• Incidence of Melanoma in Catalonia, Spain, Is Rapidly Increasing in the Elderly Population. A Multicentric Cohort Study. 

  Podlipnik, Sebastian; Carrera, Cristina; Boada, Aram; Richarz, Nina; Marcoval, Joaquim; Ferreres, Josep Ramón; Bodet, Domingo; Martí Laborda, Rosa Ma.; Segura, Sonia; Sabat, Mireia; Dalmau, Joan; Quintana, Mònica; Azon, Antoni; Curcó, Neus; Formigon, Manel; Olivella-Garcés, María Rosa; Zaballos, Pedro; Sola, Joaquim; Galvany, Loida; Baliu-Piqué, Carola; Alegre, Marta; Pasquali, Paola; Malvehy, Josep; Puig, Susana (MDPI, 2020)

  The incidence of melanoma has been increasing worldwide during recent decades. The objective of the study was to analyse the trends in incidence for in situ and invasive melanoma in the Spanish region of Catalonia during ...

• Frequency and Clinicopathological Profile Associated with Braf Mutations in Patients with Advanced Melanoma in Spain 

  Lopez-Martin, Jose A.; Arance Fernández, Ana; Ríos-Martín, Juan José; Hernández-Losa, Javier; Alós Hernández, Lucía; Cerezuela Fuentes, Pablo; Ortiz Reina, Sebastián; Ortega Izquierdo, Maria Eugenia; Martí Laborda, Rosa Ma.; Soberino García, Jesús; Ferrer Fábrega, Berta; Rodríguez-Peralto, José L.; ABSOLUT-BRAF Study Group (Elsevier, 2020)

  Real-world data on BRAF mutation frequency in advanced melanoma are lacking in Spain. Moreover, data available on clinicopathological profile of patients with advanced BRAF-mutant melanoma are currently limited. This study ...

• WNT11-FZD7-DAAM1 signalling supports tumour initiating abilities and melanoma amoeboid invasion 

  Rodriguez-Hernandez, Irene; Maiques Carlos, Oscar; Kohlhammer, Leonie; Cantelli, Gaia; Perdrix-Rosell, Anna; Monger, Joanne; Fanshawe, Bruce; Bridgeman, Victoria L.; Karagiannis, Sophia N.; Penin, Rosa M.; Marcolval, Joaquim; Martí Laborda, Rosa Ma.; Matias-Guiu, Xavier; Fruhwirth, Gilbert O.; Orgaz, Jose L.; Malanchi, Ilaria; Sanz Moreno, Victoria (Nature Research, 2020)

  Melanoma is a highly aggressive tumour that can metastasize very early in disease progression. Notably, melanoma can disseminate using amoeboid invasive strategies. We show here that high Myosin II activity, high levels ...

• Evaluación del grado de adherencia a las recomendaciones nutricionales en el paciente crítico 

  Servià Goixart, Lluís; López Delgado, Juan Carlos; Grau Carmona, Teodoro (Aran Ediciones, 2019-06-01)

  Objetivo: la aplicación del soporte nutricional especializado (SNE) es difícil a nivel organizativo debido a la complejidad de las guías de práctica clínica y desconocemos el grado de adherencia a las recomendaciones ...

• Nivel de conocimiento de la enfermedad de Alzheimer en cuidadores y población general 

  Jorge, C.; Cetó, M.; Arias, A.; Blasco, E.; Gil, M. P.; López, R.; Dakterzada, Farida; Purroy Garcia, Francisco; Piñol Ripoll, Gerard (Elsevier, 2019-05-11)

  Introducción El conocimiento de la enfermedad de Alzheimer es fundamental para el diagnóstico precoz y para reducir la sobrecarga del cuidador. El objetivo fue evaluar el grado de conocimiento de la enfermedad de Alzheimer ...

