Faecal microbial metabolism of olive oil phenolic compounds: in-vitro and in-vivo approaches

Mosele, Juana; Martín Peláez, Sandra María; Macià i Puig, Ma Alba; Farràs, Marta; Valls, Rosa M.; Catalán Santos, Úrsula; Motilva Casado, Mª José

doi:https://doi.org/10.1002/mnfr.201400124

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Sol·licita una còpia

Issue date

2014

Author

Mosele, Juana

Martín Peláez, Sandra María

Macià i Puig, Ma Alba

Farràs, Marta

Valls, Rosa M.

Catalán Santos, Úrsula

Motilva Casado, Mª José

Abstract

In the present study, the individual colonic metabolism of the main components of the virgin olive oil phenolic fraction was evaluated by an in vitro model using human faecal microbiota. To assess differences in metabolism related to the molecular structure, four phenolic standards were selected, tyrosol,

hydroxytyrosol, hydroxytyrosol acetate and oleuropein. After studying the in vitro colonic metabolism pathways of the individual phenols, the presence of their colonic metabolites was investigated in human faecal samples obtained before and after the sustained intake (3 weeks) of a daily dose of 25 mL of a phenol-enriched olive oil.

URI

http://hdl.handle.net/10459.1/47508

DOI

https://doi.org/10.1002/mnfr.201400124

Is part of

Molecular Nutrition & Food Research, 2014, vol. 58, núm. 9, p. 1809-1819