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dc.contributor.authorSánchez de la Torre, Alicia
dc.contributor.authorAbad, Jorge
dc.contributor.authorDurán-Cantolla, Joaquín
dc.contributor.authorMediano, Olga
dc.contributor.authorCabriada, Valentín
dc.contributor.authorMasdeu, María José
dc.contributor.authorTerán, Joaquin
dc.contributor.authorMasa, Juan F.
dc.contributor.authorPeña, Mónica de la
dc.contributor.authorAldomá, Albina
dc.contributor.authorWorner, Fernando
dc.contributor.authorValls Marsal, Joan
dc.contributor.authorBarbé Illa, Ferran
dc.contributor.authorSánchez de la Torre, Manuel
dc.date.accessioned2016-09-01T10:39:01Z
dc.date.available2016-09-01T10:39:01Z
dc.date.issued2016
dc.identifier.issn1932-6203
dc.identifier.urihttp://hdl.handle.net/10459.1/57761
dc.description.abstractBackground: The cardiovascular consequences of obstructive sleep apnoea (OSA) differ by sex. We hypothesized that sex influences the severity of acute coronary syndrome (ACS) in patients with OSA. OSA was defined as an apnoea–hypopnoea index (AHI)>15 events·h-1. We evaluated the severity of ACS according to the ejection fraction, Killip class, number of diseased vessels, number of stents implanted and plasma peak troponin level. Methods: We included 663 men (mean±SD, AHI 37±18 events·h-1) and 133 women (AHI 35±18 events·h-1) with OSA. Results: The men were younger than the women (59±11 versus 66±11 years, p<0.0001), exhibited a higher neck circumference (p<0.0001), and were more likely to be smokers and alcohol users than women (p<0.0001, p = 0.0005, respectively). Body mass index and percentage of hypertensive patients or diabetics were similar between sexes. We observed a slight tendency for a higher Killip classification in women, although it was not statistically significant (p = 0.055). For men, we observed that the number of diseased vessels and the number of stents implanted were higher (p = 0.02, p = 0.001, respectively), and a decrease in the ejection fraction (p = 0.002). Conclusions: This study shows that sex in OSA influences the severity of ACS. Men show a lower ejection fraction and an increased number of diseased vessels and number of stents implanted.ca_ES
dc.language.isoengca_ES
dc.publisherPublic Library of Scienceca_ES
dc.relation.isformatofReproducció del document publicat a https://doi.org/10.1371/journal.pone.0159207ca_ES
dc.relation.ispartofPLoS ONE, 2016, vol. 11, núm. 7, e0159207ca_ES
dc.rightscc-by, (c) Sánchez de la Torre et al., 2016ca_ES
dc.rights.urihttp://creativecommons.org/licenses/by/3.0/es/*
dc.subject.otherArtèries coronàries -- Malaltiesca_ES
dc.titleEffect of Patient Sex on the Severity of Coronary Artery Disease in Patients with Newly Diagnosis of Obstructive Sleep Apnoea Admitted by an Acute Coronary Syndromeca_ES
dc.typearticleca_ES
dc.identifier.idgrec025233
dc.type.versionpublishedVersionca_ES
dc.rights.accessRightsinfo:eu-repo/semantics/openAccessca_ES
dc.identifier.doihttps://doi.org/10.1371/journal.pone.0159207


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cc-by, (c) Sánchez de la Torre et al., 2016
Except where otherwise noted, this item's license is described as cc-by, (c) Sánchez de la Torre et al., 2016