Objective: We propose a new staging system for stage I endometrial cancer and compare its performance to the 1988 and 2009 International Federation of Gynecology and Obstetrics (FIGO) systems. Methods: We analyzed patients ... -
Redox control and oxidative stress in yeast cells
(Elsevier, 2008)Protein structure and function can be altered by reactive oxygen species produced either by cell metabolism or by external oxidants. Although catalases, superoxide dismutases and peroxidases contribute to maintaining ... -
Redox control of yeast Sir2 activity is involved in acetic acid resistance and longevity
(Elsevier, 2019-06)Yeast Sir2 is an NAD-dependent histone deacetylase related to oxidative stress and aging. In a previous study, we showed that Sir2 is regulated by S-glutathionylation of key cysteine residues located at the catalytic domain. ... -
Redox lipidomics to better understand brain aging and function
(Elsevier, 2019)Human prefrontal cortex (PFC) is a recently evolutionary emerged brain region involved in cognitive functions. Human cognitive abilities decline during aging. Yet the molecular mechanisms that sustain the preservation or ... -
Reduction of oxidative cellular damage by overexpression of the thioredoxin TRX2 gene improves yield and quality of wine yeast dry active biomass
(BioMed Central, 2010)Background: Wine Saccharomyces cerevisiae strains, adapted to anaerobic must fermentations, suffer oxidative stress when they are grown under aerobic conditions for biomass propagation in the industrial process of active ... -
Regional Activation of Myosin II in Cancer Cells Drives Tumor Progression via a Secretory Cross-Talk with the Immune Microenvironment
(Elsevier, 2019)ROCK-Myosin II drives fast rounded-amoeboid migration in cancer cells during metastatic dissemination. Analysis of human melanoma biopsies revealed that amoeboid melanoma cells with high Myosin II activity are predominant ... -
Regulation of membrane unsaturation as antioxidant adaptive mechanism in long-lived animal species
(Phcog.Net, 2011)Oxidative stress resulting from biomolecular oxidative damage due to the imbalance between reactive species production and antioxidant response has become an universal constraint of life-history evolution in animals and ... -
Regulation of small GTPase activity by G1 cyclins
(Taylor & Francis, 2017-01-27)Together with a cyclin-dependent kinase (CDK) partner G1 cyclins control cell cycle entry by phosphorylating a number of nuclear targets and releasing a transcriptional program at the end of G1 phase. Yeast G1 cyclins also ... -
Regulation of survival motor neuron protein by the nuclear factor-kappa B pathway in mouse spinal cord motoneurons
(Springer Verlag, 2017-08-14)Survival motor neuron (SMN) protein deficiency causes the genetic neuromuscular disorder spinal muscular atrophy (SMA), characterized by spinal cord motoneuron degeneration. Since SMN protein level is critical to disease ... -
Regulation of the cell integrity pathway by rapamycin-sensitive TOR function in budding yeast
(The American Society for Biochemistry and Molecular Biology, 2002)The TOR (target of rapamycin) pathway controls cell growth in response to nutrient availability in eukary- otic cells. Inactivation of TOR function by rapamycin or nutrient exhaustion is accompanied by triggering various ... -
Regulation of the Na+/K+-ATPase Ena1 Expression by Calcineurin/Crz1 under High pH Stress: a quantitative study
(Public Library of Science, 2016)Regulated expression of the Ena1 Na+-ATPase is a crucial event for adaptation to high salt and/or alkaline pH stress in the budding yeast Saccharomyces cerevisiae. ENA1 expression is under the control of diverse signaling ... -
Relationship between aldosterone and the metabolic syndrome in patients with obstructive sleep apnea hypopnea syndrome: effect of continuous positive airway pressure treatment
(Public Library of Science, 2014)Methods: We studied 66 patients with OSAHS (33 with MS and 33 without MS) and 35 controls. The occurrence of the MS was analyzed according to the National Cholesterol Education Program Adult Treatment Panel III (NCEP ATP ... -
Relationship between empathy and the big five personality traits in a sample of Spanish adolescents
(Society for Personality Research, 2004)Empathy has been considered a central feature of our temperamental dispositions in childhood and adolescence. It plays a central role in the development of prosocial behavior and moral reasoning. However, the links between ... -
Relationship between low levels of circulating TRAIL and atheromatosis progression in patients with chronic kidney disease.
(Public Library of Science, 2018-09-11)Background: Chronic kidney disease (CKD) patients experience a high risk of cardiovascular disease (CV); however, the factors involved in CV-related morbidity and mortality in these patients have not been fully defined. ... -
Relationship of the adherence to the Mediterranean diet with health-related quality of life and treatment satisfaction in patients with type 2 diabetes mellitus: a post-hoc analysis of a cross-sectional study
(BioMed Central, 2016)Objective: The main aim of this study was to assess the association between adherence to the traditional Mediterranean diet (MedDiet) and health-related quality of life (HRQoL) and treatment satisfaction in patients ... -
Relationships between big five personality factors and values
(Society for Personality Research, 2004)An analysis of principal components showed a robust structure of three factors formed by 25 of the 30 values studied. These factors were called Social Power, Order and Benevolence values. Those factors match with some ...