• IL-17A as a potential therapeutic target for patients on peritoneal dialysis 

  Marchant, Vanessa; Tejera Muñoz, Antonio; Marquez Exposito, Laura; Rayego Mateos, Sandra; Rodrigues-Diez, Raul; Tejedor, Lucia; Santos Sanchez, Laura; Egido, Jesús; Valdivielso Revilla, José Manuel; Fraser, Donald J.; López Cabrera, Manuel; Selgas, Rafael; Ruiz-Ortega, Marta (MDPI, 2020)

  Chronic kidney disease (CKD) is a health problem reaching epidemic proportions. There is no cure for CKD, and patients may progress to end-stage renal disease (ESRD). Peritoneal dialysis (PD) is a current replacement therapy ...

• Prediabetes is independently associated with subclinical carotid atherosclerosis: an observational study in a non-urban mediterranean population 

  Vilanova, María-Belén; Franch-Nadal, Josep; Falguera, Mireia; Marsal Mora, Josep Ramon; Canivell, Sílvia; Rubinat, Esther; Miró, Neus; Molló Inesta, Àngels; Mata Cases, Manel; Gratacòs, Mònica; Castelblanco Echavarría, Esmeralda; Mauricio Puente, Dídac (MDPI, 2020)

  This was a prospective, observational study to compare the burden of subclinical atherosclerosis as measured by carotid ultrasonography in a cohort of subjects with prediabetes vs. subjects with normal glucose tolerance ...

• Editorial: diabetes and obesity effects on lung function 

  Chen, Xiaofeng; Yan, Liangjun; Lecube Torelló, Albert; Tang, Xiaoqiang (Frontiers Media, 2020)

• REMOTE ischemic perconditioning among acute ischemic stroke patients in Catalonia: REMOTE-CAT PROJECT 

  Purroy Garcia, Francisco; Arque, Gloria; Mauri-Capdevila, Gerard; García-Vázquez, Cristina; Vicente-Pascual, Mikel; Pereira, Cristina; Vazquez-Justes, Daniel; Torres-Querol, Coral; Vena Martínez, Ana Belén; Abilleira, Sònia; Cardona, Pere; Forné, Carles; Jiménez-Fàbrega, Xavier; Pagola, Jorge; Portero-Otin, Manuel; Rodríguez-Campello, Ana; Rovira, Àlex; Fàbregas, Joan Martí (Frontiers Media, 2020)

  Rationale: Remote ischemic perconditioning during cerebral ischemia (RIPerC) refers to the application of brief episodes of transient limb ischemia commonly to a limb, it represents a new safe, simple and low-cost paradigm ...

• Inflammatory response of ischemic tolerance in circulating Plasma: preconditioning-Induced by transient ischemic attack (TIA) phenomena in acute ischemia patients (AIS) 

  Colàs Campàs, Laura; Farré, Joan; Mauri-Capdevila, Gerard; Molina Seguin, Jessica; Aymerich, Núria; Ois, Ángel; Roquer, Jaume; Tur, Silvia; García-Carreira, María del Carmen; Martí-Fàbregas, Joan; Cruz-Culebras, Antonio; Segura, Tomás; Arque, Gloria; Purroy Garcia, Francisco (Frontiers Media, 2020)

• Valor social de los medicamentos para dejar de fumar. Opiniones respecto a su financiación 

  Abella i Pons, Francesc; Gil, Juan; Pedra, Gerard (Asociación Española de Estudio en Drogodependencias (AESED), 2020)

  Las medidas de la OMS para controlar el tabaquismo han disminuido su prevalencia, pero aumentando las diferencias entre grupos sociales. Facilitar el acceso a los medicamentos, para dejar de fumar, a los desfavorecidos ...

• Chronic obstructive pulmonary disease (COPD) in Spain and the different aspects of its social impact: a multidisciplinary opinion document 

  Bouza, Emilio; Alvar, Agustí; Almagro, Pere; Alonso, Tamara; Ancochea, Julio; Barbé Illa, Ferran; Corbella, Josep; Gracia, Diego; Mascarós, Enrique; Melis, Joan; Miravitlles Fernández, Marc; Pastor, Mariano; Pérez, Patricia; Rudilla, David; Torres, Antoni; Soriano, Joan Bautista; Vallano, Antoni; Vargas, Francisco; Palomo, Esteban (Sociedad Española de Quimioterapia, 2020-02)

  Abstract Chronic obstructive pulmonary disease (COPD) is one of the most prevalent diseases in the World, and one of the most important causes of mortality and morbidity. In adults 40 years and older, it affects more than ...

