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dc.contributor.authorMonné Esquerda, Josep
dc.contributor.authorDíez, Yolanda
dc.contributor.authorPuy Llorens, Jaume
dc.contributor.authorGalceran i Nogués, Josep
dc.contributor.authorNelson, Andrew
dc.date.accessioned2016-11-23T11:44:51Z
dc.date.issued2007
dc.identifier.issn0743-7463
dc.identifier.urihttp://hdl.handle.net/10459.1/58630
dc.description.abstractThe exponentially decaying permeability model interprets the chronoamperometric currents arising from Tl+ reduction at a Hg electrode covered with a phospholipid monolayer (DOPC) containing gramicidin monomer by combining three processes: (i) the diffusion of an ion to a membrane surface with an array of channels, (ii) the conformational dynamics of the individual channels, and (iii) the passage of the ion through the channels. The introduction of a variable permeability allows us to uncouple the diffusion from the heterogeneous processes, given that the concentration of a species at the active surface can be obtained by semi-integration of the currents. Consideration of a reverse step for the dehydration process at the mouth of the channel allows the analysis of potential steps away from diffusionlimited conditions where a Nernstian-like behavior of the relevant parameter is observed. The model has been successfully applied to data with all trans retinol or benzo-R-pyrene as additive to the phospholipid monolayer and to monolayers without any additive at all.ca_ES
dc.description.sponsorshipThe authors gratefully acknowledge support of this research by BBMO #005199 FP6-2003-LifeSciHealth-Specific Action Support, by the Spanish Ministry of Education and Science (Projects CTQ2006-14385 and CTM2006- 13583), and from the “Comissionat d’Universitats i Recerca de la Generalitat de Catalunya”.ca_ES
dc.language.isoengca_ES
dc.publisherAmerican Chemical Societyca_ES
dc.relationMIECI/PN2004-2007/CTQ2006-14385ca_ES
dc.relationMIECI/PN2004-2007/CTM2006-13583ca_ES
dc.relation.isformatofReproducció del document publicat a https://doi.org/10.1021/la701447gca_ES
dc.relation.ispartofLangmuir, 2007, vol. 23, núm. 21, p. 10581-10588ca_ES
dc.rights(c) American Chemical Society, 2007ca_ES
dc.titleInterpreting ion fluxes to channel arrays in monolayersca_ES
dc.typearticleca_ES
dc.identifier.idgrec011568
dc.type.versionpublishedVersionca_ES
dc.rights.accessRightsinfo:eu-repo/semantics/restrictedAccessca_ES
dc.identifier.doihttps://doi.org/10.1021/la701447g
dc.date.embargoEndDate10000-01-01


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