Ara es mostren els elements 1-20 de 590

    • Valproic acid induces antioxidant effects in X-linked adrenoleukodystrophy 

      Fourcade, Stéphane; Ruiz, Montserrat; Guilera, Cristina; Hahnen, Eric; Brichta, Lars; Naudí i Farré, Alba; Portero Otín, Manuel; Dacremont, Georges; Cartier, Nathalie; Wanders, Ronald; Kemp, Stephan; Mandel, Jean Louis; Wirth, Brunhilde; Pamplona Gras, Reinald; Aubourg, Patrick; Pujol, Aurora (Oxford University Press, 2010)
      X-linked adrenoleukodystrophy (X-ALD) is a fatal, axonal demyelinating, neurometabolic disease. It results from the functional loss of a member of the peroxisomal ATP-binding cassette transporter subfamily D (ABCD1), ...
    • Cloning and functional characterization of the maize carotenoid isomerase and β-carotene hydroxylase genes and their regulation during endosperm maturation 

      Li, Qunrui; Farré Martinez, Gemma; Naqvi, Shaista; Breitenbach, Jürgen; Sanahuja Solsona, Georgina; Bai, Chao; Sandmann, Gerhard; Capell Capell, Teresa; Christou, Paul; Zhu, Changfu (Springer Netherlands, 2010)
      In order to gain further insight into the partly-characterized carotenoid biosynthetic pathway in corn (Zea mays L.), we cloned cDNAs encoding the enzymes carotenoid isomerase (CRTISO) and β-carotene hydroxylase (BCH) using ...
    • The regulation of carotenoid pigmentation in flowers 

      Zhu, Changfu; Bai, Chao; Sanahuja Solsona, Georgina; Yuan, Dawei; Farré Martinez, Gemma; Naqvi, Shaista; Shi, Lianxuan; Capell Capell, Teresa; Christou, Paul (Elsevier, 2010)
      Carotenoids fulfill many processes that are essential for normal growth and development in plants, but they are also responsible for the breathtaking variety of red-to-yellow colors we see in flowers and fruits. Although ...
    • When more is better: multigene engineering in plants 

      Naqvi, Shaista; Farré Martinez, Gemma; Sanahuja Solsona, Georgina; Capell Capell, Teresa; Zhu, Changfu; Christou, Paul (Elsevier, 2010)
      The genomics revolution has taught us that a great deal of information can be derived from studying many genes or proteins at the same time. We are beginning to see this approach blossoming in applied research. Instead ...
    • Travel advice on the road to carotenoids in plants 

      Farré Martinez, Gemma; Sanahuja Solsona, Georgina; Naqvi, Shaista; Bai, Chao; Capell Capell, Teresa; Zhu, Changfu; Christou, Paul (Elsevier, 2010)
      The carotenoids are a major class of organic pigments produced in plants and microbes. They fulfill many essential physiological and developmental processes in plants, and also have important roles in animal health and ...
    • Differential expression of LIM-Homeodomain factors in Cajal-Retzius cells of primates, rodents, and birds 

      Abellán Ródenas, Antonio; Menuet, Arnaud; Dehay, Colette; Medina Hernández, Loreta Mª; Rétaux, Sylvie (Oxford Journals, 2010)
      Reelin-expressing Cajal-Retzius (CR) cells are among the earliest generated cells in the mammalian cerebral cortex and are believed to be crucial for both the development and the evolution of a laminated pattern in the ...
    • The humanitarian impact of plant biotechnology: recent breakthroughs vs bottlenecks for adoption 

      Farré Martinez, Gemma; Ramessar, Koreen; Twyman, Richard M.; Capell Capell, Teresa; Christou, Paul (Elsevier, 2010)
      The deployment of genetically engineered (GE) crops in developing countries is regarded by some as a sinister manifestation of ‘big business’ in science. What is often overlooked, and sometimes even deliberately ignored ...
    • Functional characterization of the Gentiana lutea zeaxanthin epoxidase (GlZEP) promoter in transgenic tomato plants 

      Yang, Qingjie; Yuan, Dawei; Shi, Lianxuan; Capell Capell, Teresa; Bai, Chao; Wen, Nuan; Lu, Xiaodan; Sandmann, Gerhard; Christou, Paul; Zhu, Changfu (Springer Verlag, 2010)
      The accumulation of carotenoids in plants depends critically on the spatiotemporal expression profiles of the genes encoding enzymes in the carotenogenic pathway. We cloned and characterized the Gentiana lutea zeaxanthin ...
    • Critical evaluation of strategies for mineral fortification of staple food crops 

      Gómez Galera, Sonia; Rojas, Eduard; Sudhakar, Duraialagaraja; Zhu, Changfu; Pelacho Aja, Ana Mª; Capell Capell, Teresa; Christou, Paul (Springer Verlag, 2010)
      Staple food crops, in particular cereal grains, are poor sources of key mineral nutrients. As a result, the world’s poorest people, generally those subsisting on a monotonous cereal diet, are also those most vulnerable ...
    • First Report on Mould and Mycotoxin Contamination of Pistachios Sampled in Algeria 

