Now showing items 1-2 of 2

    • Developmental silencing and independency from E2F of apoptotic gene expression in postmitotic tissues 

      Zhang, Jisheng; Bahi i Pla, Núria; Zubiaga, Ana M.; Comella i Carnicé, Joan Xavier; Llovera i Tomàs, Marta; Sanchis, Daniel (Wiley, 2007)
      The involvement of caspases in postmitotic cell death is controversial. Here we report that adult brain and heart are devoid of many key pro-apoptotic proteins due to a progressive postnatal silencing event involving a ...
    • Executioner Caspase-3 and 7 Deficiency Reduces Myocyte Number in the Developing Mouse Heart 

      Cardona, Maria; López, Juan Antonio; Serafín, Anna; Rongvaux, Anthony; Inserte Igual, Javier; García-Dorado, David; Flavell, Richard; Llovera i Tomàs, Marta; Cañas, Xavier; Vázquez, Jesús; Sanchis, Daniel (Public Library of Science, 2015-06-29)
      Executioner caspase-3 and -7 are proteases promoting cell death but non-apoptotic roles are being discovered. The heart expresses caspases only during development, suggesting they contribute to the organ maturation process. ...