Now showing items 367-386 of 908

    • Fabry nephropathy: an evidence-based narrative review 

      Pino, María Dolores del; Andrés, Amado; Ávila Bernabéu, Ana; Juan-Rivera, Joaquín de; Fernández i Giráldez, Elvira; García Díaz, Juan de Dios; Hernández, Domingo; Luño, José; Martínez Fernández, Isabel; Paniagua, José; Torra, Roser; Torras Ambros, Joan; Vidau, Pedro; Torregrosa, Josep-Vicent (Karger Publishers Open Access, 2018)
      Fabry disease (FD) is a rare, X-linked disorder caused by mutations in the GLA gene encoding the enzyme α-galactosidase A. Complete or partial deficiency in this enzyme leads to intracellular accumulation of globotriaosylceramide ...
    • Factores asociados a la mortalidad global en los pacientes diagnosticados de enfermedad pulmonar obstructiva crónica 

      Godoy i García, Pere; Montserrat i Capdevila, Josep; Marsal Mora, Josep Ramon; Barbé Illa, Ferran (Elsevier España (Elsevier Doyma), 2015)
      Objetivo: Identificar los factores predictores de mortalidad en los pacientes con enfermedad pulmonar obstructiva crónica (EPOC). Diseño: Estudio de cohortes retrospectivas. Emplazamiento: Atención Primaria de Lleida, ...
    • Factores asociados con la mortalidad en pacientes traumáticos con puntuación de 3 en la escala de coma de Glasgow y midriasis bilateral arreactiva 

      Chico-Fernández, Mario; Barea-Mendoza, Jesús Abelardo; Servià Goixart, Lluís; Ormazabal-Zabala, Txoan; Quintana-Díaz, Manuel; González-Robledo, Javier; Iglesias-Santiago, Alberto; Sánchez-Arguiano, María Juncal; Pérez-Bárcena, Jon; Llompart-Pou, Juan Antonio (Sociedad Española de Medicina de Urgencias y Emergencias (SEMES), 2021-01-22)
      Objetivo. Comparar los pacientes traumáticos con una puntuación de 3 en la escala de coma de Glasgow (Glasgow Coma Scale, GCS) en función de la reactividad pupilar e investigar los factores asociados a la mortalidad ...
    • Factores de riesgo de hospitalización por gripe (H1N1) 2009 y efectividad de intervenciones farmacológicas y no farmacológicas en su prevención. Estudio de casos y controles 

      Domínguez García, Àngela; Alonso, Jordi; Astray, Jenaro; Baricot, Maretva; Cantón, Rafael; Castilla, Jesús; Castro, Ady; Delgado-Rodríguez, Miguel; Godoy i García, Pere; González-Candelas, Fernando; Martín, Vicente; Mayoral, José María; Quintana, José María; Perea, Emilio; Pumarola, Tomás; Soldevila, Núria; Tamames, Sonia; CIBERESP Cases and Controls in Pandemic Influenza Working Group (Ministerio de Sanidad y Consumo, 2011)
      Entre las medidas farmacológicas de posible utilidad para limitar el impacto de las pandemias gripales en la comunidad están los fármacos antivirales (inhibidores de la neuraminidasa) y las vacunas antigripales y ...
    • Factors Accounting for Obesity and Its Perception among the Adult Spanish Population: Data from 1,000 Computer-Assisted Telephone Interviews 

      Lecube Torelló, Albert; Sánchez Peña, Enric; Monereo, Susana; Medina-Gómez, Gema; Bellido, Diego; García-Almeida, José Manuel; Martínez de Icaya, Purificación; Malagón, Maria Mar; Goday, Albert; Tinahones, Francisco José (Karger Publishers, 2020)
      Objective: Our aim was to go deeper in the self-perception of weight and health status among the Spanish population, together with the connections of familiar relationships, physical activity practice, nutritional habits, ...
    • Factors associated to duration of hepatitis A outbreaks: implications for control 

      Torner Gràcia, Núria; Broner, Sonia; Martinez, Ana; Tortajada, Cecilia; Garcia de Olalla, Patricia; Barrabeig i Fabregat, Irene; Sala, Maria Rosa; Camps, Neus; Minguell, Sofia; Álvarez, Josep; Ferrús, Gloria; Torra, Roser; Godoy i García, Pere; Domínguez García, Àngela (Public Library of Science, 2012)
      Even though hepatitis A mass vaccination effectiveness is high, outbreaks continue to occur. The aim of this study was to investigate the association between duration and characteristics of hepatitis A outbreaks. Hepatitis ...
    • Factors associated with influenza vaccination of hospitalized elderly patients in Spain 

