Now showing items 1-8 of 8

    • A salmon peptide diet alleviates experimental colitis as compared with fish oil 

      Grimstad, Tore; Bjørndal, Bodil; Cacabelos Barral, Daniel; Aasprong, Ole G.; Omdal, Roald; Svardal, Asbjørn; Bohov, Pavol; Pamplona Gras, Reinald; Portero Otín, Manuel; Berge, Rolf K.; Hausken, Trygve (Cambridge University Press, 2013)
      Fish oil (FO) has been shown to have anti-inflammatory properties in animal models of inflammatory bowel disease, but how fish peptides (FP) influence intestinal inflammation has been less studied. Male Wistar rats, divided ...
    • Calpain activation and CaMKIV reduction in spinal cords from hSOD1G93A mouse model 

      Gou Fabregas, Myriam; Ramírez-Núñez, Omar; Cacabelos Barral, Daniel; Bahi i Pla, Núria; Portero Otín, Manuel; Garcera, Ana; Soler i Tatché, Rosa Ma. (Elsevier, 2014)
      Amyotrophic Lateral Sclerosis (ALS), a severe neurodegenerative disease, affects the upper and lower motor neurons in the brain and spinal cord. In some studies, ALS disease progression has been associatedwith an increase ...
    • Dietary Lipid Unsaturation Influences Survival and Oxidative Modifications of an Amyotrophic Lateral Sclerosis Model in a Gender-Specific Manner 

      Cacabelos Barral, Daniel; Ayala Jové, Ma. Victoria (Maria Victoria); Ramírez-Núñez, Omar; Granado-Serrano, Ana Belén; Boada Pallàs, Jordi; Serrano Casasola, José Carlos Enrique; Cabré Cucó, Rosanna; Nadal Rey, Gisela; Bellmunt i Curcó, Josepa; Ferrer, Isidre; Pamplona Gras, Reinald; Portero Otín, Manuel (Springer, 2014)
      The implication of lipid peroxidation in neurodegenerative diseases, including amyotrophic lateral sclerosis (ALS) derive from high abundance of peroxidation- prone polyunsaturated fatty acids in central nervous system ...
    • Early and gender-specific differences in spinal cord mitochondrial function and oxidative stress markers in a mouse model of ALS 

      Cacabelos Barral, Daniel; Ramírez-Núñez, Omar; Granado-Serrano, Ana Belén; Torres Cabestany, Pascual; Ayala Jové, Ma. Victoria (Maria Victoria); Moiseeva, Victoria; Povedano, Mònica; Ferrer, Isidre; Pamplona Gras, Reinald; Portero Otín, Manuel; Boada Pallàs, Jordi (BioMed Central, 2016)
      Introduction: Amyotrophic lateral sclerosis (ALS) is a motor neuron disease with a gender bias towards major prevalence in male individuals. Several data suggest the involvement of oxidative stress and mitochondrial dysfunction ...
    • Formation of S-(carboxymethyl)-cysteine in rat liver mitochondrial proteins: effects of caloric and methionine restriction 

      Naudí i Farré, Alba; Jové Font, Mariona; Cacabelos Barral, Daniel; Ayala Jové, Ma. Victoria (Maria Victoria); Cabré Cucó, Rosanna; Caro, Pilar; Gomez, José; Portero Otín, Manuel; Barja, Gustavo; Pamplona Gras, Reinald (Springer Verlag, 2013)
      Maillard reaction contributes to the chemical modification and cross-linking of proteins. This process plays a significant role in the aging process and determination of animal longevity. Oxidative conditions promote the ...
    • Impaired mitochondrial oxidative phosphorylation in the peroxisomal disease X-linked adrenoleukodystrophy 

      López Erauskin, Jone; Galino, Jorge; Ruiz, M.; Cuezva, J. M.; Fabregat, I.; Cacabelos Barral, Daniel; Boada Pallàs, Jordi; Martínez, Juan José; Ferrer, Isidre; Pamplona Gras, Reinald; Villarroya, Francesc; Portero Otín, Manuel; Fourcade, Stéphane; Pujol, A. (Oxford Journals, 2013)
      X-linked adrenoleukodystrophy (X-ALD) is an inherited metabolic disorder of the nervous system characterized by axonopathy in spinal cords and/or cerebral demyelination, adrenal insufficiency and accumulation of very ...
    • Lipidome analysis in multiple sclerosis reveals protein lipoxidative damage as a potential pathogenic mechanism 

      Gonzalo Benito, Hugo; Brieva Ruiz, Luis; Tatzber, Franz; Jové Font, Mariona; Cacabelos Barral, Daniel; Cassanyé, Anna; Lanau, Lucia; Boada Pallàs, Jordi; Serrano Casasola, José Carlos Enrique; González Mingot, Cristina; Hernández, Lourdes; Peralta Moncusí, Silvia; Pamplona Gras, Reinald; Portero Otín, Manuel (Wiley, 2012)
      Metabolomic and lipidomic analyses have been used for the profiling of neurodegenerative processes, both in targeted and untargeted approaches. In this work we have applied these techniques to the study of CSF samples of ...
    • Plant-derived phenolics inhibit the accrual of structurally characterised protein and lipid oxidative modifications 

      Soler Cantero, Arantza; Jové Font, Mariona; Cacabelos Barral, Daniel; Boada Pallàs, Jordi; Naudí i Farré, Alba; Romero Fabregat, Mª Paz; Cassanyé, Anna; Serrano Casasola, José Carlos Enrique; Arola i Ferrer, Lluís; Valls, Josep; Bellmunt i Curcó, Josepa; Prat Corominas, Joan; Pamplona Gras, Reinald; Portero Otín, Manuel; Motilva Casado, Mª José (Public Library of Science, 2012)
      Epidemiological data suggest that plant-derived phenolics beneficial effects include an inhibition of LDL oxidation. After applying a screening method based on 2,4-dinitrophenyl hydrazine- protein carbonyl reaction to 21 ...