Now showing items 270-289 of 1084

    • Dapagliflozin plus exenatide on patients with type 2 diabetes awaiting bariatric surgery in the DEXBASU study 

      López Cano, Carolina; Santos, María Dolores; Sánchez Peña, Enric; Martí, Raquel; Bueno Díez, Marta; Gutiérrez Carrasquilla, Liliana; Lecube Torelló, Albert (Nature Research, 2022)
      The glucagon-like peptide-1 receptor agonist family together with the renal sodium/glucose cotransporter-2 inhibitors have garnered interest as potential therapeutic agents for subjects with type 2 diabetes and obesity. ...
    • Daptomycin plus fosfomycin versus daptomycin alone for methicillin-resistant staphylococcus aureus bacteremia and endocarditis: a randomized clinical trial 

      Pujol, Miquel; Miró, José María; Shaw, Evelyn; Aguado, Jose María; San Juan, Rafael; Puig Asensio, Mireia; Pigrau, Carles; Calbo Sebastian, Esther; Montejo, Miguel; Rodríguez Álvarez, Regino; García Pais, María Jose; Pintado, Vicente; Escudero Sánchez, Rosa; López Contreras, Joaquín; Morata, Laura; Montero, Milagros; Andrés, Marta; Pasquau, Juan; Arenas, María del Mar; Padilla, Belén; Murillas, Javier; Jover, Alfredo; López Cortes, Luis Eduardo; García Pardo, Graciano; Gasch, Oriol; Videla, Sebastian; Hereu, Pilar; Tebé, Cristian; Pallarès, Natalia; Sanllorente, Mireia; Domínguez, María Ángeles; Càmara, Jordi; Ferrer, Anna; Padullés, Ariadna; Cuervo, Guillermo; Carratalà, Jordi (Oxford University Press; Infectious Diseases Society of America, 2021)
      Background. We aimed to determine whether daptomycin plus fosfomycin provides higher treatment success than daptomycin alone for methicillin-resistant Staphylococcus aureus (MRSA) bacteremia and endocarditis.Methods. A ...
    • Database constraints applied to metabolic pathway reconstruction tools 

      Vilaplana Mayoral, Jordi; Solsona Tehàs, Francesc; Teixidó Torrelles, Ivan; Usié Chimenos, Anabel; Karathia, Hiren; Alves, Rui; Mateo Fornés, Jordi (Hindawi Publishing Corporation, 2014)
      Our group developed two biological applications, Biblio-MetReS and Homol-MetReS, accessing the same database of organisms with annotated genes. Biblio-MetReS is a data-mining application that facilitates the reconstruction ...
    • De novo assembly of the Brown trout (Salmo trutta m. fario) brain and muscle transcriptome: transcript annotation, tissue differential expression profile and SNP discovery 

      Fibla Palazón, Joan; Oromí Farrús, Neus; Pascual Pons, Mariona; Royo Sánchez-Palencia, José Luis; Palau, Antoni; Fibla, M. (BMC, 2020-11-02)
      Objectives: The Brown trout is a salmonid species with a high commercial value in Europe. Life history and spawning behaviour include resident (Salmo trutta m. fario) and migratory (Salmo trutta m. trutta) ecotypes. The ...
    • Decrease in sleep depth is associated with higher cerebrospinal fluid neurofilament light levels in patients with Alzheimer's disease 

      Targa, Adriano; Dakterzada, Farida; Benítez, Iván; López Ortega, Ricard; Pujol, Montserrat; Dalmases, Mireia; Arias Pastor, Alfonso; Sánchez de la Torre, Manuel; Zetterberg, Henrik; Blennow, Kaj; Pamplona Gras, Reinald; Jové Font, Mariona; Barbé Illa, Ferran; Piñol Ripoll, Gerard (Oxford University Press, 2021)
      STUDY OBJECTIVES: The majority of studies investigating the association between sleep and Alzheimer's disease (AD) biomarkers have been performed in healthy participants. Our objective was to investigate the association ...
    • Decreased quality of live and treatment satisfaction in patients with latent autoinmune diabetes of the adult 

