Epigenetic profiling to classify cancer of unknown primary: a multicentre, retrospective analysis

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2016
Author
Moran, Sebastian
Martínez Cardús, Anna
Sayols, Sergi
Musulén, Eva
Balañá, Carme
Estival Gonzalez, Anna
Moutinho, Cátia
Heyn, Holger
Diaz Lagares, Angel
Castro de Moura, Manuel
Stella, Giulia M.
Comoglio, Paolo M.
Ruiz Miró, Maria
Pazo Cid, Roberto
Antón, Antonio
Lopez Lopez, Rafael
Soler, Gemma
Longo, Federico
Guerra, Isabel
Fernandez, Sara
Assenov, Yassen
Plass, Christoph
Morales, Rafael
Carles, Joan
Bowtell, David
Mileshkin, Linda
Sia, Daniela
Tothill, Richard
Tabernero, Josep
Llovet, Josep M.
Esteller, Manel
Matias-Guiu, Xavier
Suggested citation
Moran, Sebastian; Martínez Cardús, Anna; Sayols, Sergi; Musulén, Eva; Balañá, Carme; Estival Gonzalez, Anna; ... Matias-Guiu, Xavier. (2016) . Epigenetic profiling to classify cancer of unknown primary: a multicentre, retrospective analysis. The Lancet Oncology, 2016, vol. 17, núm. 10, p. 1286-1395. https://doi.org/10.1016/S1470-2045(16)30297-2.
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Abstract
Cancer of unknown primary ranks in the top ten cancer presentations and has an extremely poor prognosis. Identification of the primary tumour and development of a tailored site-specific therapy could improve the survival of these patients. We examined the feasability of using DNA methylation profiles to determine the occult original cancer in cases of cancer of unknown primary.
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http://hdl.handle.net/10459.1/58773
DOI
https://doi.org/10.1016/S1470-2045(16)30297-2
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The Lancet Oncology, 2016, vol. 17, núm. 10, p. 1286-1395
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