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dc.contributor.authorTantra, Ratna
dc.contributor.authorBouwmeester, Hans
dc.contributor.authorBolea, Eduardo
dc.contributor.authorRey Castro, Carlos
dc.contributor.authorDavid, Calin
dc.contributor.authorDogné, Jean Michel
dc.contributor.authorJarman, John
dc.contributor.authorLaborda, Francisco
dc.contributor.authorLaloy, Julie
dc.contributor.authorRobinson, Kenneth N.
dc.contributor.authorUndas, Anna K.
dc.contributor.authorVan der Zande, Meike
dc.date.accessioned2016-11-10T10:38:26Z
dc.date.issued2016
dc.identifier.issn1743-5390
dc.identifier.urihttp://hdl.handle.net/10459.1/58463
dc.description.abstractSolubility is an important physicochemical parameter in nanoregulation. If nanomaterial is completely soluble, then from a risk assessment point of view, its disposal can be treated much in the same way as “ordinary” chemicals, which will simplify testing and characterisation regimes. This review assesses potential techniques for the measurement of nanomaterial solubility and evaluates the performance against a set of analytical criteria (based on satisfying the requirements as governed by the cosmetic regulation as well as the need to quantify the concentration of free (hydrated) ions). Our findings show that no universal method exists. A complementary approach is thus recommended, to comprise an atomic spectrometry-based method in conjunction with an electrochemical (or colorimetric) method. This article shows that although some techniques are more commonly used than others, a huge research gap remains, related with the need to ensure data reliability.ca_ES
dc.description.sponsorshipWe acknowledge support from European Union Seventh Framework Programme (FP7-NMP.2012.1.3-3) under grant agreement no. 310584 (NANoREG). This work was supported by the Service Public de Wallonie (SPW) – Direction ge´ne´rale ope´rationnelle – Economie, Emploi et Recherche (DGO6), De´partement des Programmes de Recherche (NANoREG, SPW/UNamur research convention N 1317938).ca_ES
dc.language.isoengca_ES
dc.publisherTaylor & Francisca_ES
dc.relation.isformatofReproducció del document publicat a https://doi.org/10.3109/17435390.2015.1038661ca_ES
dc.relation.ispartofNanotoxicology, 2016, vol. 10, núm. 2, p. 173-184ca_ES
dc.rights(c) Informa UK, 2015ca_ES
dc.subjectNanomaterialsca_ES
dc.subjectRegulationca_ES
dc.subjectSolubilityca_ES
dc.titleSuitability of analytical methods to measure solubility for the purpose of nanoregulationca_ES
dc.typearticleca_ES
dc.identifier.idgrec025154
dc.type.versionpublishedVersionca_ES
dc.rights.accessRightsinfo:eu-repo/semantics/restrictedAccessca_ES
dc.identifier.doihttps://doi.org/10.3109/17435390.2015.1038661
dc.relation.projectIDinfo:eu-repo/grantAgreement/EC/FP7/310584
dc.date.embargoEndDate10000-01-01


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