Now showing items 675-694 of 913

    • Proposal for the creation of a national strategy for precision medicine in cancer: a position statement of SEOM, SEAP and SEFH 

      Garrido, Pilar; Aldaz, Azucena; Calleja, Miguel Ángel; Álava, Enrique de; Lamas, María Jesús; Martín, Miguel; Matias-Guiu, Xavier; Palacios, José; Vera, Ruth (Aula Médica Ediciones, 2017)
      Precision medicine is an emerging approach for disease treatment and prevention that takes into account individual variability in genes, environment, and lifestyle for each person. Precision medicine is transforming ...
    • Proposal for the creation of a national strategy for precision medicine in cancer: a position statement of SEOM, SEAP,and SEFH 

      Garrido, Pilar; Aldaz, Azucena; Vera, Ruth; Calleja, Miguel Ángel; Álava, Enrique de; Martín, Miguel; Matias-Guiu, Xavier; Palacios, José (Springer, 2018)
      Precision medicine is an emerging approach for disease treatment and prevention that takes into account individual variability in genes, environment, and lifestyle for each person. Precision medicine is transforming ...
    • Prostate-targeted radiosensitization via aptamer-shRNA chimeras in human tumor xenografts 

      Ni, Xiaohua; Zhang, Yonggang; Ribas i Fortuny, Judit; Chowdhury, Wasim H.; Castanares, Mark; Zhang, Zhewei; Laiho, Marikki; DeWeese, Theodore L.; Lupold, Shawn E. (American Society for Clinical Investigation, 2011)
      Dose-escalated radiation therapy for localized prostate cancer (PCa) has a clear therapeutic benefit; however, escalated doses may also increase injury to noncancerous tissues. Radiosensitizing agents can improve ...
    • Protective role of renal proximal tubular alpha-synuclein in the pathogenesis of kidney fibrosis 

      Bozić Stanojević, Milica; Caus Enríquez, Maite; Rodrigues-Diez, Raul; Pedraza González, Neus; Ruiz-Ortega, Marta; Garí Marsol, Eloi; Gallel Vicente, María del Pilar; Panadés, Maria José; Martinez, Ana; Fernández i Giráldez, Elvira; Valdivielso Revilla, José Manuel (Nature Publishing Group, 2020)
      Kidney fibrosis is a highly deleterious process and a final manifestation of chronic kidney disease. Alpha-(α)-synuclein (SNCA) is an actin-binding neuronal protein with various functions within the brain; however, its ...
    • Protein carbonylation: proteomics, specificity and relevance to aging 

      Cabiscol Català, Elisa; Tamarit Sumalla, Jordi; Ros Salvador, Joaquim (Wiley, 2013)
      Detection and quantification of protein carbonyls present in biological samples has become a popular, albeit indirect, method to determine the existence of oxidative stress. Moreover, the rise of proteomics has allowed ...
    • Protein Kinase KIS Localizes to RNA Granules and Enhances Local Translation 

      Cambray Carner, Serafí; Pedraza González, Neus; Rafel i Borrell, Marta; Garí Marsol, Eloi; Aldea, Martí; Gallego, Carme (American Society for Microbiology, 2009)
      The regulation of mRNA transport is a fundamental process for cytoplasmic sorting of transcripts and spatially controlled translational derepression once properly localized. There is growing evidence that translation is ...
    • Protein oxidation in Huntington disease 

      Sorolla Bardají, Maria Alba; Rodríguez Colman, Maria José; Vall-llaura Espinosa, Núria; Tamarit Sumalla, Jordi; Ros Salvador, Joaquim; Cabiscol Català, Elisa (Wiley, 2012-05)
      Huntington disease (HD) is an inherited neurodegenerative disorder caused by expansion of CAG repeats in the huntingtin gene, affecting initially the striatum and progressively the cortex. Oxidative stress, and consequent ...
    • Protein oxidation in Huntington disease affects energy production and vitamin B6 metabolism 

      Sorolla Bardají, Maria Alba; Rodríguez Colman, Maria José; Tamarit Sumalla, Jordi; Ortega, Zaira; Lucas, José J.; Ferrer, Isidre; Ros Salvador, Joaquim; Cabiscol Català, Elisa (Elsevier, 2010)
      Huntington disease (HD) is an inherited neurodegenerative disorder that initially affects the striatum and progressively the cortex. Oxidative stress in HD has been described as important to disease progression. In ...
    • Protein targets of oxidative damage in human neurodegenerative diseases with abnormal protein aggregates 

      Martínez, Anna; Portero Otín, Manuel; Pamplona Gras, Reinald; Ferrer, Isidre (Wiley, 2010)
      Human neurodegenerative diseases with abnormal protein aggregates are associated with aberrant post-translational modifications, solubility, aggregation and fibril formation of selected proteins which cannot be degraded ...
    • Proteomic and oxidative stress analysis in human brain samples of Huntington disease 

      Sorolla Bardají, Maria Alba; Reverter Branchat, Gemma; Tamarit Sumalla, Jordi; Ferrer, Isidre; Ros Salvador, Joaquim; Cabiscol Català, Elisa (Elsevier, 2008)
      Huntington disease (HD) is a neurodegenerative disorder caused by expansion of CAG repeats in exon 1 of the huntingtin gene, affecting initially the striatum and progressively the cortex. This work reports a proteomic analysis ...
    • Pseudophakic cystoid macular edema: update 2016 

      Grzybowski, Andrzej; Sikorski, Bartosz L; Ascaso, Francisco J.; Huerva, Valentín (Dovepress, 2016)
      Pseudophakic cystoid macular edema (PCME) is the most common complication of cataract surgery, leading in some cases to a decrease in vision. Although the pathogenesis of PCME is not completely understood, the contribution ...
    • Psoriasis, metabolic syndrome and cardiovascular risk factors. A population-based study. 

