Interpreting ion fluxes to channel arrays in monolayers
Monné Esquerda, Josep
MetadataShow full item record
The exponentially decaying permeability model interprets the chronoamperometric currents arising from Tl+ reduction at a Hg electrode covered with a phospholipid monolayer (DOPC) containing gramicidin monomer by combining three processes: (i) the diffusion of an ion to a membrane surface with an array of channels, (ii) the conformational dynamics of the individual channels, and (iii) the passage of the ion through the channels. The introduction of a variable permeability allows us to uncouple the diffusion from the heterogeneous processes, given that the concentration of a species at the active surface can be obtained by semi-integration of the currents. Consideration of a reverse step for the dehydration process at the mouth of the channel allows the analysis of potential steps away from diffusionlimited conditions where a Nernstian-like behavior of the relevant parameter is observed. The model has been successfully applied to data with all trans retinol or benzo-R-pyrene as additive to the phospholipid monolayer and to monolayers without any additive at all.
Is part ofLangmuir, 2007, vol. 23, núm. 21, p. 10581-10588
European research projects
Showing items related by title, author, creator and subject.
Galceran i Nogués, Josep; Puy Llorens, Jaume (CSIRO Publishing, 2015)Gaining insight into the physicochemical processes integrated in a DGT (diffusion gradients in thin films) measurement and combining them in a model can assist in retrieving fundamental information, both qualitative and ...
Voltammetric currents for any ligand-to-metal concentration ratio in fully labile metal-macromolecular complexation. Easy computations, analytical properties of the currents and graphical method to estimate the stability constant Galceran i Nogués, Josep; Cecilia Averós, Joan; Salvador, José; Monné Esquerda, Josep; Torrent, Marià; Companys Ferran, Encarnació; Puy Llorens, Jaume; Garcés, Josep Lluís; Mas i Pujadas, Francesc (Elsevier, 1999)In order to enable a wider use of voltammetric methods in speciation analysis, it is convenient not to be restricted by ligand excess conditions. This work assumes labile ideal complexation of a metal ion by a ligand, ...
Transient biouptake flux and accumulation by microorganisms: the case of two types of sites with Langmuir adsorption Galceran i Nogués, Josep; Monné Esquerda, Josep; Puy Llorens, Jaume; Leeuwen, Herman P. van (Elsevier, 2006)The uptake of a chemical species by an aquatic microorganism is modelled considering two kinds of sites where Langmuirian adsorption is followed by first order internalisation kinetics. Simpler models, such as only one ...