Now showing items 1-20 of 474

    • The humanitarian impact of plant biotechnology: recent breakthroughs vs bottlenecks for adoption 

      Farré Martinez, Gemma; Ramessar, Koreen; Twyman, Richard M.; Capell Capell, Teresa; Christou, Paul (Elsevier, 2010)
      The deployment of genetically engineered (GE) crops in developing countries is regarded by some as a sinister manifestation of ‘big business’ in science. What is often overlooked, and sometimes even deliberately ignored ...
    • Critical evaluation of strategies for mineral fortification of staple food crops 

      Gómez Galera, Sonia; Rojas, Eduard; Sudhakar, Duraialagaraja; Zhu, Changfu; Pelacho Aja, Ana Mª; Capell Capell, Teresa; Christou, Paul (Springer Verlag, 2010)
      Staple food crops, in particular cereal grains, are poor sources of key mineral nutrients. As a result, the world’s poorest people, generally those subsisting on a monotonous cereal diet, are also those most vulnerable ...
    • First Report on Mould and Mycotoxin Contamination of Pistachios Sampled in Algeria 

      Fernane, F.; Sanchís Almenar, Vicente; Marín Sillué, Sònia; Ramos Girona, Antonio J. (Springer, 2010)
      Mycotoxin contamination of pistachios represents a serious food safety hazard. The aim of this study was to evaluate fungal contamination and aflatoxin (AF) and ochratoxin A (OTA) occurrence in pistachio sampled in Algeria ...
    • Functional characterization of the Gentiana lutea zeaxanthin epoxidase (GlZEP) promoter in transgenic tomato plants 

      Yang, Qingjie; Yuan, Dawei; Shi, Lianxuan; Capell Capell, Teresa; Bai, Chao; Wen, Nuan; Lu, Xiaodan; Sandmann, Gerhard; Christou, Paul; Zhu, Changfu (Springer Verlag, 2010)
      The accumulation of carotenoids in plants depends critically on the spatiotemporal expression profiles of the genes encoding enzymes in the carotenogenic pathway. We cloned and characterized the Gentiana lutea zeaxanthin ...
    • Promoter diversity in multigene transformation 

      Peremartí, Ariadna; Twyman, Richard M.; Gómez Galera, Sonia; Naqvi, Shaista; Farré Martinez, Gemma; Sabalza Gallués, Maite; Miralpeix i Anglada, Bruna; Dashevskaya, Svetlana; Yuan, Dawei; Ramessar, Koreen; Christou, Paul; Zhu, Changfu; Bassie Rene, Ludovic; Capell Capell, Teresa (Springer Verlag, 2010)
      Multigene transformation (MGT) is becoming routine in plant biotechnology as researchers seek to generate more complex and ambitious phenotypes in transgenic plants. Every nuclear transgene requires its own promoter, ...
    • When more is better: multigene engineering in plants 

      Naqvi, Shaista; Farré Martinez, Gemma; Sanahuja Solsona, Georgina; Capell Capell, Teresa; Zhu, Changfu; Christou, Paul (Elsevier, 2010)
      The genomics revolution has taught us that a great deal of information can be derived from studying many genes or proteins at the same time. We are beginning to see this approach blossoming in applied research. Instead ...
    • Cloning and functional characterization of the maize carotenoid isomerase and β-carotene hydroxylase genes and their regulation during endosperm maturation 

      Li, Qunrui; Farré Martinez, Gemma; Naqvi, Shaista; Breitenbach, Jürgen; Sanahuja Solsona, Georgina; Bai, Chao; Sandmann, Gerhard; Capell Capell, Teresa; Christou, Paul; Zhu, Changfu (Springer Netherlands, 2010)
      In order to gain further insight into the partly-characterized carotenoid biosynthetic pathway in corn (Zea mays L.), we cloned cDNAs encoding the enzymes carotenoid isomerase (CRTISO) and β-carotene hydroxylase (BCH) using ...
    • Travel advice on the road to carotenoids in plants 

      Farré Martinez, Gemma; Sanahuja Solsona, Georgina; Naqvi, Shaista; Bai, Chao; Capell Capell, Teresa; Zhu, Changfu; Christou, Paul (Elsevier, 2010)
      The carotenoids are a major class of organic pigments produced in plants and microbes. They fulfill many essential physiological and developmental processes in plants, and also have important roles in animal health and ...
    • The regulation of carotenoid pigmentation in flowers 

      Zhu, Changfu; Bai, Chao; Sanahuja Solsona, Georgina; Yuan, Dawei; Farré Martinez, Gemma; Naqvi, Shaista; Shi, Lianxuan; Capell Capell, Teresa; Christou, Paul (Elsevier, 2010)
      Carotenoids fulfill many processes that are essential for normal growth and development in plants, but they are also responsible for the breathtaking variety of red-to-yellow colors we see in flowers and fruits. Although ...
    • Differential expression of LIM-Homeodomain factors in Cajal-Retzius cells of primates, rodents, and birds 

      Abellán Ródenas, Antonio; Menuet, Arnaud; Dehay, Colette; Medina Hernández, Loreta Mª; Rétaux, Sylvie (Oxford Journals, 2010)
      Reelin-expressing Cajal-Retzius (CR) cells are among the earliest generated cells in the mammalian cerebral cortex and are believed to be crucial for both the development and the evolution of a laminated pattern in the ...
    • Valproic acid induces antioxidant effects in X-linked adrenoleukodystrophy 

