Now showing items 483-502 of 1133

    • Ganancia de peso durante el confinamiento por la COVID-19; encuesta de la Sociedad Española de Obesidad 

      López de la Torre, Martín; Bellido, Diego; Monereo, Susana; Lecube Torelló, Albert; Sánchez Peña, Enric; Tinahones, Francisco José (Sociedad Española de Cirugía de Obesidad y Metabólica y Sociedad Española para el Estudio de la Obesidad, 2020-11-01)
      La obesidad, después de la edad, es el principal factor de mal pronóstico durante la infección por la COVID-19. El confinamiento al que la población española ha sido expuesta durante varias semanas puede ser una causa de ...
    • GATA6 Activates Wnt Signaling in Pancreatic Cancer by Negatively Regulating the Wnt Antagonist Dickkopf-1 

      Zhong, Yi; Wang, Zheng; Fu, Baojin; Pan, Fan; Yachida, Shinichi; Dhara, Mousumi; Albesiano, Emilia; Li, Li; Naito, Yoshiki; Vilardell, Felip; Cummings, Christopher; Martinelli, Paola; Li, Ang; Yonescu, Raluca; Ma, Qingyong; Griffin, Constance A.; Real, Francisco X.; Iacobuzio-Donahue, Christine A. (Public Library of Science, 2011)
      Pancreatic ductal adenocarcinoma (PDAC) is a highly lethal disease characterized by late diagnosis and treatment resistance. Recurrent genetic alterations in defined genes in association with perturbations of developmental ...
    • Gender differences between the emotions experienced and those identified in an urban space, based on heart rate variability 

      Paül i Agustí, Daniel; Guilera Lladós, Teresa; Guerrero i Lladós, Montse (Elsevier, 2022-09-27)
      The effects that urban spaces can have on people have been analysed by various means. However, in the majority of cases, such analyses have been carried out after the event and based on memories of what was experienced. ...
    • Gene expression and regulatory factors of the mechanistic target of rapamycin (mTOR) complex 1 predict mammalian longevity 

      Mota Martorell, Natàlia; Jové Font, Mariona; Pradas Barriga, Irene; Berdún Hernández, Rebeca; Sanchez, Isabel; Naudí i Farré, Alba; Garí Marsol, Eloi; Barja, Gustavo; Pamplona Gras, Reinald (Springer, 2020-08-01)
      Maximum longevity (ML) varies significantly across animal species, but the underlying molecular mechanisms remain poorly understood. Recent studies and omics approaches suggest that phenotypic traits of ML could to converge ...
    • Genetic and experimental evidence supports the continuum of the central extended amygdala and a mutiple embryonic origin of its principal neurons 

      Bupesh, Munisamy; Abellán Ródenas, Antonio; Medina Hernández, Loreta Mª (Wiley, 2011)
      The central extended amygdala is the major output center for telencephalic control of ingestion, fear responses, stress, and anxiety. In spite of the abundant data supporting the similarity in neurochemistry, connections, and ...
    • Genetic associations of the vitamin D and antiviral pathways with natural resistance to HIV-1 infection are influenced by interpopulation variability 

      Aguilar-Jiménez, Wbeimar; Zapata, Wildeman; Rivero-Juárez, Antonio; Pineda, Juan Antonio; Laplana Lafaja, Marina; Taborda, Natalia A.; Biasin, Mara; Clerici, Mario; Caruz, Antonio; Fibla Palazón, Joan; Rugeles, Maía T. (Elsevier, 2019)
      Vitamin D (VitD) may modulate anti-HIV-1 responses modifying the risk to acquire the HIV-1-infection. We performed a nested case-control exploratory study involving 413 individuals; HIV-1-exposed seropositives (cases) and ...
    • Genetic identification of the central nucleus and other components of the central extended amygdala in chicken during development 

