Now showing items 611-630 of 1055

    • Machine learning analysis of serum biomarkers for cardiovascular risk assessment in chronic kidney disease 

      Forné Izquierdo, Carles; Cambray Carner, Serafí; Bermúdez López, Marcelino; Fernández i Giráldez, Elvira; Bozić Stanojević, Milica; Valdivielso Revilla, José Manuel (Oxford University Press, 2019)
      Background. Chronic kidney disease (CKD) patients show an increased burden of atherosclerosis and high risk of cardiovascular events (CVEs). There are several biomarkers described as being associated with CVEs, but their ...
    • Machine learning techniques for mortality prediction in critical traumatic patients: anatomic and physiologic variables from the RETRAUCI study 

      Servià Goixart, Lluís; Montserrat, Neus; Badia Castello, Mariona; Llompart-Pou, Juan Antonio; Barea-Mendoza, Jesús Abelardo; Chico-Fernández, Mario; Sánchez-Casado, Marcelino; Jiménez, José Manuel; Mayor, Dolores María; Trujillano Cabello, Javier (BMC, 2020-10-20)
      Interest in models for calculating the risk of death in traumatic patients admitted to ICUs remains high. These models use variables derived from the deviation of physiological parameters and/or the severity of anatomical ...
    • Magnesium Levels Modify the Effect of Lipid Parameters on Carotid Intima Media Thickness 

      Cambray Carner, Serafí; Ibarz Escuer, Mercedes; Bermúdez López, Marcelino; Marti Antonio, Manuel; Bozić Stanojević, Milica; Fernández i Giráldez, Elvira; Valdivielso Revilla, José Manuel (MDPI, 2020)
      Classical risk factors of atherosclerosis in the general population show paradoxical effects in chronic kidney disease (CKD) patients. Thus, low low-density lipoprotein (LDL) cholesterol levels have been associated with ...
    • Major targets of iron-induced protein oxidative damage in frataxin-deficient yeasts are magnesium-binding proteins 

      Irazusta, Verónica Patricia; Moreno Cermeño, Armando J.; Cabiscol Català, Elisa; Ros Salvador, Joaquim; Tamarit Sumalla, Jordi (Elsevier, 2008)
      Iron accumulation has been associated with several pathological conditions such as Friedreich ataxia. This human disorder is caused by decreased expression of frataxin. Iron-overload triggers oxidative stress, but the ...
    • Malignant pleural effusion: from bench to bedside 

      Psallidas, Ioannis; Kalomenidis, Ioannis; Porcel Pérez, José Manuel; Robinson, Bruce W.; Stathopoulos, Georgios T. (European Respiratory Society, 2016)
      Malignant pleural effusion (MPE) is a common but serious condition that is related with poor quality of life, morbidity and mortality. Its incidence and associated healthcare costs are rising and its management remains ...
    • Managing an online survey about influenza vaccination in primary healthcare workers 

      Toledo, Diana; Aerny, Nicole; Soldevila, Núria; Baricot, Maretva; Godoy i García, Pere; Castilla, Jesús; García-Gutiérrez, Susana; Torner Gràcia, Núria; Astray, Jenaro; Mayoral, José María; Tamames, Sonia; González-Candelas, Fernando; Martín, Vicente; Díaz, José; Domínguez García, Àngela (MDPI, 2015)
      Online surveys are increasingly used due to their speed and efficiency. The aim of this study was to analyze factors that may have contributed to the quality and speed of response of an online survey on influenza vaccination ...
    • Managing inappropriate utilization of laboratory resource 

      Cadamuro, Janne; Ibarz Escuer, Mercedes; Cornes, Michael; Nybo, Mads; Haschke Becher, Elisabeth; von Meyer, Alexander; Lippi, Giuseppe; Simundic, Ana-Maria (De Gruyter, 2019)
      Background The inappropriate use of laboratory resources, due to excessive number of tests not really necessary for patient care or by failure to order the appropriate diagnostic test, may lead to wrong, missed or delayed ...
    • Manipulating mtDNA in vivo reprograms metabolism via novel response mechanisms 

