Lipidomic and metabolomic analyses reveal potential plasma biomarkers of early atheromatous plaque formation in hamsters

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2013
Author
Jové Font, Mariona
Ayala Jové, Ma. Victoria (Maria Victoria)
Ramírez-Núñez, Omar
Serrano Casasola, José Carlos Enrique
Cassanyé, Anna
Arola i Ferrer, Lluís
Caimari, Antoni
Bas, Josep M. del
Crescenti, Anna
Pamplona Gras, Reinald
Portero Otín, Manuel
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Abstract
Aims Atherosclerosis is the main pathological process contributing to cardiovascular disease, with diet being the most important factor involved. Although the lipidome of atheromatous plaque has been studied previously, the use of comparative lipidomics and metabolomics in plasma in early atherogenesis
could lead to the discovery of plasma biomarkers that allow not only disease prediction but also measurement of disease progression.
URI
http://hdl.handle.net/10459.1/58517
DOI
https://doi.org/10.1093/cvr/cvs368
Is part of
Cardiovascular Research, 2013, vol. 97, p. 642-652
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