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dc.contributor.authorBlanch, Jordi
dc.contributor.authorSala i Serra, Maria
dc.contributor.authorRomán Expósito, Marta
dc.contributor.authorEderra, M.
dc.contributor.authorSalas, Dolores
dc.contributor.authorZubizarreta, Raquel
dc.contributor.authorSánchez-Jacob, Mercedes
dc.contributor.authorRué i Monné, Montserrat
dc.contributor.authorCastells, Xavier
dc.date.accessioned2016-05-09T09:22:43Z
dc.date.issued2013
dc.identifier.issn0167-6806
dc.identifier.urihttp://hdl.handle.net/10459.1/56985
dc.description.abstractBackground There is little information on the individual risk of screen-detected cancer in women over successive participations. This study aimed to estimate the 10-year cumulative breast cancer detection risk (ductal carcinoma in situ and invasive carcinoma) in a populationbased breast cancer screening program according to distinct protocol strategies. A further aim was to determine which strategies maximized the cancer detection risk and how this risk was affected by the radiologic protocol variables. Methods Data were drawn from a retrospective cohort of women from nine population-based screening programs in Spain from 1990 to 2006. We used logistic regression with discrete intervals to estimate the cumulative detection risk at 10 years of follow-up according to radiologic variables and protocol strategies. Results In women starting screening at the age of 45–59 years, the cumulative risk of screen-detected cancer at 10 years ranged from 11.11 to 16.71 per 1,000 participants according to the protocol strategy. The cumulative detection risk for overall cancer and invasive cancer was the highest with strategies using digital mammography, double reading, and two projections (16.71 and 12.07 %, respectively). For ductal carcinoma in situ, cumulative detection risk was the highest with strategies using screen-film, double reading, and two projections (2.32 %). The risk was the lowest with strategies using screen-film mammography, single reading, and two projections. Conclusions This study found that at least eleven cancers are detected per 1,000 women screened in the first 10 years of follow-up. Enhanced knowledge of the variability in cumulative risk of screendetected cancer could improve protocol strategies.ca_ES
dc.language.isoengca_ES
dc.publisherSpringer Verlagca_ES
dc.relation.isformatofReproducció del document publicat a https://doi.org/10.1007/s10549-013-2458-5ca_ES
dc.relation.ispartofBreast Cancer Research and Treatment, 2013, vol. 138, núm. 3, p. 869-877ca_ES
dc.rights(c) Springer Verlag, 2013ca_ES
dc.subjectBreast cancerca_ES
dc.subjectScreeningca_ES
dc.subjectCumulative riskca_ES
dc.titleCumulative risk of cancer detection in breast cancer screening by protocol strategyca_ES
dc.typearticleca_ES
dc.identifier.idgrec019258
dc.type.versionpublishedVersionca_ES
dc.rights.accessRightsinfo:eu-repo/semantics/restrictedAccessca_ES
dc.identifier.doihttps://doi.org/10.1007/s10549-013-2458-5
dc.date.embargoEndDate2025-01-01


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