Show simple item record

dc.contributor.authorMedina Hernández, Loreta Mª
dc.contributor.authorBrox, Aurora
dc.contributor.authorLegaz, Isabel
dc.contributor.authorGarcía López, Margarita
dc.contributor.authorPuelles, Luis
dc.date.accessioned2017-01-20T09:46:12Z
dc.date.issued2005
dc.identifier.issn0361-9230
dc.identifier.urihttp://hdl.handle.net/10459.1/59052
dc.description.abstractIn this study, we review data on the existence of comparable divisions and subdivisions in the telencephalon of different groups of tetrapods based on expression of some developmental regulatory genes, having a particular focus in the comparison of the anuran amphibian Xenopus and the mouse. The available data on Xenopus, mouse, chick and turtle indicate that apparently all tetrapod groups possess the same molecularly distinct divisions and subdivisions in the telencephalon. This basic organization was likely present in the telencephalon of stem tetrapods. Each division/subdivision is characterized by expression of a unique combination of developmental regulatory genes, and appears to represent a self-regulated and topologically constant histogenetic brain compartment that gives rise to specific groups of cells. This interpretation has an important consequence for searching homologies, since a basic condition for cell groups in different vertebrates to be considered homologous is that they originate in the same compartment. However, evolution may allow individual cell groups derived from comparable (field homologous) subdivisions to be either similar or dissimilar across the vertebrate groups, giving rise to several possible scenarios of evolution, which include both the evolutionary conservation of similar (homologous) cells or the production of novel cell groups. Finally, available data in the lamprey, a jawless fish, suggest that not all telencephalic subdivisions were present at the origin of vertebrates, raising important questions about their evolution.ca_ES
dc.description.sponsorshipThis work was supported by the Spanish Ministry of Science and Technology (CYCIT-FEDER; Grants BFI2000- 1359-C02-02 and BFI2003-06453-C02-02 to L.M.; fellowship FP2000-5943 to I.L.), the Spanish Ministry of Health- Institute Carlos III (Grant FIS-FEDER 01/0057-02 to L.M. and Red CIEN-Nodo 318) and S´eneca Foundation (Grant PB/50/FS/02 to L.M.).ca_ES
dc.language.isoengca_ES
dc.publisherElsevierca_ES
dc.relationMICYT/PN2000-2003/BFI2000-1359-C02-02
dc.relationMICYT/PN2000-2003/BFI2003-06453-C02-02
dc.relation.isformatofReproducció del document publicat a https://doi.org/10.1016/j.brainresbull.2005.02.003ca_ES
dc.relation.ispartofBrain Research Bulletin, 2005, vol. 66, núm. 4–6, p. 297–302ca_ES
dc.rights(c) Elsevier Inc, 2005ca_ES
dc.subjectVentral palliumca_ES
dc.subjectLateral palliumca_ES
dc.subjectClaustrumca_ES
dc.subjectPallial amygdalaca_ES
dc.subjectDVRca_ES
dc.titleExpression patterns of developmental regulatory genes show comparable divisions in the telencephalon of Xenopus and mouse: insights into the evolution of the forebrainca_ES
dc.typearticleca_ES
dc.identifier.idgrec011372
dc.type.versionpublishedVersionca_ES
dc.rights.accessRightsinfo:eu-repo/semantics/restrictedAccessca_ES
dc.identifier.doihttps://doi.org/10.1016/j.brainresbull.2005.02.003
dc.date.embargoEndDate2025-01-01


Files in this item

Thumbnail

This item appears in the following Collection(s)

Show simple item record