Biofortification of plants with altered antioxidant content and composition: genetic engineering strategies
Sanahuja Solsona, Georgina
Arjó Pont, Gemma
Berman Quintana, Judit
Zorrilla López, Uxue
Pérez Massot, Eduard
MetadataShow full item record
Antioxidants are protective molecules that neutralize reactive oxygen species and prevent oxidative damage to cellular components such as membranes, proteins and nucleic acids, therefore reducing the rate of cell death and hence the effects of ageing and ageing-related diseases. The fortification
of food with antioxidants represents an overlap between two diverse environments, namely fortification of staple foods with essential nutrients that happen to have antioxidant properties (e.g. vitamins C and E) and the fortification of luxury foods with healthpromoting but non-essential antioxidants such as flavonoids as part of the nutraceuticals/ functional foods industry. Although processed foods can be artificially fortified with vitamins, minerals and nutraceuticals, a more sustainable approach is to introduce the traits for such health-promoting compounds at source, an approach known as biofortification. Regardless of the target compound, the same challenges arise when considering the biofortification of plants with antioxidants, that is the need to modulate endogenous metabolic pathways to increase the production of specific antioxidants without affecting plant growth and development and without collateral effects on other metabolic pathways. These challenges become even more intricate as we move from the engineering of individual pathways to several pathways simultaneously. In this review, we consider the state of the art in antioxidant biofortification and discuss the challenges that remain to be overcome in the development of nutritionally complete and health-promoting functional foods.
Is part ofPlant Biotechnology Journal, 2013, vol. 11, p. 129-141
Showing items related by title, author, creator and subject.
The contribution of transgenic plants to better health through improved nutrition: opportunities and constraints Pérez Massot, Eduard; Banakar, Raviraj; Gómez Galera, Sonia; Zorrilla López, Uxue; Sanahuja Solsona, Georgina; Arjó Pont, Gemma; Miralpeix i Anglada, Bruna; Vamvaka, Evangelia; Farré Martinez, Gemma; Rivera Vélez, Sol Maiam; Dashevskaya, Svetlana; Berman Quintana, Judit; Sabalza Gallués, Maite; Yuan, Dawei; Bai, Chao; Bassie Rene, Ludovic; Twyman, Richard M.; Capell Capell, Teresa; Christou, Paul; Zhu, Changfu (Springer Verlag, 2013)Malnutrition is a prevalent and entrenched global socioeconomic challenge that reflects the combined impact of poverty, poor access to food, inefficient food distribution infrastructure, and an over-reliance on ...
Zorrilla López, Uxue; Masip Vilà, Gemma; Arjó Pont, Gemma; Bai, Chao; Banakar, Raviraj; Bassie Rene, Ludovic; Berman Quintana, Judit; Farré Martinez, Gemma; Miralpeix i Anglada, Bruna; Pérez Massot, Eduard; Sabalza Gallués, Maite; Sanahuja Solsona, Georgina; Vamvaka, Evangelia; Twyman, Richard M.; Christou, Paul; Zhu, Changfu; Capell Capell, Teresa (University of the Basque Country Press, 2013)Metabolic engineering in plants can be used to increase the abundance of specific valuable metabolites, but single-point interventions generally do not improve the yields of target metabolites unless that product is ...
Berman Quintana, Judit; Zhu, Changfu; Pérez Massot, Eduard; Arjó Pont, Gemma; Zorrilla López, Uxue; Masip Vilà, Gemma; Banakar, Raviraj; Sanahuja Solsona, Georgina; Farré Martinez, Gemma; Miralpeix i Anglada, Bruna; Bai, Chao; Vamvaka, Evangelia; Sabalza Gallués, Maite; Twyman, Richard M.; Bassie Rene, Ludovic; Capell Capell, Teresa; Christou, Paul (Springer Verlag, 2013)Genetically engineered (GE) crops can be used as part of a combined strategy to address food insecurity, which is defined as a lack of sustainable access to safe and nutritious food. In this article, we discuss the ...