      Domínguez García, Àngela; Soldevila, Núria; Toledo, Diana; Godoy i García, Pere; Castilla, Jesús; Force, Lluís; Morales, María; Mayoral, José María; Egurrola, Mikel; Tamames, Sonia; Martín, Vicente; Astray, Jenaro (Public Library of Science, 2016)
      Vaccination of the elderly is an important factor in limiting the impact of influenza in the community. The aim of this study was to investigate the factors associated with influenza vaccination coverage in hospitalized ...
    • Factors Influencing Nurse Assistants' Job Satisfaction in Nursing Homes in Canada and Spain: A Comparison of Two Cross-Sectional Observational Studies 

      McGilton, Katherine S.; Stewart, Steven; Bethell, Jennifer; Chu, Charlene H.; Mateos, José Tomás; Pastells Peiró, Roland; Blanco Blanco, Joan; Rodriguez-Monforte, Miriam; Escrig-Pinol, Astrid; Gea Sánchez, Montserrat (SAGE Publications, 2020-12-22)
      Objectives: To access associations between job satisfaction and supervisory support as moderated by stress. Methods: For this cross-sectional study, data collected from 591 nursing assistants in 42 nursing homes in Canada ...
    • Factors influencing pathologic ankle-brachial index values along the chronic kidney disease spectrum: the Nefrona study 

      Arroyo, David; Betriu i Bars, M. Àngels; Valls, Joan; Gorriz, Jose L.; Pallares, Vicente; Abajo, María; Gracia, Marta; Valdivielso Revilla, José Manuel; Fernández i Giráldez, Elvira (Oxford University Press, 2016-04-01)
      BACKGROUND: The ankle-brachial index (ABI) is widely used to diagnose subclinical peripheral artery disease (PAD) in the general population, but data assessing its prevalence and related factors in different chronic kidney ...
    • Factors influencing the spread of pertussis in households: a prospective study, Catalonia and Navarre, Spain, 2012 to 2013 

      Godoy i García, Pere; García Cenoz, M.; Toledo, Diana; Carmona, Gloria; Caylà, Joan A.; Alsedà Graells, Miquel; Àlvarez, J.; Barrabeig i Fabregat, Irene; Camps, Neus; Plans, P.; Company, M.; Castilla, Jesús; Sala Farré, M.; Muñoz Almagro, C.; Rius, C.; Domínguez, A. (Eurosurveillance, 2016)
      We aimed to investigate transmission rates of pertussis in household contacts of cases and factors associated with transmission. A prospective epidemiological study was conducted in 2012 and 2013 to determine the incidence ...
    • Factors predicting cardiovascular events in chronic kidney disease patients. Role of subclinical atheromatosis extent assessed by vascular ultrasound 

      Valdivielso Revilla, José Manuel; Betriu i Bars, M. Àngels; Martínez Alonso, Montserrat; Arroyo, David; Bermúdez López, Marcelino; Fernández i Giráldez, Elvira (Public Library of Science, 2017)
      Patients with chronic kidney disease (CKD) have an increased incidence of cardiovascular events (CVE). The contribution of subclinical atheromatosis extent, including femoral arteries, to CVE in CKD patients has not been ...
    • FAIM-L Is an IAP-Binding Protein That Inhibits XIAP Ubiquitinylation and Protects from Fas-Induced Apoptosis 

      Moubarak, Rana S.; Planells Ferrer, Laura; Urresti, Jorge; Reix, Stéphanie; Segura Ginard, Miguel Francisco; Carriba, Paulina; Marqués Fernàndez, Fernando; Solé Serra, Carme; Llecha Cano, Núria; López Soriano, Joaquin; Sanchis, Daniel; Yuste Mateos, Víctor J. (Víctor José); Comella i Carnicé, Joan Xavier (Society for Neuroscience, 2013)
      The neuronal long isoform of Fas Apoptotic Inhibitory Molecule (FAIM-L) protects from death receptor (DR)-induced apoptosis, yet its mechanism of protection remains unknown. Here, we show that FAIM-L protects rat neuronal ...
    • FAK inhibition induces glioblastoma cell senescence-like state through p62 and p27 

      Alza, Lía; Nàger Grifo, Mireia; Visa Pretel, Anna; Cantí Nicolás, Carles; Herreros Danés, Judit (MDPI, 2020-04-27)
      Focal adhesion kinase (FAK) is a central component of focal adhesions that regulate cancer cell proliferation and migration. Here, we studied the effects of FAK inhibition in glioblastoma (GBM), a fast growing brain tumor ...
    • La farmacologia de la coagulació plasmàtica per via oral al segle XXI 

      Boix Torras, Jacint; Ribas i Fortuny, Judit (Col·legi Oficial de Metges de Lleida, 2012)
    • Fear of falling in community-dwelling older adults: A cause of falls, a consequence, or both? 

