Now showing items 1-3 of 3

    • Gremlin Regulates Tubular Epithelial to Mesenchymal Transition via VEGFR2: Potential Role in Renal Fibrosis 

      Marquez Exposito, Laura; Lavoz, Carolina; Rodrigues-Diez, Raul; Rayego Mateos, Sandra; Orejudo, Macarena; Cantero-Navarro, Elena; Ortiz, Alberto; Egido, Jesús; Selgas, Rafael; Mezzano, Sergio; Ruiz-Ortega, Marta (Frontiers Media, 2018)
      Chronic kidney disease (CKD) is emerging as an important health problem due to the increase number of CKD patients and the absence of an effective curative treatment. Gremlin has been proposed as a novel therapeutic target ...
    • IL-17A as a potential therapeutic target for patients on peritoneal dialysis 

      Marchant, Vanessa; Tejera Muñoz, Antonio; Marquez Exposito, Laura; Rayego Mateos, Sandra; Rodrigues-Diez, Raul; Tejedor, Lucia; Santos Sanchez, Laura; Egido, Jesús; Valdivielso Revilla, José Manuel; Fraser, Donald J.; López Cabrera, Manuel; Selgas, Rafael; Ruiz-Ortega, Marta (MDPI, 2020)
      Chronic kidney disease (CKD) is a health problem reaching epidemic proportions. There is no cure for CKD, and patients may progress to end-stage renal disease (ESRD). Peritoneal dialysis (PD) is a current replacement therapy ...
    • Interleukin-17A: Potential mediator and therapeutic target in hypertension 

      Rodrigues-Diez, Raul; Tejera Muñoz, Antonio; Orejudo, Macarena; Marquez Exposito, Laura; Santos Sanchez, Laura; Rayego Mateos, Sandra; Cantero-Navarro, Elena; Tejedor, Lucia; Marchant, Vanessa; Ortiz, Alberto; Egido, Jesús; Mezzano, Sergio; Selgas, Rafael; Navarro González, Juan F.; Valdivielso Revilla, José Manuel; Lavoz, Carolina; Ruiz-Ortega, Marta (Elsevier, 2021)
      Interleukin-17A (IL-17A) is a proinflammatory cytokine produced by cells of the immunesystem, predominantly Th17 and lymphocytes. In this paper, we review the role of IL-17A in the pathogenesis of hypertension and in ...