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dc.contributor.authorGonzález-Candelas, Fernando
dc.contributor.authorAstray, Jenaro
dc.contributor.authorAlonso, Jordi
dc.contributor.authorCastro, Ady
dc.contributor.authorCantón, Rafael
dc.contributor.authorGalán, Juan Carlos
dc.contributor.authorGarín, Olatz
dc.contributor.authorSáez, Marc
dc.contributor.authorSoldevila, Núria
dc.contributor.authorBaricot, Maretva
dc.contributor.authorCastilla, Jesús
dc.contributor.authorGodoy i García, Pere
dc.contributor.authorDelgado-Rodríguez, Miguel
dc.contributor.authorMartín, Vicente
dc.contributor.authorMayoral, José María
dc.contributor.authorPumarola, Tomás
dc.contributor.authorQuintana, José María
dc.contributor.authorTamames, Sonia
dc.contributor.authorDomínguez García, Àngela
dc.contributor.authorCIBERESP Cases and Controls in Pandemic Influenza Working Group
dc.description.abstractThe emergence and pandemic spread of a new strain of influenza A (H1N1) virus in 2009 resulted in a serious alarm in clinical and public health services all over the world. One distinguishing feature of this new influenza pandemic was the different profile of hospitalized patients compared to those from traditional seasonal influenza infections. Our goal was to analyze sociodemographic and clinical factors associated to hospitalization following infection by influenza A(H1N1) virus. We report the results of a Spanish nationwide study with laboratory confirmed infection by the new pandemic virus in a case-control design based on hospitalized patients. The main risk factors for hospitalization of influenza A (H1N1) 2009 were determined to be obesity (BMI$40, with an odds-ratio [OR] 14.27), hematological neoplasia (OR 10.71), chronic heart disease, COPD (OR 5.16) and neurological disease, among the clinical conditions, whereas low education level and some ethnic backgrounds (Gypsies and Amerinds) were the sociodemographic variables found associated to hospitalization. The presence of any clinical condition of moderate risk almost triples the risk of hospitalization (OR 2.88) and high risk conditions raise this value markedly (OR 6.43). The risk of hospitalization increased proportionally when for two (OR 2.08) or for three or more (OR 4.86) risk factors were simultaneously present in the same patient. These findings should be considered when a new influenza virus appears in the human population.ca_ES
dc.publisherPublic Library of Scienceca_ES
dc.relation.isformatofReproducció del document publicat a
dc.relation.ispartofPLoS One, 2012, vol. 7, núm. 3, e33139ca_ES
dc.rightscc-by, (c) González-Candelas et al., 2012ca_ES
dc.titleSociodemographic factors and clinical conditions associated to hospitalization in influenza A (H1N1) 2009 virus infected patients in Spain, 2009–2010ca_ES

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cc-by, (c) González-Candelas et al., 2012
Except where otherwise noted, this item's license is described as cc-by, (c) González-Candelas et al., 2012