Lipidomic and metabolomic analyses reveal potential plasma biomarkers of early atheromatous plaque formation in hamsters
Issue date
2013Author
Ramírez-Núñez, Omar
Arola i Ferrer, Lluís
Caimari, Antoni
Bas, Josep M. del
Crescenti, Anna
Suggested citation
Jové Font, Mariona;
Ayala Jové, Ma. Victoria (Maria Victoria);
Ramírez-Núñez, Omar;
Serrano Casasola, José Carlos Enrique;
Cassanyé, Anna;
Arola i Ferrer, Lluís;
...
Portero Otín, Manuel.
(2013)
.
Lipidomic and metabolomic analyses reveal potential plasma biomarkers of early atheromatous plaque formation in hamsters.
Cardiovascular Research, 2013, vol. 97, p. 642-652.
https://doi.org/10.1093/cvr/cvs368.
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Aims Atherosclerosis is the main pathological process contributing to cardiovascular disease, with diet being the most important factor involved. Although the lipidome of atheromatous plaque has been studied previously, the use of comparative lipidomics and metabolomics in plasma in early atherogenesis could lead to the discovery of plasma biomarkers that allow not only disease prediction but also measurement of disease progression.