Now showing items 59-78 of 469

    • C-reactive protein and other predictors of poor outcome in patients hospitalized with exacerbations of chronic obstructive pulmonary disease 

      Ruiz González, Agustín; Lacasta García, José Daniel; Ibarz Escuer, Mercedes; Martínez Alonso, Montserrat; Falguera i Sacrest, Miquel; Porcel Pérez, José Manuel (Wiley, 2008)
      Background and objective: CRP is elevated in patients with acute exacerbations of COPD (AECOPD), but there is little information on whether this biomarker can help to identify adverse short-term clinical outcomes. Methods: ...
    • Calcium channel expression and applicability as targeted therapies in melanoma 

      Macià Armengol, Anna; Herreros Danés, Judit; Martí Laborda, Rosa Ma.; Cantí Nicolás, Carles (Hindawi Publishing Corporation, 2015)
      The remodeling of Ca2+ signaling is a common finding in cancer pathophysiology serving the purpose of facilitating proliferation, migration, or survival of cancer cells subjected to stressful conditions. One particular ...
    • Calcium phosphate product is associated with subclinical carotid atherosclerosis in type 2 diabetes 

      Ramírez-Morros, Anna; Granado Casas, Minerva; Alcubierre Calvo, Núria; Martínez Alonso, Montserrat; Real, Jordi; Castelblanco Echavarría, Esmeralda; Esquerda, Aureli; Cao, Gonzalo; Rubinat, Esther; Hernández García, Marta; Alonso, Núria; Fernández i Giráldez, Elvira; Mauricio Puente, Dídac (Hindawi Publishing Corporation, 2017)
      Aims. To assess whether circulating 25-hydroxyvitamin D3 (25OHD) and mineral metabolism-related factors (serum phosphate, calcium, and parathormone) are associated with subclinical carotid atherosclerosis (SCA), defined ...
    • Capecitabine and bevacizumab as first-line treatment in elderly patients with metastatic colorectal cancer 

      Feliu, Jaime; Safont, M. J.; Salud Salvia, Maria Antonieta; Losa, F.; García-Girón, C.; Bosch, Carlos; Escudero, P.; López, R.; Madroñal, C.; Bolaños, M.; Gil, M.; Llombart, A.; Castro-Carpeño, J.; González-Barón, M. (Nature Publishing Group; Cancer Research UK, 2010)
      BACKGROUND: The efficacy and safety of capecitabine and bevacizumab in elderly patients with metastatic colorectal cancer (mCRC) considered unsuitable for receiving first-line chemotherapy with an irinotecan or oxaliplatin-based ...
    • Capecitabine and irinotecan with bevacizumab 2-weekly for metastatic colorectal cancer: the phase II AVAXIRI study 

      Garcia-Alfonso, Pilar; Chaves, Manuel; Muñoz, Andrés; Salud Salvia, Maria Antonieta; García-Gonzalez, Maria; Grávalos, Cristina; Massuti, Bartomeu; González-Flores, Encarna; Queralt, Bernardo; López-Ladrón, Amelia; Losa, F.; Gómez, Maria Jose; Oltra, Amparo; Aranda, Enrique (BioMed Central, 2015)
      Background: The optimal sequence of chemotherapeutic agents is not firmly established for the treatment of metastatic colorectal cancer (mCRC). This phase II multi-centre study investigated the efficacy and tolerability ...
    • Cardiac troponin values in patients with acute coronary syndrome and sleep apnea: a pilot study 

      Sánchez de la Torre, Alicia; Soler, Xavier; Barbé Illa, Ferran; Florés, Marina; Maisel, Alan; Malhotra, Atul; Rué i Monné, Montserrat; Bertran, Sandra; Aldomá, Albina; Worner, Fernando; Valls Marsal, Joan; Lee, Chi-Hang; Turino, Cecilia; Galera, Estefanía; Batlle Garcia, Jordi de; Sánchez de la Torre, Manuel (Elsevier, 2018)
      Background: An analysis of cardiac injury markers in patients with OSA who sustain an episode of acute coronary syndrome (ACS) may contribute to a better understanding of the interactions and impact of OSA in subjects with ...
    • Cardiovascular risk factors and the impact on prognosis in patients with chronic kidney disease secondary to autosomal dominant polycystic kidney disease 

