Now showing items 238-257 of 935

    • Database constraints applied to metabolic pathway reconstruction tools 

      Vilaplana Mayoral, Jordi; Solsona Tehàs, Francesc; Teixidó Torrelles, Ivan; Usié Chimenos, Anabel; Karathia, Hiren; Alves, Rui; Mateo Fornés, Jordi (Hindawi Publishing Corporation, 2014)
      Our group developed two biological applications, Biblio-MetReS and Homol-MetReS, accessing the same database of organisms with annotated genes. Biblio-MetReS is a data-mining application that facilitates the reconstruction ...
    • De novo assembly of the Brown trout (Salmo trutta m. fario) brain and muscle transcriptome: transcript annotation, tissue differential expression profile and SNP discovery 

      Fibla Palazón, Joan; Oromí Farrús, Neus; Pascual Pons, Mariona; Royo Sánchez-Palencia, José Luis; Palau, Antoni; Fibla, M. (BMC, 2020-11-02)
      Objectives: The Brown trout is a salmonid species with a high commercial value in Europe. Life history and spawning behaviour include resident (Salmo trutta m. fario) and migratory (Salmo trutta m. trutta) ecotypes. The ...
    • Decrease in sleep depth is associated with higher cerebrospinal fluid neurofilament light levels in patients with Alzheimer's disease 

      Targa, Adriano; Dakterzada, Faride; Benítez, Iván; López, Ricard; Pujol, Montserrat; Dalmases, Mireia; Arias, Alfonso; Sánchez de la Torre, Manuel; Zetterberg, Henrik; Blennow, Kaj; Pamplona Gras, Reinald; Jové, Mariona; Barbé Illa, Ferran; Piñol Ripoll, Gerard (Oxford University Press, 2021)
      STUDY OBJECTIVES: The majority of studies investigating the association between sleep and Alzheimer's disease (AD) biomarkers have been performed in healthy participants. Our objective was to investigate the association ...
    • Decreased quality of live and treatment satisfaction in patients with latent autoinmune diabetes of the adult 

      Granado Casas, Minerva; Martínez Alonso, Montserrat; Alcubierre Calvo, Núria; Ramírez-Morros, Anna; Hernández, Marta; Castelblanco Echavarría, Esmeralda; Torres Puig-gros, Joan; Mauricio Puente, Dídac (PeerJ, 2017-10-18)
      Objectives. Our main aim was to assess the quality of life (QoL) and treatment satisfaction (TS) of subjects with LADA (latent autoimmune diabetes of the adult) and compare these measures with those of patients with other ...
    • Deficient endoplasmic reticulum-mitochondrial phosphatidylserine transfer causes liver disease 

      Hernández-Alvarez, María Isabel; Sebastián, David; Vives, Sara; Ivanova, Sa ka; Bartoccioni, Paola; Kakimoto, Pamela; Plana, Natalia; Veiga, Sónia R.; Hernández, Vanessa; Vasconcelos, Nuno; Gopalacharyulu, Peddinti; Adrover, Anna; Jové Font, Mariona; Pamplona Gras, Reinald; Berenguer-Llergo, Antonio; Gordaliza, Isabel; Calvo, Enrique; Cabré, Noemí; Castro, Rui; Kuzmanic, Antonija; Boutant, Marie; Sala, David; Hyotylainen, Tuulia; Oresic, Matej; Fort, Joana; Errasti-Murugarren, Ekaitz; Orozco, Modesto; Joven, Jorge; Cantó, Carles; Palacin, Manuel; Fernández-Veledo, Sonia; Vendrell, Joan; Zorzano, Antonio (Elsevier, 2019-05-02)
      Non-alcoholic fatty liver is the most common liver disease worldwide. Here, we show that the mitochondrial protein mitofusin 2 (Mfn2) protects against liver disease. Reduced Mfn2 expression was detected in liver biopsies ...
    • Depletion of oxidative and endoplasmic reticulum stress regulators in Pick disease 

      Ilieva, Ekaterina V.; Naudí i Farré, Alba; Kichev, Anton Vladimirov; Ferrer, Isidre; Pamplona Gras, Reinald; Portero Otín, Manuel (Elsevier, 2010)
      Both oxidative and endoplasmic reticulum (ER) stress is associated with multiple neurodegenerative, age-related diseases. The rare disorder Pick disease (PiD) shares some pathological hallmarks of other neurodegenerative ...
    • Depression and Apathy After Transient Ischemic Attack or Minor Stroke: Prevalence, Evolution and Predictors 

      Carnes Vendrell, Anna; Deus Yela, Juan; Molina Seguin, Jessica; Pifarré Paredero, Josep; Purroy Garcia, Francisco (Nature Research, 2019)
      Few previous studies have focused on affective impairment after transient ischemic attack (TIA) and/or minor stroke. The aim was to establish the prevalence, evolution and predictors of post-stroke depression (PSD) and ...
    • Dermatofibrosarcoma protuberans sobre cicatriz de apendicectomía 

      Veà Jódar, Àlvar; Aguayo Ortiz, Rafael; Soria, Xavier; Sanmartín Novell, Verònica; Casanova i Seuma, Josep M. (Josep Manel) (Elsevier, 2015)
      El dermatofibrosarcoma protuberans (DFSP) es un tumor cutáneo relativamente raro, con una incidencia aproximada de 4 casos por cada millón de habitantes y año1,2. Ahora bien, es el sarcoma cutáneo más frecuente, ...
    • Dermatological Manifestations in the Intensive Care Unit: A Practical Approach 