      Bahhir, Diana; Yalgin, Cagri; Ots, Liina; Järvinen, Sampsa; George, Jack; Naudí i Farré, Alba; Krama, Tatjana; Krams, Indrikis; Tamm, Mairi; Andjelković, Ana; Dufour, Eric; González de Cosar, Jose M.; Gerards, Mike; Parhiala, Mikael; Pamplona Gras, Reinald; Jacobs, Howard T.; Jõers, Priit (Public Library of Science, 2019-10-04)
      Mitochondria have been increasingly recognized as a central regulatory nexus for multiple metabolic pathways, in addition to ATP production via oxidative phosphorylation (OXPHOS). Here we show that inducing mitochondrial ...
    • Massive thrombus over an aneurysmatic left main coronary artery: Non-interventional therapy? 

      Rivera, Kristian; Fernández-Rodríguez, Diego; Zielonka, Marta; Casanova, Juan (Elsevier; Sociedade Portuguesa de Cardiologia, 2021)
    • Más allá de los parámetros lipídicos tradicionales en la enfermedad renal crónica 

      Bermúdez López, Marcelino; Betriu i Bars, M. Àngels; Valdivielso Revilla, José Manuel; Bretones del Pino, Teresa; Arroyo, David; Fernández i Giráldez, Elvira (Elsevier, 2018)
    • Measuring health-related quality of life in men with osteoporosis or osteoporotic fracture 

      Zwart, Marta; Azagra, Rafael; Encabo, Gloria; Aguyé, Amada; Roca, Genís; Güell, Sílvia; Puchol, Núria; Gene, Emili; López-Expósito, Francesc; Solà, Silvia; Ortiz, Sergio; Sancho, Pilar; Abado, Liz; Iglesias, Milagros; Pujol Salud, Jesús; Díez-Pérez, Adolf (BioMed Central, 2011)
      Background: Osteoporosis is a serious health problem that worsens the quality of life and the survival rate of individuals with this disease on account the osteoporotic fractures. Studies have long focused on women, and ...
    • Mediterranean Diet and Healthy Eating in Subjects with Prediabetes from the Mollerussa Prospective Observational Cohort Study 

      Falguera, Mireia; Catelblanco, Esmeralda; Rojo López, Marina Idalia; Vilanova Fillat, María Belén; Real, Jordi; Alcubierre Calvo, Núria; Miró, Neus; Molló Inesta, Àngels; Mata Cases, Manel; Franch-Nadal, Josep; Granado Casas, Minerva; Mauricio Puente, Dídac (MDPI, 2021)
      We aimed to assess differences in dietary patterns (i.e., Mediterranean diet and healthy eating indexes) between participants with prediabetes and those with normal glucose tolerance. Secondarily, we analyzed factors related ...
    • Melanoma transplants in “green” mice: Fluorescent cells in tumors are not equivalent to host-derived cells 

      García-Olmo, Dolores C.; Picazo, María G.; García-Olmo, Damián (Elsevier, 2018)
      Background: To examine the usefulness of green fluorescent protein (GFP) mice for studying the interactions between normal cells and tumor cells in a host, we used a melanoma model in such “green” mice [C57BL/6-Tg(CAG-EGFP)1Osb ...
    • Membrane lipid unsaturation as physiological adaptation to animal longevity 

      Naudí i Farré, Alba; Jové Font, Mariona; Ayala Jové, Ma. Victoria (Maria Victoria); Portero Otín, Manuel; Barja, Gustavo; Pamplona Gras, Reinald (Frontiers Media, 2013)
      The appearance of oxygen in the terrestrial atmosphere represented an important selective pressure for ancestral living organisms and contributed toward setting up the pace of evolutionary changes in structural and ...
    • Meningococcal disease and vaccines: still many questions and some answers 

