Carotenoid-enriched Transgenid Corn in Poultry Nutrition
Díaz Gómez, Joana
Moreno Martínez, José Antonio
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Vitamin A deficiency (VAD) is one of the most important micronutrient deficiencies globally. It is prevalent throughout the world, but it is particularly severe in Africa and South-East Asia. The main underlying cause of VAD is a chronic insufficient vitamin A intake in the diet, which can lead to disorders such as xerophthalmia, anaemia and weakened resistance to infection. It has been estimated that VAD affects up to one third of the world’s pre-school-age children and up to 15% of pregnant women 1 .Vitamin fortification programs are unsustainable due to poor governance, inefficient food distribution networks, and the prevalence of subsistence agriculture in rural populations 2 . Biofortification of staple crops with organic nutrients is a cost-effective and sustainable approach as exemplified by Golden Rice 3 with high-levels of β-carotene, and Multivitamin Corn 4 accumulating high levels of β-carotene, zeaxanthin, lutein, lycopene, ascorbic acid, and folate. Vitamin A and carotenoid metabolism in chickens is closely related to the equivalent processes in humans. Consequently chickens are also susceptible to vitamin A deficiency with similar symptoms.
Is part ofInformation Systems for Biotechnology (ISB) News Report, 2015, p. 8-11
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High-carotenoid maize: development of plant biotechnology prototypes for human and animal health and nutrition Zhu, Changfu; Farré Martinez, Gemma; Zanga, Daniela; Lloveras Vilamanyà, Jaume; Michelena Bárcena, Antonio; Ferrio Díaz, Juan Pedro; Voltas Velasco, Jordi; Slafer, Gustavo A.; Savin, Roxana; Albajes Garcia, Ramon; Eizaguirre Altuna, Matilde; López Alonso, Carmen; Cantero-Martínez, Carlos; Díaz Gómez, Joana; Nogareda, Carmina; Moreno Martínez, José Antonio; Angulo Asensio, Eduardo; Estany Illa, Joan; Pena i Subirà, Ramona Natacha; Tor i Naudí, Marc; Portero Otín, Manuel; Eritja Sánchez, Núria; Arjó Pont, Gemma; Serrano Casasola, José Carlos Enrique; Matias-Guiu, Xavier; Twyman, Richard M.; Sandmann, Gerhard; Capell Capell, Teresa; Christou, Paul (Springer Verlag, 2017-06-01)Carolight® is a transgenic maize variety that accumulates extraordinary levels of carotenoids, including those with vitamin A activity. The development of Carolight® maize involved the technical implementation of a novel ...
Díaz Gómez, Joana; Moreno Martínez, José Antonio; Angulo Asensio, Eduardo; Sandmann, Gerhard; Zhu, Changfu; Ramos Girona, Antonio J.; Capell Capell, Teresa; Christou, Paul; Nogareda, Carmina (Elsevier B.V., 2017-06-12)Skin color in poultry is achieved by the addition of natural or synthetic pigments to feed. Crops used routinely in feed formulations offer an alternative cost-effective strategy to replace color additives if they are ...
Carotenoid-enriched transgenic corn delivers bioavailable carotenoids to poultry and protects them against coccidiosis Nogareda, Carmina; Moreno, José A.; Angulo Asensio, Eduardo; Sandmann, Gerhard; Portero Otín, Manuel; Capell Capell, Teresa; Zhu, Changfu; Christou, Paul (John Wiley & SonsWiley-Blackwell, 2015)Carotenoids are health-promoting organic molecules that act as antioxidants and essential nutrients. We show that chickens raised on a diet enriched with an engineered corn variety containing very high levels of four key ...