      Gorriz, Jose L.; Arroyo, David; D’Marco, Luis; Torra, Roser; Tomás, Patricia; Puchades, María Jesús; Panizo, Nayara; Pantoja, Jonay; Montomoli, Marco; Llisterri, José Luis; Pallares Carratalá, Vicente; Valdivielso Revilla, José Manuel (BMC, 2021)
      Background: Autosomal dominant polycystic kidney disease (ADPKD) is the most frequent hereditary renal disease. There is an increased rate of cardiovascular disease (CVD) in ADPKD. In this study, we evaluate the prevalence ...
    • Cardiovascular Risk Factors in Atrial Fibrillation Associated with Ischaemic Heart Disease 

      Pérez Mur, Jesús; Gutiérrez, Eric; Valls, Joan; Fornés, Sònia; Yuguero Torres, Oriol (Science Repository OÜ, 2020)
      Objective: To describe cardiovascular risk factors in Atrial Fibrillation (AF) in relation with ischaemic diseases in an emergency service. Methodology: Cross-sectional study of patients with AF attended in the (ES) of ...
    • Carotid ultrasound for the early diagnosis of atherosclerosis in chronic kidney disease 

      Fernández i Giráldez, Elvira; Betriu i Bars, M. Àngels (Sociedad Española de Nefrología, 2012)
      Atherothrombotic disease (ATD) is a progressive disorder and its most common clinical manifestations, acute myocardial infarction and stroke, are responsible for the highest morbidity and mortality rates in the Western ...
    • Caspase 8/10 are not mediating apoptosis in neuroblastoma cells treated with CDK inhibitory drugs 

      Ribas i Fortuny, Judit; Gómez Arbonés, Javier; Boix Torras, Jacint (Elsevier, 2005)
      Olomoucine and Roscovitine are pharmacological inhibitors of cyclin-dependent kinases (CDK) displaying a promising profile as anticancer agents. Both compounds are effective inductors of apoptosis in a human neuroblastoma ...
    • Central sleep apnoea is related to the severity and short-term prognosis of acute coronary syndrome 

      Florés, Marina; Batlle Garcia, Jordi de; Sánchez de la Torre, Alicia; Sánchez de la Torre, Manuel; Aldomá, Albina; Worner, Fernando; Galera, Estefanía; Seminario, Asunción; Torres, Gerard; Dalmases, Mireia; Montserrat i Capdevila, Josep; Garmendia, Onintza; Barbé Illa, Ferran (Public Library of Science, 2016)
      Objective To evaluate the relation of central sleep apnoea (CSA) to the severity and short-term prognosis of patients who experience acute coronary syndrome (ACS). Methods Observational study with cross-sectional and ...
    • Characterisation of the inflammatory response triggered by topical ingenol mebutate 0.05% gel in basal cell carcinoma 

      García de la Fuente, María Reyes; Santacana Espasa, Maria; Verdaguer Autonell, Joan; Vilardell, Felip; Garí Marsol, Eloi; Casanova i Seuma, Josep M. (Josep Manel) (Wiley; Australasian College of Dermatologists, 2020-01-16)
      Background/Objective Ingenol mebutate gel is approved for actinic keratosis field therapy, but little has been published as a treatment of basal cell carcinoma (BCC). Our objective is to characterise the histopathological ...
    • Characteristics of atheromatosis in the prediabetes stage: a cross-sectional investigation of the Ilervas project 

      Sánchez Peña, Enric; Betriu i Bars, M. Àngels; López Cano, Carolina; Hernández García, Marta; Fernández i Giráldez, Elvira; Purroy Garcia, Francisco; Bermúdez López, Marcelino; Farràs-Sallés, Cristina; Barril, Silvia; Pamplona Gras, Reinald; Rius, Ferran; Hernández, Cristina; Simó, Rafael; Lecube Torelló, Albert (BioMed Central, 2019-11-15)
      BACKGROUND: Prediabetes has recently been associated with subclinical atheromatous disease in the middle-aged population. Our aim was to characterize atheromatous plaque burden by the number of affected territories and the ...
    • Characterization and prognostic implication of 17 chromosome abnormalities in myelodysplastic syndrome 