      Vicario Andrade, Alba; Abellán Ródenas, Antonio; Desfilis, Ester; Medina Hernández, Loreta Mª (Frontiers Media S.A., 2014-09-10)
      In mammals, the central extended amygdala shows a highly complex organization, and is essential for animal survival due to its implication in fear responses. However, many aspects of its evolution are still unknown, and ...
    • Genetic structure of the Spanish population 

      Gayán, Javier; Galan, José J.; González-Pérez, Antonio; Sáez, María Eugenia; Martínez-Larrad, María Teresa; Zabena, Carina; Rivero, M. Carmen; Salinas, Ana; Ramírez-Lorca, Reposo; Morón, Francisco J.; Royo Sánchez-Palencia, José Luis; Moreno-Rey, Concha; Velasco, Juan; Carrasco, José M.; Molero, Eva; Ochoa, Carolina; Ochoa, María Dolores; Gutiérrez, Marta; Reina, Mercedes; Pascual, Rocío; Romo-Astorga, Alejandro; Susillo-González, Juan Luis; Vázquez, Enrique; Real, Luis M.; Ruiz, Agustín; Serrano-Ríos, Manuel (BioMed Central, 2010-05-25)
      Background Genetic admixture is a common caveat for genetic association analysis. Therefore, it is important to characterize the genetic structure of the population under study to control for this kind of potential bias. ...
    • Genetic Testing to Predict Weight Loss and Diabetes Remission and Long-Term Sustainability after Bariatric Surgery: A Pilot Study 

      Ciudin, Andreea; Fidilio, Enzamaria; Ortiz, Angel; Pich, Sara; Salas, Eduardo; Mesa, Jordi; Hernández, Cristina; Simó-Servat, Olga; Lecube Torelló, Albert (MDPI, 2019)
      Introduction: The aim of this pilot study was to assess genetic predisposition risk scores (GPS) in type 2 diabetic and non-diabetic patients in order to predict the better response to bariatric surgery (BS) in terms of ...
    • Genetic variability in geographic populations of the natterjack toad (Bufo calamita) 

      Oromí Farrús, Neus; Richter-Boix, A; Sanuy i Castells, Delfí; Fibla Palazón, Joan (Wiley Open Access, 2012)
      Across altitudinal and latitudinal gradients, the proportion of suitable habitats varies, influencing the individual dispersal that ultimately can produce differentiation among populations. The natterjack toad (Bufo ...
    • Genetic Variants in PGE2 Receptors Modulate the Risk of Nephrosclerosis and Clinical Outcomes in These Patients 

      González, Luz María; Robles, Nicolás Roberto; Mota Zamorano, Sonia; Valdivielso Revilla, José Manuel; López Gómez, Juan; Gervasini, Guillermo (MDPI, 2021)
      Prostaglandin E2 (PGE2) is a major actor mediating renal injury. We aimed to determine genetic variability in the genes coding for its receptors (PTGER1-4) and study associations with nephrosclerosis risk and clinical ...
    • Genetics Variants in the Epoxygenase Pathway of Arachidonic Metabolism Are Associated with Eicosanoids Levels and the Risk of Diabetic Nephropathy 

      Mota Zamorano, Sonia; Robles, Nicolás Roberto; González, Luz María; Valdivielso Revilla, José Manuel; López Gómez, Juan; Cancho, Bárbara; García Pino, Guadalupe; Gervasini, Guillermo (MDPI, 2021)
      Genes in the epoxygenase pathway of arachidonic acid metabolism leading to vasoactive eicosanoids, mainly 20-hydroxyeicosatetraenoic (20-HETE) and epoxyeicosatrienoic (EETs) acids, have been related to glucose-induced renal ...
    • Genetics: Is LADA just late onset type 1 diabetes? 