      Fernández Armenteros, José Manuel; Gómez Arbonés, Javier; Buti, Miquel; Betriu i Bars, M. Àngels; Sanmartín Novell, Verònica; Ortega Bravo, Marta; Martínez Alonso, Montserrat; Garí Marsol, Eloi; Portero Otín, Manuel; Santamaria-Babi, L.; Casanova i Seuma, Josep M. (Josep Manel) (Wiley, 2019)
      Abstract Background: Psoriasis is a very prevalent systemic chronic inflammatory disease. Major cardiovascular events are the main cause of mortality in these patients which suggests an association between psoriasis and ...
    • Psychological Well-Being in Nursing Students: A Multicentric, Cross-Sectional Study 

      Reverté-Villarroya, Sílvia; Ortega, Laura; Raigal Aran, Laia; Sauras Colón, Esther; Ricomà Muntané, Roser; Ballester-Ferrando, D.; Rascón Hernán, C.; Botigué, Teresa; Lavedán, Ana; González Osorio, L.; Osorio Spuler, X.; Burjalés, D. (MDPI, 2021-03-15)
      In addition to complying with strict academic standards, nursing students must acquire relevant knowledge and skills, and learn how to carry themselves in different and often stressful professional settings. These obligations ...
    • Psychometric properties of the Catalan version of DS14 scale for assessing Type-D personality 

      Malas, Olga; Lucas, Ignacio; Lario, Jorge; Aluja Fabregat, Antón (Universitat de BarcelonaElsevier, 2018)
      This study was designed to check the psychometric properties of an online Catalan version of the Type D Personality Scale-14 (DS14). Participants were 600 subjects including university professors, service and administrative ...
    • Psychometric properties of the Catalan version of the Trait Emotional Intelligence (TEIQue): Comparison between Catalan and English data 

      Aluja Fabregat, Antón; Blanch Plana, Angel; Petrides, K. V. (Elsevier, 2016-05-18)
      The present study compared the psychometric properties of the Trait Emotional Intelligence Questionnaire (TEIQue) in Catalan and UK samples. The results showed similar means and standard deviations in the facets scoring ...
    • Psychometric properties of the SDM-Q-9 questionnaire for shared decision-making in multiple sclerosis: item response theory modelling and confirmatory factor analysis 

      Ballesteros, Javier; Moral, Ester; Brieva Ruiz, Luis; Ruiz-Beato, Elena; Prefasi, Daniel; Maurino, Jorge (BioMed Central, 2017)
      Background: Shared decision-making is a cornerstone of patient-centred care. The 9-item Shared Decision-Making Questionnaire (SDM-Q-9) is a brief self-assessment tool for measuring patients’ perceived level of involvement ...
    • Psychometric Properties of the SymptoMScreen Questionnaire in a Mild Disability Population of Patients with Relapsing–Remitting Multiple Sclerosis: Quantifying the Patient’s Perspective 

      Meca-Lallana, José E.; Maurino, Jorge; Hernández Pérez, Miguel A.; Sempere, Ángel P.; Brieva Ruiz, Luis; García-Arcelay, Elena; Terzaghi, María; Saposnik, Gustavo; Ballesteros, Javier (Springer, 2020)
      Crucial elements for achieving optimal long-term outcomes in multiple sclerosis (MS) are patient confidence and effective physician-patient communication. Patient-reported instruments may provide the means to fill the gap ...
    • Psychosocial work dimensions, personality, and body mass index: sex differences 

      Blanch Plana, Angel; Aluja Fabregat, Antón (Nofer Institute of Occupational Medicine, 2013)
      Objectives: The association between psychosocial work dimensions (i.e. demand and control) and obesity has been found to be inconclusive, indicating that individual differences factors might also contribute to explain the ...
    • Pterygium surgery by means of conjunctival autograft: long term follow-up 

      Huerva, Valentín; March, Anna; Martínez Alonso, Montserrat; Muniesa Royo, Ma. Jesús; Sanchez, Carmen (Conselho Brasileiro de Oftalmologia, 2012)
      PURPOSE: To demonstrate the long term of follow-up of the recurrence rate after conjunctival autograft for pterygium surgery. METHODS: A total of 112 patients operated for pterygium with conjunctival autografts and with ...
    • PVT1 long non-coding RNA in gastrointestinal cancer 

      Martínez Barriocanal, Águeda; Arango, Diego; Dopeso, Higinio (Frontiers Media, 2020)
      Whole genome and transcriptome sequencing technologies have led to the identification of many long non-coding RNAs (lncRNAs) and stimulated the research of their role in health and disease. LncRNAs participate in the ...