A summary of the study of Aphis illinoisensis Shimer on grapes, Vitis vinifera in the Mediterranean area brings references and new findings on its distribution in Crete/Greece, Turkey, Northern Cyprus, Malta, Israel, Montenegro, Tunisia, Algeria and Libya. Parasitoids of A. illinoisensis were only occasionally found (Aphidius matricariae Hal. – Cyprus, Turkey, Greece; Aphidius colemani Viereck – Libya; Lysiphlebus testaceipes Cress. – Algeria). Of the native species, i.e. A. colemani, and others similar to the native species, L. testaceipes seem to be a promising biocontrol agent within the framework of an ecologically friendly management in the area. Given the evidence of its expansion, A. illinoisensis is expected to expand further in several directions from the recently documented invaded area to all the grape-growing areas of the Mediterranean and even those of South-Eastern and Central Europe.