      Sánchez Castro, Judit; Marco Betés, Victor; Gómez Arbonés, Javier; Arenillas, Leonor; Valcarcel, David; Vallespí, Teresa; Costa, Dolors; Nomdedeu, Benet; Jimenez, María José; Granada, Isabel; Grau, Javier; Ardanaz, María T.; Serna, Javier de la; Carbonell, Félix; Cervera, José; Sierra, Adriana; Luño, Elisa; Cervero, Carlos J.; Falantes, José; Calasanz, María J.; González-Porrás, José R.; Bailén, Alicia; Amigo, M. Luz; Sanz, Guillermo; Solé, Francesc (Elsevier, 2013)
      The prognosis of chromosome 17 (chr17) abnormalities in patients with primary myelodysplastic syndrome (MDS) remains unclear. The revised International Prognostic Scoring System (IPSS-R) includes these abnormalities within ...
    • Characterization of sleep breathing pattern in patients with type 2 diabetes: sweet sleep study 

      Lecube Torelló, Albert; Sampol, Gabriel; Hernández, Cristina; Romero, Odile; Ciudin, Andreea; Simó, Rafael (Public Library of Science, 2015)
      Background: Although sleep apnea-hypopnea syndrome (SAHS) is highly prevalent in patients with type 2 diabetes (T2D), it is unknown whether or not subjects with and without T2D share the same sleep breathing pattern. ...
    • Characterization of the CPAP-treated patient population in Catalonia 

      Turino, Cecilia; Bertran, Sandra; Gavaldá, Ricard; Teixidó Torrelles, Ivan; Woehrle, Holger; Rué i Monné, Montserrat; Solsona Tehàs, Francesc; Escarrabill, Joan; Colls, Cristina; García-Altés, Anna; Batlle Garcia, Jordi de; Sánchez de la Torre, Manuel; Barbé Illa, Ferran (Public Library of Science, 2017)
      There are different phenotypes of obstructive sleep apnoea (OSA), many of which have not been characterised. Identification of these different phenotypes is important in defining prognosis and guiding the therapeutic ...
    • Characterizing the Invasive Tumor Front of Aggressive Uterine Adenocarcinoma and Leiomyosarcoma 

      Sanegre, Sabina; Eritja Sánchez, Núria; De Andrea, Carlos; Diaz-Martin, Juan; Diaz-Lagares, Ángel; Jácome, María Amalia; Salguero-Aranda, Carmen; García Ros, David; Davidson, Ben; Lopez, Rafel; Melero, Ignacio; Navarro, Samuel; Ramon y Cajal, Santiago; Alava, Enrique de; Matias-Guiu, Xavier; Noguera, Rosa (Frontiers Media, 2021)
      The invasive tumor front (the tumor–host interface) is vitally important in malignant cell progression and metastasis. Tumor cell interactions with resident and infiltrating host cells and with the surrounding extracellular ...
    • Chronic obstructive pulmonary disease (COPD) in Spain and the different aspects of its social impact: a multidisciplinary opinion document 

      Bouza, Emilio; Alvar, Agustí; Almagro, Pere; Alonso, Tamara; Ancochea, Julio; Barbé Illa, Ferran; Corbella, Josep; Gracia, Diego; Mascarós, Enrique; Melis, Joan; Miravitlles Fernández, Marc; Pastor, Mariano; Pérez, Patricia; Rudilla, David; Torres, Antoni; Soriano, Joan Bautista; Vallano, Antoni; Vargas, Francisco; Palomo, Esteban (Sociedad Española de Quimioterapia, 2020-02)
      Abstract Chronic obstructive pulmonary disease (COPD) is one of the most prevalent diseases in the World, and one of the most important causes of mortality and morbidity. In adults 40 years and older, it affects more than ...
    • Cierre primario diferido después de eventroplastia complicada 

      Gas Ruiz, Cristina; Villalobos Mori, Rafael; Mias Carballal, Mª Carmen; Escoll Rufino, Jordi; Ros López, Susana; Melé Olivé, Jordi; Escartín Arias, Alfredo; Olsina Kissler, Jorge Juan (Elsevier, 2016)
      La reparación de la hernia incisional gigante requiere una técnica de disección compleja, con un alto riesgo de complicaciones posoperatorias. Presentamos un caso de eventración recidivada en el que se realizó una técnica ...
    • Circadian Patterns of Patients with Type 2 Diabetes and Obstructive Sleep Apnea 

      Cambras, Trinitat; Romero, Odile; Díez Noguera, Antoni; Lecube Torelló, Albert; Sampol, Gabriel (MDPI, 2021)
      Sleep apnea, a condition that modifies sleep and circadian rhythms, is highly prevalent in patients with diabetes. However, it is not known if there is an association between sleep apnea, circadian alterations and glycemic ...