      Hernández García, Marta; Nóvoa Medina, Yeray; Faner, R.; Palou, E.; Esquerda, Aureli; Castelblanco Echavarría, Esmeralda; Wägner, Ana María; Mauricio Puente, Dídac (Frontiers Media, 2022)
      Background: There is a controversy regarding Latent Autoimmune Diabetes in Adults (LADA) classification and whether it should be considered a slowly progressing form of type 1 (T1) diabetes (DM) or a distinct type of DM ...
    • Genoarchitecture of the extended amygdala in zebra finch, and expression of FoxP2 in cell corridors of different genetic profile 

      Vicario Andrade, Alba; Mendoza, Ezequiel; Abellán Ródenas, Antonio; Scharff, Constance; Medina Hernández, Loreta Mª (Springer Verlag, 2016)
      We used a battery of genes encoding transcription factors (Pax6, Islet1, Nkx2.1, Lhx6, Lhx5, Lhx9, FoxP2) and neuropeptides to study the extended amygdala in developing zebra finches. We identified different components of ...
    • Genome Wide Meta-Analysis identifies common genetic signatures shared by heart function and Alzheimer’s disease 

      Sáez, María Eugenia; González-Pérez, Antonio; Hernández-Olasagarre, B.; Beà Tàrrega, Aida; Moreno-Grau, S.; de Rojas, Itziar; Monté-Rubio, G.; Orellana, Adelina; Valero, S.; Comella i Carnicé, Joan Xavier; Sanchis, Daniel; Ruiz, Agustín (Nature Publishing Group, 2019)
      Echocardiography has become an indispensable tool for the study of heart performance, improving the monitoring of individuals with cardiac diseases. Diverse genetic factors associated with echocardiographic measures have ...
    • Genome-Wide Association Study of VKORC1 and CYP2C9 on acenocoumarol dose, stroke recurrence and intracranial haemorrhage in Spain 

      Cullell, Natalia; Carrera, Caty; Muiño, Elena; Torres-Aguila, Nuria-Paz; Cárcel-Márquez, Jara; González-Sánchez, Jonathan; Gallego Fabrega, Cristina; Molina, Jessica; Besora, Sarah; Sotoca, Javier; Buongiorno, Maria-Teresa; Jiménez-Conde, Jordi; Giralt-Steinhauer, Eva; de Torres-Chacón, Reyes; Montaner, Joan; Mancha, Fernando; Cabezas, Juan A.; Martí Fàbregas, Joan; Prats Sánchez, Luis; Camps Renom, Pol; Purroy Garcia, Francisco; Cambray Carner, Serafí; Freijo, María del Mar; Vives-Bauzá, Cristòfol; Tur, Silvia; Font, Maria-Àngels; López-Cancio, Elena; Hernandez-Perez, Maria; Obach, Victor; Calleja, Ana; Arenillas, Juan F.; Rodríguez-Yáñez, Manuel; Castillo, José; Sobrino, Tomas; Fernández-Cádenas, Israel; Krupinski, Jerzy (Nature Publishing Group, 2020)
      Acenocoumarol is an oral anticoagulant with significant interindividual dose variations. Variants in CYP2C9 and VKORC1 have been associated with acenocoumarol maintenance dose. We analysed whether any of the 49 polymorphisms ...
    • Genome-wide methylation profiling reveals Zinc finger protein 516 (ZNF516) and FK-506-binding protein 6 (FKBP6) promoters frequently methylated in cervical neoplasia, associated with HPV status and ethnicity in a Chilean population 

      Brebi, Priscilla; Maldonado, Leonel; Noordhuis, Maartje G.; Ili, Carmen; Leal, Pamela; Garcia, Patricia; Brait, Mariana; Ribas i Fortuny, Judit; Michailidi, Christina; Perez, Jimena; Soudry, Ethan; Tapia, Oscar; Guzman, Pablo; Muñoz, Sergio; Van Neste, Leander; Van Criekinge, Wim; Irizarry, Rafael; Sidransky, David; Roa, Juan C.; Guerrero-Preston, Rafael (Taylor & Francis, 2014-02-01)
      Cervical cancer is a major health concern among women in Latin America due to its high incidence and mortality. Therefore, the discovery of molecular markers for cervical cancer screening and triage is imperative. The aim ...
    • Genome-wide transcriptional profiling of pulmonary functional sequelae in ARDS- secondary to SARS-CoV-2 infection 