      Lavedán, Ana; Viladrosa, Maria; Jürschik, Pilar; Botigué, Teresa; Nuin Orrio, Carmen; Masot, Olga; Lavedán, Raquel (Public Library of Science, 2018-03-29)
      Background: Despite the number of studies that have tried to demonstrate that there is an association between previous falls and the fear of falling, the relationship between these two variables remains a matter of ...
    • Feasibility and acceptability of personalised breast cancer screening (DECIDO study): protocol of a single-arm proof-of-concept trial 

      Pons Rodríguez, Anna; Forné Izquierdo, Carles; Vilaplana Mayoral, Jordi; Cruz Esteve, María Inés; Sánchez-López, Isabel; Reñé Reñé, Mercè; Cazorla, Cristina; Hernández Andreu, Marta; Galindo Ortego, Gisela; Llorens Gabandé, Montserrat; Laza-Vásquez, Celmira; Balaguer Llaquet, Pau; Martínez Alonso, Montserrat; Rué i Monné, Montserrat (BMJ Publishing Group, 2020-12-23)
      Introduction Personalised cancer screening aims to improve benefits, reduce harms and being more cost-effective than age-based screening. The objective of the DECIDO study is to assess the acceptability and feasibility of ...
    • First-line bevacizumab and capecitabine-oxaliplatin in elderly patients with mCRC: GEMCAD phase II BECOX study 

      Feliu, Jaume; Salud Salvia, Maria Antonieta; Safont, M. J.; García-Girón, C.; Aparicio, Jorge; Serra, O.; Vera, R.; Casado, Enrique; Jorge, Monica; Escudero, P.; Bosch, Carlos; Bohn, Uriel; Pérez-Carrión, Ramon; Carmona, Alberto; Martínez-Marín, V.; Maurel, Joan (Cancer Research UK, 2014)
      Background: Subgroup analyses of clinical studies suggest that bevacizumab plus XELOX is effective and tolerable in elderly patients with metastatic colorectal cancer (mCRC). The prospective BECOX study examined the ...
    • FISH analysis of PTEN in endometrial carcinoma. Comparison with SNP arrays and MLPA 

      Maiques Carlos, Oscar; Cuevas, Dolors; García Dios, Diego Andrés; Coenegrachts, Lieve; Santacana, Maria; Velasco, Ana; Romero, Marta; Gatius Calderó, Sònia; Lambrechts, Diether; Müller, Sven; Pedersen, Hans Christian; Dolcet Roca, Xavier; Amant, Frederic; Matias-Guiu, Xavier (Wiley, 2014)
      Aims: To check the usefulness of a standardized protocol of PTEN FISH in 31 endometrial carcinomas (ECs) in comparison with SNP array (SNPA), multiplex ligation-dependent probe amplification (MLPA), and immunohistochemistry. ...
    • FLRT2 and FLRT3 act as repulsive guidance cues for Unc5-positive neurons 

      Yamagishi, Satoru; Hampel, Falko; Hata, Katsuhiko; Toro, Daniel del; Schwark, Manuela; Kvachnina, Elena; Bastmeyer, Martin; Yamashita, Toshihide; Tarabykin, Victor; Klein, Rüdiger; Egea Navarro, Joaquim (EMBO Press, 2011)
      Netrin-1 induces repulsive axon guidance by binding to the mammalian Unc5 receptor family (Unc5A–Unc5D). Mouse genetic analysis of selected members of the Unc5 family, however, revealed essential functions independent of ...
    • FLRT3 Is a Robo1-Interacting Protein that Determines Netrin-1 Attraction in Developing Axons 

      Leyva-Díaz, Eduardo; Toro, Daniel del; Menal Castellote, Maria José; Cambray Carner, Serafí; Susín, Rafael; Tessier-Lavigne, Marc; Klein, Rüdiger; Egea Navarro, Joaquim; López-Bendito, Guillermina (Elsevier, 2014)
      Background: Guidance molecules are normally presented to cells in an overlapping fashion; however, little is known about how their signals are integrated to control the formation of neural circuits. In the thalamocortical ...