Now showing items 1-8 of 8

    • Addition of IMP3 to L1CAM for discrimination between low- and high-grade endometrial carcinomas: a European Network for Individualised Treatment of Endometrial Cancer collaboration study 

      Visser, Nicole C.M.; van der Putten, Louis J. M.; van Egerschot, Alex; van de Vijver, Koen; Santacana Espasa, Maria; Bronsert, Peter; Hirschfeld, Marc; Colás, Eva; Colás, Eva; Gil-Moreno, Antonio; Garcia, Angel; Mancebo, Gemma; Alameda, Fransesc; Krakstad, Camilla; Tangen, Ingvild L.; Huvila, Jutta; Schrauwen, Stefanie; Koskas, Martin; Walker, Francine; Weinberger, Vit; Minar, Lubos; Hausnerova, Jitka; Snijders, Marc P. L. M.; van den Berg-van Erp, Saskia; Matias-Guiu, Xavier; Trovik, Jone; Amant, Frederic; Massuger, Leon F. A. G.; Bulten, Johan; Pijnenborg, Johanna M. A. (Elsevier, 2019)
      Discrimination between low- and high-grade endometrial carcinomas (ECs) is clinically relevant but can be challenging for pathologists, with moderate interobserver agreement. Insulin-like growth factor-II mRNA-binding ...
    • Immunohistochemical biomarkers are prognostic relevant in addition to the ESMO-ESGO-ESTRO risk classification in endometrial cancer 

      Vrede, S. W.; Van Weelden, Willem Jan; Visser, N. C. M.; Bulten, Johan; van der Putten, Louis J. M.; van de Vijver, Koen; Santacana Espasa, Maria; Colàs Campàs, Laura; Gil-Moreno, Antonio; Moiola, Cristian P.; Mancebo, Gemma; Krakstad, Camilla; Trovik, Jone; Haldorsen, Ingfrid S.; Huvila, Jutta; Koskas, Martin; Weinberger, Vit; Bednarikova, M.; Hausnerova, Jitka; van der Wurff, Anneke A. M.; Matias-Guiu, Xavier; Amant, Frederic; ENITEC Consortium; Snijders, Marc P. L. M.; Küsters-Vandevelde, Heidi V. N; Reijnen, Casper; Pijnenborg, Johanna M. A. (Elsevier, 2021)
      Objective Pre-operative immunohistochemical (IHC) biomarkers are not incorporated in endometrial cancer (EC) risk classification. We aim to investigate the added prognostic relevance of IHC biomarkers to the ESMO-ESGO-ESTRO ...
    • L1CAM expression in endometrial carcinomas: an ENITEC collaboration study 

      van der Putten, Louis J. M.; Visser, Nicole C.M.; van de Vijver, Koen; Santacana Espasa, Maria; Bronsert, Peter; Bulten, Johan; Hirschfeld, Marc; Colás, Eva; Gil-Moreno, Antonio; Garcia, Angel; Mancebo, Gemma; Alameda, Fransesc; Trovik, Jone; Kopperud, Reidun K.; Huvila, Jutta; Schrauwen, Stefanie; Koskas, Martin; Walker, Francine; Weinberger, Vit; Minar, Lubos; Jandakova, Eva; Snijders, Marc P. L. M.; van den Berg-van Erp, Saskia; Matias-Guiu, Xavier; Salvesen, Helga B.; Amant, Frederic; Massuger, Leon F. A. G.; Pijnenborg, Johanna M. A. (Springer Nature, 2016)
      Background: Identification of aggressive endometrioid endometrial carcinomas (EECs) and non-endometrioid carcinomas (NEECs) is essential to improve outcome. L1 cell adhesion molecule (L1CAM) expression is a strong prognostic ...
    • Poor outcome in hypoxic endometrial carcinoma is related to vascular density 

