Universitat de Lleida
    • English
    • català
    • español
  • English 
    • English
    • català
    • español
  • Login
Repositori Obert UdL
View Item 
  •   Home
  • Recerca
  • Medicina Experimental
  • Articles publicats (Medicina Experimental)
  • View Item
  •   Home
  • Recerca
  • Medicina Experimental
  • Articles publicats (Medicina Experimental)
  • View Item
JavaScript is disabled for your browser. Some features of this site may not work without it.

Genomic response programs of Candida albicans following protoplasting and regeneration

Thumbnail
View/Open
024767.pdf (237.3Kb)
Sol·licita una còpia
Issue date
2005-12-16
Author
Castillo, Luis
Martínez, Ana Isabel
Garcera, Ana
García-Martínez, José
Ruiz-Herrera, José
Valentín, Eulogio
Sentandreu, Rafael
Suggested citation
Castillo, Luis; Martínez, Ana Isabel; Garcera, Ana; García-Martínez, José; Ruiz-Herrera, José; Valentín, Eulogio; Sentandreu, Rafael; . (2005) . Genomic response programs of Candida albicans following protoplasting and regeneration. Fungal Genetics and Biology, 2005, num. 43, p. 124-134. https://doi.org/10.1016/j.fgb.2005.12.002.
Impact


Web of Science logo    citations in Web of Science

Scopus logo    citations in Scopus

Google Scholar logo  Google Scholar
Share
Export to Mendeley
Metadata
Show full item record
Abstract
Transcription proWling of Candida albicans cells responding to the elimination of the wall (protoplasts) and posterior regeneration was explored. DNA microarrays were used to measure changes in the expression of 6039 genes, and the upregulated genes during regeneration at 28 °C were assigned to fourteen categories. A total of 407 genes were upregulated during the process, of which 144 reached a maximum after 1 h. MKC1, a gene encoding a member of the regulatory pathway involved in cell wall integrity was overexpressed. Time-dependent expression divided the genes into 40 clusters. Clusters 1-19 were highly expressed initially (time 0) and downregulated following incubation, whereas transcription of the genes grouped into clusters 20-40 showed the opposite behaviour. These results suggest that the Wrst clusters group genes permitting the cell adaptation to a sub-optimal environment due to removal of the wall, whereas the second group represents genes required for protoplasts regeneration after shifted to optimal conditions from 4 to 28 °C.
URI
http://hdl.handle.net/10459.1/57914
DOI
https://doi.org/10.1016/j.fgb.2005.12.002
Is part of
Fungal Genetics and Biology, 2005, num. 43, p. 124-134
European research projects
Collections
  • Articles publicats (Medicina Experimental) [323]

Contact Us | Send Feedback | Legal Notice
© 2022 BiD. Universitat de Lleida
Metadata subjected to 
 

 

Browse

All of the repositoryCommunities & CollectionsBy Issue DateAuthorsTitlesSubjectsThis CollectionBy Issue DateAuthorsTitlesSubjects

Statistics

View Usage Statistics

D'interès

Política institucional d'accés obertDiposita les teves publicacionsDiposita dades de recercaSuport a la recerca

Contact Us | Send Feedback | Legal Notice
© 2022 BiD. Universitat de Lleida
Metadata subjected to