Now showing items 1-4 of 4

    • Acetylsalicylic acid prevents intermittent hypoxia-induced vascular remodeling in a murine model of sleep apnea 

      Suarez-Giron, Monique C.; Castro-Grattoni, Anabel L.; Torres, Marta; Farré, Ramon; Barbé Illa, Ferran; Sánchez de la Torre, Manuel; Gozal, David; Picado, Cesar; Montserrat i Capdevila, Josep; Almendros, Isaac (Frontiers Media, 2018)
      Study objectives: Chronic intermittent hypoxia (CIH), a hallmark feature of obstructive sleep apnea (OSA), induces accelerated atherogenesis as well as aorta vascular remodeling. Although the cyclooxygenase (COX) pathway ...
    • Documento internacional de consenso sobre apnea obstructiva del sueño 

      Mediano, Olga; González Mangado, Nicolas; Montserrat, Josep Maria; Alonso Álvarez, María Luz; Almendros, Isaac; Alonso Fernández, Alberto; Barbé Illa, Ferran; Borsini, Eduardo; Caballero-Eraso, Candela; Cano-Pumarega, Irene; Carlos Villafranca, Felix Antonio De; Carmona Bernal, Carmen; Carrillo Alduenda, Jose Luis; Chiner, Eusebi; Cordero Guevara, Jose Aurelio; de Manuel, Luis; Durán-Cantolla, Joaquín; Farré, Ramon; Franceschini, Carlos; Gaig, Carles; García Ramos, Pedro; García-Río, Francisco; Garmendia, Onintza; Gómez García, Teresa; González Pondal, Silvia; Hoyo Rodrigo, Blanca M.; Lecube Torelló, Albert; Madrid, Juan Antonio; Maniegas Lozano, Lourdes; Martínez Carrasco, José Luis; Masa, Juan Fernando; Masdeu, María José; Mayós Pérez, Mercè; Mirabet Lis, Enrique; Monasterio, Carmen; Navarro Soriano, Nieves; Olea de la Fuente, Erika; Plaza, Guillermo; Puertas Cuesta, Francisco Javier; Rabec, Claudio; Resano, Pilar; Rigau, David; Roncero, Alejandra; Ruiz, Concepción; Salord, Neus; Saltijeral, Adriana; Sampol, Gabriel; Sánchez Quiroga, María Ángeles; Sans Capdevila, Oscar; Teixeira, Carlos; Tinahones, Francisco José; Togeiro, Sonia María; Troncoso Acevedo, Maria Fernanda; Vargas Ramírez, Leslie Katherine; Winck, Joao; Zabala Urionaguena, Nerea; Egea, Carlos (Elsevier, 2021)
      Themainaimofthis international consensusdocument onobstructive sleepapnea is toprovide guidelines based on a critical analysis of the latest literature to help health professionals make the best decisions in the care of ...
    • Intermittent Hypoxia Is Associated With High Hypoxia Inducible Factor-1α but Not High Vascular Endothelial Growth Factor Cell Expression in Tumors of Cutaneous Melanoma Patients 

      Almendros, Isaac; Martínez-García, Miguel Angel; Campos-Rodríguez, Francisco; Riveiro-Falkenbach, Erica; Rodríguez-Peralto, José L.; Nagore, Eduardo; Martorell-Calatayud, Antonio; Hernández Blasco, Luis; Bañuls Roca, Jose; Chiner, Eusebi; Sánchez de la Torre, Alicia; Abad, Jorge; Montserrat, Josep Maria; Pérez-Gil, Amalia; Cabriada, Valentín; Cano-Pumarega, Irene; Corral-Peñafiel, Jaime; Diaz-Cambriles, Trinidad; Mediano, Olga; Dalmau-Arias, Joan; Farré, Ramon; Gozal, David; Spanish Sleep Network (Frontiers Media, 2018)
      Epidemiological associations linking between obstructive sleep apnea and poorer solid malignant tumor outcomes have recently emerged. Putative pathways proposed to explain that these associations have included enhanced ...
    • Obesity attenuates the effect of sleep apnea on active TGF-ß1 levels and tumor aggressiveness in patients with melanoma 

      Cubillos‑Zapata, Carolina; Martínez‑García, Miguel Ángel; Díaz‑García, Elena; Jaureguizar, Ana; Campos‑Rodríguez, Francisco; Sánchez de la Torre, Manuel; Nagore, Eduardo; Martorell‑Calatayud, Antonio; Hernández Blasco, Luis; Pastor, Esther; Abad, Jorge; Montserrat, Josep Maria; Cabriada‑Nuño, Valentín; Cano‑Pumarega, Irene; Corral-Peñafiel, Jaime; Arias, Eva; Mediano, Olga; Somoza, María; Dalmau-Arias, Joan; Almendros, Isaac; Farré, Ramon; López‑Collazo, Eduardo; Gozal, David; García Río, Francisco (Nature Research, 2020)
      Active transforming growth factor-β1 (TGF-β1), a cytokine partially regulated by hypoxia and obesity, has been related with poor prognosis in several tumors. We determine whether obstructive sleep apnea (OSA) increases ...