      Fernane, F.; Sanchís Almenar, Vicente; Marín Sillué, Sònia; Ramos Girona, Antonio J. (Springer, 2010)
      Mycotoxin contamination of pistachios represents a serious food safety hazard. The aim of this study was to evaluate fungal contamination and aflatoxin (AF) and ochratoxin A (OTA) occurrence in pistachio sampled in Algeria ...
    • Promoter diversity in multigene transformation 

      Peremartí, Ariadna; Twyman, Richard M.; Gómez Galera, Sonia; Naqvi, Shaista; Farré Martinez, Gemma; Sabalza Gallués, Maite; Miralpeix i Anglada, Bruna; Dashevskaya, Svetlana; Yuan, Dawei; Ramessar, Koreen; Christou, Paul; Zhu, Changfu; Bassie Rene, Ludovic; Capell Capell, Teresa (Springer Verlag, 2010)
      Multigene transformation (MGT) is becoming routine in plant biotechnology as researchers seek to generate more complex and ambitious phenotypes in transgenic plants. Every nuclear transgene requires its own promoter, ...
    • Bacillus thuringiensis: a century of research, development and commercial applications 

      Sanahuja Solsona, Georgina; Banakar, Raviraj; Twyman, Richard M.; Capell Capell, Teresa; Christou, Paul (Wiley, 2011)
      Bacillus thuringiensis (Bt) is a soil bacterium that forms spores during the stationary phase of its growth cycle. The spores contain crystals, predominantly comprising one or more Cry and/or Cyt proteins (also known as ...
    • T-Coffee: a web server for the multiple sequence alignment of protein and RNA sequences using structural information and homology extension 

      Di Tommaso, Paolo; Moretti, Sebastien; Xenarios, Ioannis; Orobitg Cortada, Miquel; Montañola Lacort, Alberto (Oxford University Press, 2011)
      This article introduces a new interface for T-Coffee, a consistency-based multiple sequence alignment program. This interface provides an easy and intuitive access to the most popular functionality of the package. These ...
    • A user-friendly web portal for T-Coffee on supercomputers 

      Rius Torrentó, Josep Maria; Cores Prado, Fernando; Solsona Tehàs, Francesc; Hemert, Jano van; Koetsier, Jos; Notredame, Cedric (BioMed Central, 2011)
      Background: Parallel T-Coffee (PTC) was the first parallel implementation of the T-Coffee multiple sequence alignment tool. It is based on MPI and RMA mechanisms. Its purpose is to reduce the execution time of the large-scale ...
    • Boolean lexicographic optimization: algorithms & applications 

      Marques-Silva, Joao; Argelich Romà, Josep; Graça, Ana; Lynce, Inês (Springer Verlag, 2011)
      Multi-Objective Combinatorial Optimization (MOCO) problems find a wide range of practical application problems, some of which involving Boolean variables and constraints. This paper develops and evaluates algorithms for ...
    • Modelling the effect of temperature and water activity of Aspergillus flavus isolates from corn 

      Astoreca, A.; Vaamonde, G.; Dalcero, A.; Ramos Girona, Antonio J.; Marín Sillué, Sònia (Elsevier, 2011)
      The aim of this study was to model the effects of temperature (10–40 °C) and aw (0.80–0.98), in two media (Czapek yeast agar: CYA; corn extract medium: CEM) on the growth rates and growth boundaries (growth–no growth ...
    • Climate at the onset of western Mediterranean agriculture expansion: Evidence from stable isotopes of sub-fossil oak tree rings in Spain 

      Aguilera, Mònica; Ferrio Díaz, Juan Pedro; Araus Ortega, José Luis; Tarrús, J.; Voltas Velasco, Jordi (Elsevier, 2011)
      Climate conditions during the early Holocene may have contributed to the spread of Old World agriculture from its area of birth, in the Fertile Crescent (Near East), west through the Mediterranean Basin. Reconstructing the ...
    • Nutritionally enhanced crops and food security: scientific achievements versus political expediency 

      Farré Martinez, Gemma; Twyman, Richard M.; Zhu, Changfu; Capell Capell, Teresa; Christou, Paul (Elsevier, 2011)
      Genetic engineering (GE) is one of a raft of strategies that can be used to tackle malnutrition. Recent scientific advances have shown that multiple deficiencies can be tackled simultaneously using engineered plant varieties ...
    • Computation of current distribution in YBCO tapes with defects obtained from hall magnetic mapping by inverse problem solution 

      Carrera i Vilanova, Miquel; Amorós, J.; Granados, X.; Maynou, R.; Puig, Teresa; Obradors, X. (IEEE, 2011)
      The development of superconducting devices based on long-length HTS tapes often requires of these tapes high homogeneity along its length as well as across its width. This implies the absence of significant local defects. ...
    • Oxidative damage compromises energy metabolism in the axonal degeneration mouse model of X-Adrenoleukodystrophy 

      Fourcade, Stéphane; Schlüter, Agatha; López Erauskin, Jone; Guilera, Cristina; Jové Font, Mariona; Naudí i Farré, Alba; García Arumí, Elena; Andreu, Antoni L.; Starkov, Anatoly A.; Pamplona Gras, Reinald; Ferrer, Isidre; Portero Otín, Manuel; Pujol, Aurora (Mary Ann Liebert, Inc., 2011)
      Aims: Chronic metabolic impairment and oxidative stress are associated with the pathogenesis of axonal dysfunction in a growing number of neurodegenerative conditions. To investigate the intertwining of both noxious factors, ...