      Fourcade, Stéphane; Ruiz, Montserrat; Guilera, Cristina; Hahnen, Eric; Brichta, Lars; Naudí i Farré, Alba; Portero Otín, Manuel; Dacremont, Georges; Cartier, Nathalie; Wanders, Ronald; Kemp, Stephan; Mandel, Jean Louis; Wirth, Brunhilde; Pamplona Gras, Reinald; Aubourg, Patrick; Pujol, Aurora (Oxford University Press, 2010)
      X-linked adrenoleukodystrophy (X-ALD) is a fatal, axonal demyelinating, neurometabolic disease. It results from the functional loss of a member of the peroxisomal ATP-binding cassette transporter subfamily D (ABCD1), ...
    • Bacillus thuringiensis: a century of research, development and commercial applications 

      Sanahuja Solsona, Georgina; Banakar, Raviraj; Twyman, Richard M.; Capell Capell, Teresa; Christou, Paul (Wiley, 2011)
      Bacillus thuringiensis (Bt) is a soil bacterium that forms spores during the stationary phase of its growth cycle. The spores contain crystals, predominantly comprising one or more Cry and/or Cyt proteins (also known as ...
    • T-Coffee: a web server for the multiple sequence alignment of protein and RNA sequences using structural information and homology extension 

      Di Tommaso, Paolo; Moretti, Sebastien; Xenarios, Ioannis; Orobitg Cortada, Miquel; Montañola Lacort, Alberto (Oxford University Press, 2011)
      This article introduces a new interface for T-Coffee, a consistency-based multiple sequence alignment program. This interface provides an easy and intuitive access to the most popular functionality of the package. These ...
    • Mould growth and mycotoxin production as affected by Equisetum arvense and Stevia rebaudiana extracts 

      García, Daiana; García Cela, Esther; Ramos Girona, Antonio J.; Sanchís Almenar, Vicente; Marín Sillué, Sònia (Elsevier, 2011)
      Cereals are very important for human and animal diet. However, agricultural products can be contaminated by moulds and their mycotoxins. On the other hand, natural plant products with antimicrobial properties could be a ...
    • Climate at the onset of western Mediterranean agriculture expansion: Evidence from stable isotopes of sub-fossil oak tree rings in Spain 

      Aguilera, Mònica; Ferrio Díaz, Juan Pedro; Araus Ortega, José Luis; Tarrús, J.; Voltas Velasco, Jordi (Elsevier, 2011)
      Climate conditions during the early Holocene may have contributed to the spread of Old World agriculture from its area of birth, in the Fertile Crescent (Near East), west through the Mediterranean Basin. Reconstructing the ...
    • Simultaneous expression of Arabidopsis ρ-hydroxyphenylpyruvate dioxygenase and MPBQ methyltransferase in transgenic corn kernels triples the tocopherol content 

      Naqvi, Shaista; Farré Martinez, Gemma; Zhu, Changfu; Sandmann, Gerhard; Capell Capell, Teresa; Christou, Paul (Springer Verlag, 2011)
      The quantity and composition of tocopherols (compounds with vitamin E activity) vary widely among different plant species reflecting the expression, activity and substrate specificity of enzymes in the corresponding ...
    • High-value products from transgenic maize 

      Naqvi, Shaista; Ramessar, Koreen; Farré Martinez, Gemma; Sabalza Gallués, Maite; Miralpeix i Anglada, Bruna; Twyman, Richard M.; Capell Capell, Teresa; Zhu, Changfu; Christou, Paul (Elsevier, 2011)
      Maize (also known as corn) is a domesticated cereal grain that has been grown as food and animal feed for tens of thousands of years. It is currently the most widely grown crop in the world, and is used not only for food/feed ...
    • Nutritious crops producing multiple carotenoids – a metabolic balancing act 

      Farré Martinez, Gemma; Bai, Chao; Twyman, Richard M.; Capell Capell, Teresa; Christou, Paul; Zhu, Changfu (Elsevier, 2011)
      Plants and microbes produce multiple carotenoid pigments with important nutritional roles in animals. By unraveling the basis of carotenoid biosynthesis it has become possible to modulate the key metabolic steps in plants ...
    • Modelling the effect of temperature and water activity of Aspergillus flavus isolates from corn 

      Astoreca, A.; Vaamonde, G.; Dalcero, A.; Ramos Girona, Antonio J.; Marín Sillué, Sònia (Elsevier, 2011)
      The aim of this study was to model the effects of temperature (10–40 °C) and aw (0.80–0.98), in two media (Czapek yeast agar: CYA; corn extract medium: CEM) on the growth rates and growth boundaries (growth–no growth ...
    • Synergistic metabolism in hybrid corn indicates bottlenecks in the carotenoid pathway and leads to the accumulation of extraordinary levels of the nutritionally important carotenoid zeaxanthin 

      Naqvi, Shaista; Zhu, Changfu; Farré Martinez, Gemma; Sandmann, Gerhard; Capell Capell, Teresa; Christou, Paul (Wiley, 2011)
      Lutein and zeaxanthin cannot be synthesized de novo in humans, and althoughlutein is abundant in fruit and vegetables, good dietary sources of zeaxanthin arescarce. Certain corn varieties provide adequate amounts because ...