      Granado Casas, Minerva; Martínez Alonso, Montserrat; Alcubierre Calvo, Núria; Ramírez-Morros, Anna; Hernández García, Marta; Castelblanco Echavarría, Esmeralda; Torres Puig-gros, Joan; Mauricio Puente, Dídac (PeerJ, 2017-10-18)
      Objectives. Our main aim was to assess the quality of life (QoL) and treatment satisfaction (TS) of subjects with LADA (latent autoimmune diabetes of the adult) and compare these measures with those of patients with other ...
    • Deficient endoplasmic reticulum-mitochondrial phosphatidylserine transfer causes liver disease 

      Hernández-Alvarez, María Isabel; Sebastián, David; Vives, Sara; Ivanova, Sa ka; Bartoccioni, Paola; Kakimoto, Pamela; Plana, Natalia; Veiga, Sónia R.; Hernández, Vanessa; Vasconcelos, Nuno; Gopalacharyulu, Peddinti; Adrover, Anna; Jové Font, Mariona; Pamplona Gras, Reinald; Berenguer-Llergo, Antonio; Gordaliza, Isabel; Calvo, Enrique; Cabré, Noemí; Castro, Rui; Kuzmanic, Antonija; Boutant, Marie; Sala, David; Hyotylainen, Tuulia; Oresic, Matej; Fort, Joana; Errasti-Murugarren, Ekaitz; Orozco, Modesto; Joven, Jorge; Cantó, Carles; Palacin, Manuel; Fernández-Veledo, Sonia; Vendrell, Joan; Zorzano, Antonio (Elsevier, 2019-05-02)
      Non-alcoholic fatty liver is the most common liver disease worldwide. Here, we show that the mitochondrial protein mitofusin 2 (Mfn2) protects against liver disease. Reduced Mfn2 expression was detected in liver biopsies ...
    • Depletion of oxidative and endoplasmic reticulum stress regulators in Pick disease 

      Ilieva, Ekaterina V.; Naudí i Farré, Alba; Kichev, Anton Vladimirov; Ferrer, Isidre; Pamplona Gras, Reinald; Portero Otín, Manuel (Elsevier, 2010)
      Both oxidative and endoplasmic reticulum (ER) stress is associated with multiple neurodegenerative, age-related diseases. The rare disorder Pick disease (PiD) shares some pathological hallmarks of other neurodegenerative ...
    • Depression and Apathy After Transient Ischemic Attack or Minor Stroke: Prevalence, Evolution and Predictors 

      Carnes Vendrell, Anna; Deus Yela, Juan; Molina Seguin, Jessica; Pifarré Paredero, Josep; Purroy Garcia, Francisco (Nature Research, 2019)
      Few previous studies have focused on affective impairment after transient ischemic attack (TIA) and/or minor stroke. The aim was to establish the prevalence, evolution and predictors of post-stroke depression (PSD) and ...
    • Dermatofibrosarcoma protuberans sobre cicatriz de apendicectomía 

      Veà Jódar, Àlvar; Aguayo Ortiz, Rafael; Soria, Xavier; Sanmartín Novell, Verònica; Casanova i Seuma, Josep M. (Josep Manel) (Elsevier, 2015)
      El dermatofibrosarcoma protuberans (DFSP) es un tumor cutáneo relativamente raro, con una incidencia aproximada de 4 casos por cada millón de habitantes y año1,2. Ahora bien, es el sarcoma cutáneo más frecuente, ...
    • Dermatological Manifestations in the Intensive Care Unit: A Practical Approach 

      Badia Castello, Mariona; Casanova i Seuma, Josep M. (Josep Manel); Servià Goixart, Lluís; Montserrat, Neus; Codina, Jordi; Trujillano Cabello, Javier (Hindawi, 2020-09-26)
      Dermatological problems are not usually related to intensive medicine because they are considered to have a low impact on the evolution of critical patients. Despite this, dermatological manifestations (DMs) are relatively ...
    • Descriptive study of association between quality of care and empathy and burnout in primary care 

