Faecal microbial metabolism of olive oil phenolic compounds: in-vitro and in-vivo approaches

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2014
Author
Mosele, Juana
Martín Peláez, Sandra María
Macià i Puig, Ma Alba
Farràs, Marta
Valls, Rosa M.
Catalán Santos, Úrsula
Motilva Casado, Mª José
Suggested citation
Mosele, Juana; Martín Peláez, Sandra María; Macià i Puig, Ma Alba; Farràs, Marta; Valls, Rosa M.; Catalán Santos, Úrsula; Motilva Casado, Mª José; . (2014) . Faecal microbial metabolism of olive oil phenolic compounds: in-vitro and in-vivo approaches. Molecular Nutrition & Food Research, 2014, vol. 58, núm. 9, p. 1809-1819. https://doi.org/10.1002/mnfr.201400124.
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Abstract
In the present study, the individual colonic metabolism of the main components of the virgin olive oil phenolic fraction was evaluated by an in vitro model using human faecal microbiota. To assess differences in metabolism related to the molecular structure, four phenolic standards were selected, tyrosol, hydroxytyrosol, hydroxytyrosol acetate and oleuropein. After studying the in vitro colonic metabolism pathways of the individual phenols, the presence of their colonic metabolites was investigated in human faecal samples obtained before and after the sustained intake (3 weeks) of a daily dose of 25 mL of a phenol-enriched olive oil.
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http://hdl.handle.net/10459.1/47508
DOI
https://doi.org/10.1002/mnfr.201400124
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Molecular Nutrition & Food Research, 2014, vol. 58, núm. 9, p. 1809-1819
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