| dc.contributor.author | Monné Esquerda, Josep | |
| dc.contributor.author | Díez, Yolanda | |
| dc.contributor.author | Puy Llorens, Jaume | |
| dc.contributor.author | Galceran i Nogués, Josep | |
| dc.contributor.author | Nelson, Andrew | |
| dc.date.accessioned | 2016-11-23T11:44:51Z | |
| dc.date.issued | 2007 | |
| dc.identifier.issn | 0743-7463 | |
| dc.identifier.uri | http://hdl.handle.net/10459.1/58630 | |
| dc.description.abstract | The exponentially decaying permeability model interprets the chronoamperometric currents arising from Tl+ reduction
at a Hg electrode covered with a phospholipid monolayer (DOPC) containing gramicidin monomer by combining three
processes: (i) the diffusion of an ion to a membrane surface with an array of channels, (ii) the conformational dynamics
of the individual channels, and (iii) the passage of the ion through the channels. The introduction of a variable
permeability allows us to uncouple the diffusion from the heterogeneous processes, given that the concentration of
a species at the active surface can be obtained by semi-integration of the currents. Consideration of a reverse step
for the dehydration process at the mouth of the channel allows the analysis of potential steps away from diffusionlimited
conditions where a Nernstian-like behavior of the relevant parameter is observed. The model has been successfully
applied to data with all trans retinol or benzo-R-pyrene as additive to the phospholipid monolayer and to monolayers
without any additive at all. | ca_ES |
| dc.description.sponsorship | The authors gratefully acknowledge support of this research by BBMO #005199 FP6-2003-LifeSciHealth-Specific Action Support, by the Spanish Ministry of Education and Science (Projects CTQ2006-14385 and CTM2006- 13583), and from the “Comissionat d’Universitats i Recerca de la Generalitat de Catalunya”. | ca_ES |
| dc.language.iso | eng | ca_ES |
| dc.publisher | American Chemical Society | ca_ES |
| dc.relation | MIECI/PN2004-2007/CTQ2006-14385 | ca_ES |
| dc.relation | MIECI/PN2004-2007/CTM2006-13583 | ca_ES |
| dc.relation.isformatof | Reproducció del document publicat a https://doi.org/10.1021/la701447g | ca_ES |
| dc.relation.ispartof | Langmuir, 2007, vol. 23, núm. 21, p. 10581-10588 | ca_ES |
| dc.rights | (c) American Chemical Society, 2007 | ca_ES |
| dc.title | Interpreting ion fluxes to channel arrays in monolayers | ca_ES |
| dc.type | article | ca_ES |
| dc.identifier.idgrec | 011568 | |
| dc.type.version | publishedVersion | ca_ES |
| dc.rights.accessRights | info:eu-repo/semantics/restrictedAccess | ca_ES |
| dc.identifier.doi | https://doi.org/10.1021/la701447g | |
| dc.date.embargoEndDate | 2025-01-01 | |