      Godoy i García, Pere; Castilla, Jesús; Astray, Jenaro; Tuells, José; Barrabeig i Fabregat, Irene; Domínguez, Ángela (Sociedad Española de Salud Pública y Administración Sanitaria, 2020)
    • Metabolic adaptations in spontaneously immortalized PGC-1α knock-out mouse embryonic fibroblasts increase their oncogenic potential 

      Prieto, Ignacio; Rubio Alarcón, Carmen; García-Gómez, Raquel; Berdún Hernández, Rebeca; Urgel, Tamara; Portero Otín, Manuel; Pamplona Gras, Reinald; Martínez-Ruiz, Antonio; Ruiz-Sanz, José Ignacio; Ruiz-Larrea, M. Begoña; Jové Font, Mariona; Cerdán, Sebastián; Monsalve, María (Elsevier, 2020-01-01)
      PGC-1α controls, to a large extent, the capacity of cells to respond to changing nutritional requirements and energetic demands. The key role of metabolic reprogramming in tumor development has highlighted the potential ...
    • Metabolic remodeling in frataxin-deficient yeast is mediated by Cth2 and Adr1 

      Moreno Cermeño, Armando J.; Alsina Obiols, David; Cabiscol Català, Elisa; Tamarit Sumalla, Jordi; Ros Salvador, Joaquim (Elsevier, 2013)
      Frataxin is a mitochondrial protein involved in iron metabolism whose deficiency in humans causes Friedreich ataxia. We performed transcriptomic and proteomic analyses of conditional Yeast Frataxin Homologue (Yfh1) mutants ...
    • Metabolomic and lipidomic profiling identifies the role of the RNA editing pathway in endometrial carcinogenesis 

      Altadill, Tatiana; Dowdy, Tyrone M.; Gill, Kirandeep; Reques, Armando; Menon, Smrithi S.; Moiola, Cristian P.; Lopez-Gil, Carlos; Coll, Eva; Matias-Guiu, Xavier; Cabrera, Silvia; Garcia, Angel; Reventós, Jaume; W. Byers, Stephen; Gil-Moreno, Antonio; Cheema, Amrita K.; Colás, Eva (Nature Publishing Group, 2017)
      Endometrial cancer (EC) remains the most common malignancy of the genital tract among women in developed countries. Although much research has been performed at genomic, transcriptomic and proteomic level, there is still ...
    • Metabolomics predicts neuroimaging characteristics of transient ischemic attack patients 

      Purroy Garcia, Francisco; Cambray Carner, Serafí; Mauri-Capdevila, Gerard; Jové Font, Mariona; Sanahuja Montesinos, Jordi; Farré, Joan; Benabdelhak Abbou, Ikram; Molina Seguin, Jessica; Colàs Campàs, Laura; Begué Gómez, Robert; Gil, M. Isabel; Pamplona Gras, Reinald; Portero Otín, Manuel (Elsevier, 2016)
      Background: Neuroimaging is essential for the diagnosis and prognosis of transient ischemic attack (TIA). The discovery of a plasmatic biomarker related to neuroimaging findings is of enormous interest because, despite ...
    • Metabolomics predicts stroke recurrence after transient ischemic attack 

      Jové Font, Mariona; Mauri-Capdevila, Gerard; Suárez-Luis, Idalmis; Cambray Carner, Serafí; Sanahuja Montesinos, Jordi; Quilez Martínez, Alejandro; Farré, Joan; Benabdelhak Abbou, Ikram; Pamplona Gras, Reinald; Portero Otín, Manuel; Purroy Garcia, Francisco (American Academy of Neurology, 2015)
      Objective: To discover, by using metabolomics, novel candidate biomarkers for stroke recurrence (SR) with a higher prediction power than present ones. Methods: Metabolomic analysis was performed by liquid chromatography ...