Browsing Institut de Recerca Biomèdica de Lleida (IRBLleida) by Subject "Degradation"

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Ubiquitination of TrkA by Nedd4-2 regulates receptor lysosomal targeting and mediates receptor signaling

Georgieva, Maya V.; Pablo Llavall, Yolanda de; Sanchis, Daniel; Comella i Carnicé, Joan Xavier; Llovera i Tomàs, Marta (Wiley, 2011)

The nerve growth factor receptor TrkA (tropomyosin-related kinase receptor) participates in the survival and differentiation of several neuronal populations. The C-terminal tail of TrkA contains a PPXY motif, the binding ...