      Yuguero Torres, Oriol; Marsal Mora, Josep Ramon; Buti, Miquel; Esquerda i Aresté, Montse; Soler González, Jorge (BioMed Central, 2017)
      The doctor-patient relationship is a crucial aspect of primary-care practice Research on associations between quality of care provision and burnout and empathy in a primary care setting could improve this relationship.
    • Design and Validation of a Computer Application for Diagnosis of Shoulder Locomotor System Pathology 

      Bigordà Sagué, Albert; Trujillano Cabello, Javier; Ariza Carrió, Gemma; Campoy Guerrero, Carme (Korean Society of Medical Informatics, 2019)
      Objectives: To design and validate a computer application for the diagnosis of shoulder locomotor system pathology. Meth-ods: The first phase involved the construction of the application using the Delphi method. In the ...
    • Design and Validation of an Instrument To Measure a Minor's Maturity When Faced with Health Decisions 

      Miquel Fernàndez, Eva; Esquerda i Aresté, Montse; Real, Jordi; Espejo, Mariola; Pifarré Paredero, Josep (Springer, 2019)
      Decision-making capacity in children and adolescents in healthcare requires thorough assessment: the minor's maturity, understanding of the decision, risk of the situation and contextual factors needs to be explored. The ...
    • Design, construction, and implementation of an online platform for patients with type 1 diabetes: EncoDiab 

      Alvarado-Martel, Dàcil; Cañas Ortiz, Francesca; Velasco, Rebeca; Alcubierre Calvo, Núria; López-Ríos, Laura; Rius, Ferran; Nóvoa, Francisco Javier; Carrillo, Armando; Hernández García, Marta; Wägner, Ana María; Mauricio Puente, Dídac (Dove Medical Press, 2015)
      Purpose: The purpose of this study was to develop, build, and implement a virtual platform equipped with practical tools, relevant contents, and communication rooms, with the aim of facilitating patients’ self-management ...
    • Design, optimization and validation of genes commonly used in expression studies on DMH/AOM rat colon carcinogenesis model 

      Bars-Cortina, David; Riera-Escamilla, Antoni; Gou, Gemma; Piñol Felis, Carme; Motilva Casado, Mª José (PeerJ, 2019-01-29)
      Colorectal cancer (CRC), also known as colon cancer, is the third most common form of cancer worldwide in men and the second in women and is characterized by several genetic alterations, among them the expression of several ...
    • Detection of Severe Obstructive Sleep Apnea through voice analysis 

      Solé-Casals, Jordi; Munteanu, Cristian; Capdevila Martín, Oriol; Barbé Illa, Ferran; Durán-Cantolla, Joaquín; Queipo, Carlos; Amilibia, Jose (Elsevier, 2014)
      This paper deals with the potential and limitations of using voice and speech processing to detect Obstructive Sleep Apnea (OSA). An extensive body of voice features has been extracted from patients who present various ...
    • Determinants of sensitivity to radiotherapy in endometrial cancer 

      Sorolla Bardají, Maria Alba; Parisi Capdevila, Eva; Sorolla Bardají, Anabel (MDPI, 2020)
      Radiotherapy is one of the cornerstone treatments for endometrial cancer and has successfully diminished the risk of local recurrences after surgery. However, a considerable percentage of patients suffers tumor relapse due ...
    • Development and evolution of the pallium 

      Medina Hernández, Loreta Mª; Abellán Ródenas, Antonio (Elsevier, 2009)
      The neocortex is the most representative and elaborated structure of the mammalian brain and is related to the achievement of complex cognitive capabilities, which are disturbed following malformation or lesion. Searching ...
    • Development and validation of a sample entropy-based method to identify complex patient-ventilator interactions during mechanical ventilation 

      Sarlabous Uranga, Leonardo; Aquino Esperanza, Jose; Magrans, Rudys; de Haro, Candelaria; López-Aguilar, Josefina; Subirà, Carles; Batlle, Montserrat; Rué i Monné, Montserrat; Gomà Fernández, Gemma; Ochagavía, Ana; Fernández, Rafael; Blanch, Lluís (Scientific Reports, 2020)
      Patient-ventilator asynchronies can be detected by close monitoring of ventilator screens by clinicians or through automated algorithms. However, detecting complex patient-ventilator interactions (CP-VI), consisting of ...