Baseline residual kidney function and its ensuing rate of decline interact to predict mortality of peritoneal dialysis patients

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2016
Author
Pérez Fontán, Miguel
Remón Rodríguez, César
Cunha Naveira, Marta da
Borràs, Mercè
Rodríguez Suárez, Carmen
Quirós Ganga, Pedro
Sánchez Alvarez, Emilio
Rodríguez Carmona, Ana
Suggested citation
Pérez Fontán, Miguel; Remón Rodríguez, César; Cunha Naveira, Marta da; Borràs, Mercè; Rodríguez Suárez, Carmen; Quirós Ganga, Pedro; ... Rodríguez Carmona, Ana. (2016) . Baseline residual kidney function and its ensuing rate of decline interact to predict mortality of peritoneal dialysis patients. Plos One, 2016, vol. 11, núm. 7, p. 1-11. https://doi.org/10.1371/journal.pone.0158696.
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Abstract
Background Baseline residual kidney function (RKF) and its rate of decline during follow-up are purported to be reliable outcome predictors of patients undergoing Peritoneal Dialysis (PD). The independent contribution of each of these factors has not been elucidated. Method We report a multicenter, longitudinal study of 493 patients incident on PD and satisfying two conditions: a glomerular filtration rate (GFR) 1 mL/minute and a daily diuresis 300 mL. The main variables were the GFR (mean of urea and creatinine clearances) at PD inception and the GFR rate of decline during follow-up. The main outcome variable was patient mortality. The secondary outcome variables were: PD technique failure and risk of peritoneal infection. The statistical analysis was based on a multivariate approach, placing an emphasis on the interactions between the two main study variables.
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http://hdl.handle.net/10459.1/59975
DOI
https://doi.org/10.1371/journal.pone.0158696
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Plos One, 2016, vol. 11, núm. 7, p. 1-11
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cc-by (c) Pérez Fontán et al., 2016
Except where otherwise noted, this item's license is described as cc-by (c) Pérez Fontán et al., 2016