      Reijnen, Casper; Van Weelden, Willem Jan; Arts, Martijn S. J. P.; Peters, Johan P.; Rijken, Paul F.; van de Vijver, Koen; Santacana Espasa, Maria; Bronsert, Peter; Bulten, Johan; Hirschfeld, Marc; Colás, Eva; Gil-Moreno, Antonio; Reques, Armando; Mancebo, Gemma; Krakstad, Camilla; Trovik, Jone; Haldorsen, Ingfrid S; Huvila, Jutta; Koskas, Martin; Weinberger, Vit; Minar, Lubos; Jandakova, Eva; Snijders, Marc P. L. M.; van den Berg-van Erp, Saskia; Küsters-Vandevelde, Heidi V. N; Matias-Guiu, Xavier; Amant, Frederic; Massuger, Leon F. A. G.; Bussink, Johan; Pijnenborg, Johanna M. A. (Springer Nature; Cancer Research UK, 2019)
      BACKGROUND: Identification of endometrial carcinoma (EC) patients at high risk of recurrence is lacking. In this study, the prognostic role of hypoxia and angiogenesis was investigated in EC patients. METHODS: Tumour ...
    • Preoperative risk stratification in endometrial cancer (ENDORISK) by a Bayesian network model: A development and validation study 

      Reijnen, Casper; Gogou, Evangelia; Visser, Nicole C. M.; Engerud, Hilde; Ramjith, Jordache; van der Putten, Louis J. M.; van de Vijver, Koen; Santacana, Maria; Bronsert, Peter; Bulten, Johan; Hirschfeld, Marc; Colas, Eva; Gil-Moreno, Antonio; Reques, Armando; Mancebo, Gemma; Krakstad, Camilla; Trovik, Jone; Haldorsen, Ingfrid S.; Huvila, Jutta; Koskas, Martin; Weinberger, Vit; Bednarikova, Marketa; Hausnerova, Jitka; van der Wurff, Anneke A. M.; Matias-Guiu, Xavier; Amant, Frederic; Massuger, Leon F. A. G.; Snijders, Marc P. L. M.; Küsters-Vandevelde, Heidi V. N; Lucas, Peter J. F.; Pijnenborg, Johanna M. A. (Public Library of Science, 2020-05)
      Background Bayesian networks (BNs) are machine-learning–based computational models that visualize causal relationships and provide insight into the processes underlying disease progression, closely resembling clinical ...
    • Reproducibility of measurement of myometrial invasion in endometrial carcinoma 

      van der Putten, Louis J. M.; van de Vijver, Koen; Bartosch, Carla; Davidson, Ben; Gatius Calderó, Sònia; Matias-Guiu, Xavier; McCluggage, W. Glenn; Toledo, Gemma; van der Wurff, Anneke A. M.; Pijnenborg, Johanna M. A.; Massuger, Leon F. A. G.; Bulten, Johan (Springer Berlin Heidelberg, 2016)
      Myometrial invasion (MI) as a percentage (%MI), categorized into <50 or ≥50 %, is an important predictor of prognosis in endometrial carcinoma. Recent studies suggest that tumor-free distance (TFD) to serosa and the absolute ...
    • The amount of preoperative endometrial tissue surface in relation to final endometrial cancer classification 

      Vrede, S.W.; Hulsman, A.M.C.; Colás, Eva; Mancebo, Gemma; Moiola, Cristian P.; Reijnen, Caspe; van de Vijver, Koen; Gil-Moreno, Antonio; Huvila, Jutta; Koskas, Martin; Weinberger, Vit; Minar, Lubos; Jandakova, Eva; Santacana Espasa, Maria; Matias-Guiu, Xavier; Amant, Frederic; Snijders, Marc P. L. M.; Küsters-Vandevelde, Heidi V. N; Bulten, Johan; Pijnenborg, Johanna M. A. (Elsevier, 2022)
      Objective: To evaluate whether the amount of preoperative endometrial tissue surface is related to the degree of concordance with final low- and high-grade endometrial cancer (EC). In addition, to determine whether discordance ...
    • The cutoff for estrogen and progesterone receptor expression in endometrial cancer revisited: a European Network for Individualized Treatment of Endometrial Cancer collaboration study 

      Van Weelden, Willem Jan; Reijnen, Casper; Küsters-Vandevelde, Heidi V. N; Bulten, Johan; Bult, Peter; Leung, Samuel; Visser, N. C. M.; Santacana Espasa, Maria; Bronsert, Peter; Hirschfeld, Marc; Colás, Eva; Gil-Moreno, Antonio; Reques, Armando; Mancebo, Gemma; Huvila, Jutta; Koskas, Martin; Weinberger, Vit; Bednarikova, M.; Hausnerova, Jitka; Snijders, Marc P. L. M.; Matias-Guiu, Xavier; Amant, Frederic (Elsevier, 2021)
      There is no consensus on the cutoff for positivity of estrogen receptor (ER) and progesterone receptor (PR) in endometrial cancer (EC). Therefore, we determined the cutoff value for ER and PR expression with the strongest ...