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    • The PDK1 Inhibitor Dichloroacetate Controls Cholesterol Homeostasis Through the ERK5/MEF2 Pathway 

      Khan, Abrar Ul Haq; Allende-Vega, Nerea; Gitenay, Delphine; Gerbal-Chaloin, Sabine; Gondeau, Claire; Vo, Dang-Nghiem; Belkahla, Sana; Orecchioni, Stefania; Talarico, Giovanna; Bertolini, Francesco; Bozić Stanojević, Milica; Valdivielso Revilla, José Manuel; Bejjani, Fabienne; Jariel, Isabelle; Lopez-Mejia, Isabel C.; Fajas, Lluis; Lecellier, Charles-Henri; Hernandez, Javier; Daujat, Martine; Villalba, Martin (Nature Publishing Group, 2017)
      Controlling cholesterol levels is a major challenge in human health, since hypercholesterolemia can lead to serious cardiovascular disease. Drugs that target carbohydrate metabolism can also modify lipid metabolism and ...