      Badia Castello, Mariona; Casanova i Seuma, Josep M. (Josep Manel); Servià Goixart, Lluís; Montserrat, Neus; Codina, Jordi; Trujillano Cabello, Javier (Hindawi, 2020-09-26)
      Dermatological problems are not usually related to intensive medicine because they are considered to have a low impact on the evolution of critical patients. Despite this, dermatological manifestations (DMs) are relatively ...
    • Descriptive study of association between quality of care and empathy and burnout in primary care 

      Yuguero Torres, Oriol; Marsal Mora, Josep Ramon; Buti, Miquel; Esquerda i Aresté, Montse; Soler González, Jorge (BioMed Central, 2017)
      The doctor-patient relationship is a crucial aspect of primary-care practice Research on associations between quality of care provision and burnout and empathy in a primary care setting could improve this relationship.
    • Design and Validation of a Computer Application for Diagnosis of Shoulder Locomotor System Pathology 

      Bigordà Sagué, Albert; Trujillano Cabello, Javier; Ariza Carrió, Gemma; Campoy Guerrero, Carme (Korean Society of Medical Informatics, 2019)
      Objectives: To design and validate a computer application for the diagnosis of shoulder locomotor system pathology. Meth-ods: The first phase involved the construction of the application using the Delphi method. In the ...
    • Design, construction, and implementation of an online platform for patients with type 1 diabetes: EncoDiab 

      Alvarado-Martel, Dàcil; Cañas Ortiz, Francesca; Velasco, Rebeca; Alcubierre Calvo, Núria; López-Ríos, Laura; Rius, Ferran; Nóvoa, Francisco Javier; Carrillo, Armando; Hernández García, Marta; Wägner, Ana María; Mauricio Puente, Dídac (Dove Medical Press, 2015)
      Purpose: The purpose of this study was to develop, build, and implement a virtual platform equipped with practical tools, relevant contents, and communication rooms, with the aim of facilitating patients’ self-management ...
    • Design, optimization and validation of genes commonly used in expression studies on DMH/AOM rat colon carcinogenesis model 

      Bars-Cortina, David; Riera-Escamilla, Antoni; Gou, Gemma; Piñol Felis, Carme; Motilva Casado, Mª José (PeerJ, 2019-01-29)
      Colorectal cancer (CRC), also known as colon cancer, is the third most common form of cancer worldwide in men and the second in women and is characterized by several genetic alterations, among them the expression of several ...
    • Detection of Severe Obstructive Sleep Apnea through voice analysis 

      Solé-Casals, Jordi; Munteanu, Cristian; Capdevila Martín, Oriol; Barbé Illa, Ferran; Durán-Cantolla, Joaquín; Queipo, Carlos; Amilibia, Jose (Elsevier, 2014)
      This paper deals with the potential and limitations of using voice and speech processing to detect Obstructive Sleep Apnea (OSA). An extensive body of voice features has been extracted from patients who present various ...
    • Determinants of sensitivity to radiotherapy in endometrial cancer 

      Sorolla Bardají, Maria Alba; Parisi Capdevila, Eva; Sorolla Bardají, Anabel (MDPI, 2020)
      Radiotherapy is one of the cornerstone treatments for endometrial cancer and has successfully diminished the risk of local recurrences after surgery. However, a considerable percentage of patients suffers tumor relapse due ...
    • Development and evolution of the pallium 

      Medina Hernández, Loreta Mª; Abellán Ródenas, Antonio (Elsevier, 2009)
      The neocortex is the most representative and elaborated structure of the mammalian brain and is related to the achievement of complex cognitive capabilities, which are disturbed following malformation or lesion. Searching ...
    • Development of a sequential workflow based on LC-PRM for the verification of endometrial cancer protein biomarkers in uterine aspirate samples 

      Martínez García, Elena; Lesur, Antoine; Devis, Laura; Rosa Campos, Alexandre; Cabrera, Silvia; Oostrum, Jan van; Matias-Guiu, Xavier; Gil-Moreno, Antonio; Reventós, Jaume; Colás, Eva; Domon, Bruno (Impact Journals, 2016)
      About 30% of endometrial cancer (EC) patients are diagnosed at an advanced stage of the disease, which is associated with a drastic decrease in the 5-year survival rate. The identification of biomarkers in uterine aspirate ...
    • Development of neurons and fibers containing calcium binding proteins in the pallial amygdala of mouse, with special emphasis on those of the basolateral amygdalar complex 

      Legaz, Isabel; Olmos, Luis; Real, M. Ángeles; Guirado, Salvador; Dávila, José Carlos; Medina Hernández, Loreta Mª (Wiley, 2005)
      We studied the development of neurons and fibers containing calbindin, calretinin, and parvalbumin in the mouse pallial amygdala, with special emphasis on those of the basolateral amygdalar complex. Numerous calbindin-im ...
    • Developmental and Tissue-Specific Involvement of Peroxisome Proliferator-Activated Receptor-α in the Control of Mouse Uncoupling Protein-3 Gene Expression 

      Pedraza González, Neus; Rosell, Meritxell; Villarroya, Joan; Iglesias, Roser; Gonzalez, Frank J.; Solanes, Gemma; Villarroya, Francesc (Endocrine Society, 2006)
      Uncoupling protein-3 (UCP3) is a member of the mitochondrial carrier family expressed preferentially in skeletal muscle and heart. It appears to be involved in metabolic handling of fatty acids in a way that minimizes ...
    • Developmental silencing and independency from E2F of apoptotic gene expression in postmitotic tissues 

      Zhang, Jisheng; Bahi i Pla, Núria; Zubiaga, Ana M.; Comella i Carnicé, Joan Xavier; Llovera i Tomàs, Marta; Sanchis, Daniel (Wiley, 2007)
      The involvement of caspases in postmitotic cell death is controversial. Here we report that adult brain and heart are devoid of many key pro-apoptotic proteins due to a progressive postnatal silencing event involving a ...