      García Hidalgo, María Coronada; Peláez, Rafael; González, Jessica; Santisteve, Sally; Benítez, Iván; Molinero, Marta; Perez-Pons, Manel; Belmonte, Thalía; Torres, Gerard; Moncusí Moix, Anna; Gort Paniello, Clara; Aguilà, Maria; Seck, Faty; Carmona, Paola; Caballero, Jesús; Barberà, Carme; Ceccato, Adrián; Fernández Barat, Laia; Ferrer, Ricard; Garcia-Gasulla, Dario; Lorente, José Ángel; Menéndez, Rosario; Motos, Anna; Peñuelas, Oscar; Riera, Jordi; Bermejo Martin, Jesús F.; Torres, Antoni; Barbé Illa, Ferran; de Gonzalo Calvo, David; Larrayoz, Ignacio M. (Elsevier, 2022)
      Background: Up to 80% of patients surviving acute respiratory distress syndrome (ARDS) secondary to SARS-CoV- 2 infection present persistent anomalies in pulmonary function after hospital discharge. There is a limited ...
    • Genomic Characterization of Host Factors Related to SARS-CoV-2 Infection in People with Dementia and Control Populations: The GR@ACE/DEGESCO Study 

      de Rojas, Itziar; Hernández, Isabel; Montrreal, Laura; Quintela, Inés; Calero, Miguel; Royo, Jose Luís; Huerto Vilas, Raquel; González Pérez, Antonio; Franco Macías, Emilio; Macías, Juan; Menéndez González, Manuel; Frank García, Ana; Diez Fairen, Mónica; Lage, Carmen; García Madrona, Sebastián; Aguilera, Nuria; García González, Pablo; Puerta, Raquel; Sotolongo Grau, Oscar; Alonso Lana, Silvia; Rábano, Alberto; Arias Pastor, Alfonso; Pastor, Ana Belén; Corma Gómez, Anaïs; Martín Montes, Ángel; Martínez Rodríguez, Carmen; Buiza Rueda, Dolores; Rodríguez Rodríguez, Eloy; Álvarez, Ignacio; Rosas Allende, Irene; Pineda, Juan A.; Bernal Sánchez-Arjona, María; Fernández Fuertes, Marta; Mendoza, Silvia; Del Ser, Teodoro; García Ribas, Guillermo; Sánchez Juan, Pascual; Pastor, Pau; Bullido, María J.; Álvarez, Victoria; Real, Luis M.; Mir, Pablo; Piñol Ripoll, Gerard; García Alberca, Jose María; Medina, Miguel; Orellana, Adelina; Butler, Chris R.; Marquié, Marta; Sáez, María Eugenia; Carracedo, Angel; Tárraga, Lluís; Boada, Mercè; Ruiz, Agustín (MDPI, 2021)
      Emerging studies have suggested several chromosomal regions as potential host genetic factors involved in the susceptibility to SARS-CoV-2 infection and disease outcome. We nested a COVID-19 genome-wide association study ...
    • Genomic profiling of primary and recurrent adult granulosa cell tumors of the ovary 

      Gatius Calderó, Sònia; Cruz Paula, Arnaud Da; Silva, Edaise M. da; Segura, Sheila E.; Pareja, Fresia; Bi, Rui; Selenica, Pier; Kim, Sarah H.; Ferrando, Lorenzo; Vahdatinia, Mahsa; Soslow, Robert A.; Vidal, August; Przybycin, Christopher G.; Abu-Rustum, Nadeem R.; Matias-Guiu, Xavier; Rubin, Brian P.; Reis-Filho, Jorge S.; DeLair, Deborah F.; Weigelt, Britta (2020)
      Adult-type granulosa cell tumor (aGCT) is a rare malignant ovarian sex cord-stromal tumor, harboring recurrent FOXL2 c.C402G/p.C134W hotspot mutations in 97% of cases. These tumors are considered to have a favorable ...