Iodine deficiency is higher in morbid obesity in comparison with late after bariatric surgery and non-obese women
Fort, José Manuel
MetadataShow full item record
Background Iodine deficiency and obesity are worldwideoccurring health problems. Our purpose was to investigate the relationship between morbid obesity and iodine status, including subjects who lost weight after bariatric surgery. Methods Ninety morbidly obese women, 90 women with at least 18 months follow-up after bariatric surgery, and 45 healthy non-obese women were recruited. Urinary iodine concentration (UIC) was measured in a spot urinary sample and expressed as the iodine-to-creatinine ratio. Results Obese women showed a significantly lower UIC in comparison with non-obese women (96.6 (25.8–267.3) vs. 173.3 (47.0–493.6) μg/g; p<0.001), with a lesser proportion of subjects with adequate iodine status (46.6 vs. 83.3 %, p<0.001). The mean UIC significantly increased among women who underwent bariatric surgery before the collection of the urinary sample (96.6 (25.8–267.3) vs. 131.9 (62.9– 496.4) μg/g; p<0.001). No difference in UIC was detected between laparoscopic Roux-en-Y gastric bypass and laparoscopic sleeve gastrectomy. Univariate analysis showed that UIC negatively correlated with body mass index (BMI) (r=−0.278, p<0.001) and positively with age (r=0.206, p=0.002). Finally, multiple linear regression analyses showed that BMI was independently associated with UIC (beta=−0.312, p<0.001; R2=0.166). Conclusion Obesity is an independent risk factor to iodine deficiency, almost in women.Whether more obese population needs to be considered as a vulnerable group and whether bariatric surgery can reverse iodine deficiency still remain to be elucidated.
Is part ofObesity Surgery, 2015, vol. 25, núm. 1, p. 85–89
European research projects
Showing items related by title, author, creator and subject.
Surgically induced weight loss by gastric bypass improves non alcoholic fatty liver disease in morbid obese patients Vargas, Víctor; Allende, Helena; Lecube Torelló, Albert; Salcedo, Maria Teresa; Baena-Fustegueras, Juan A; Fort, José Manuel; Rivero, Joaquín; Ferrer, Roser; Catalán, Roberto; Pardina, Eva; Ramón y Cajal, Santiago; Guardia, Jaime; Peinado-Onsurbe, Julia (Baishideng Publishing Group, 2012)AIM: To evaluate the effects of surgical weight loss (Roux-en-Y gastric bypass with a modified Fobi-Capella technique) on non alcoholic fatty liver disease in obese patients. METHODS: A group of 26 morbidly obese ...
Diabetic and dyslipidaemic morbidly obese exhibit more liver alterations compared with healthy morbidly obese Pardina, Eva; Ferrer, Roser; Rossell, Joana; Baena-Fustegueras, Juan A; Lecube Torelló, Albert; Fort, José Manuel; Caubet, Enric; González, Óscar; Vilallonga, Ramón; Vargas, Víctor; Balibrea, José María; Peinado-Onsurbe, Julia (Elsevier, 2016)Background & aims: To study the origin of fat excess in the livers of morbidly obese (MO) individuals, we analysed lipids and lipases in both plasma and liver and genes involved in lipid transport, or related with, in that ...
The role of morbid obesity in the promotion of metabolic disruptions and non-alcoholic steatohepatitis by Helicobacter Pylori Lecube Torelló, Albert; Valladares, Silvia; López Cano, Carolina; Gutiérrez Carrasquilla, Liliana; Ciudin, Andreea; Fort, José Manuel; Reñé Espinet, Josep Maria; Matias-Guiu, Xavier; Torres, Inés de; Bueno Díez, Marta; Pallares, Judit; Baena-Fustegueras, Juan A (Public Library of Science, 2016)Helicobacter pylory (HP) infection has been associated to an increased rate of type 2 diabetes (T2D) and liver disease through its effect on insulin resistance and systemic inflammation. However, results are inconstant ...