• Trends in the consumption rates of benzodiazepines and benzodiazepine-related drugs in the health region of Lleida from 2002 to 2015 

  Torres Bondia, F.; Batlle Garcia, Jordi de; Galván, Leonardo; Buti, Miquel; Barbé Illa, Ferran; Piñol Ripoll, Gerard (Biomed Central, 2020-06-01)

  Background: The high prevalence and long-term use of benzodiazepines (BZDs) treatment are debated topics because of the risk they can cause to the patients. Despite the current information on the risk-benefit balance of ...

• Long-term Noninvasive Ventilation in Obesity Hypoventilation Syndrome Without Severe OSA: The Pickwick Randomized Controlled Trial 

  Masa, Juan F.; Benítez, Iván; Sánchez-Quiroga, Maria Á.; Gomez de Terreros, Francisco J.; Corral-Peñafiel, Jaime; Romero, Auxiliadora; Caballero-Eraso, Candela; Alonso-Álvarez, Maria L.; Ordax-Carbajo, Estrella; Gomez-Garcia, Teresa; González, Mónica; López-Martín, Soledad; Marin, José M.; Martí, Sergi; Díaz Cambriles, Trinidad; Chiner, Eusebi; Egea, Carlos; Barca, Javier; Vázquez-Polo, Francisco Javier; Negrín, Miguel Ángel; Martel-Escobar, María; Barbé Illa, Ferran; Mokhlesi, Babak; Spanish Sleep Network (Elsevier, 2020-04-25)

  Background: Noninvasive ventilation (NIV) is an effective form of treatment in obesity hypoventilation syndrome (OHS) with severe obstructive sleep apnea (OSA). However, there is paucity of evidence in OHS patients without ...

• Effect of Type 2 Diabetes Mellitus on the Hypoxia-Inducible Factor 1-Alpha Expression. Is There a Relationship with the Clock Genes? 

  López Cano, Carolina; Gutiérrez Carrasquilla, Liliana; Barbé Illa, Ferran; Sánchez Peña, Enric; Hernández García, Marta; Martí, Raquel; Ceperuelo-Mallafre, Vicky; Dalmases, Mireia; Fernández-Veledo, Sonia; Vendrell, Joan; Hernández, Cristina; Simó, Rafael; Lecube Torelló, Albert (MDPI, 2020)

  Limited reports exist on the relationships between regulation of oxygen homeostasis and circadian clock genes in type 2 diabetes. We examined whether the expression of Hypoxia-Inducible Factor-1α (HIF-1α) and HIF-2α ...

• Advanced lipoprotein profle disturbances in type 1 diabetes mellitus: a focus on LDL particles 

  Amor, Antonio J.; Castelblanco Echavarría, Esmeralda; Hernández, Marta; Gimenez, Marga; Granado Casas, Minerva; Blanco, Jesús; Soldevila, Berta; Esmatjes, Enric; Conget, Ignacio; Alonso, Núria; Ortega, Emilio; Mauricio Puente, Dídac (BioMed Central, 2020)

  Background: Lipoprotein disturbances have been associated with increased cardiovascular disease (CVD) risk in type 1 diabetes mellitus (T1DM). We assessed the advanced lipoprotein profle in T1DM individuals, and analysed ...

• Adaptation and Validation of the Diabetic Foot Ulcer Scale-Short Form in Spanish Subjects 

  Martínez González, María Dolores; Dòria, Montserrat; Martínez Alonso, Montserrat; Alcubierre Calvo, Núria; Valls, Joan; Verdú-Soriano, José; Granado Casas, Minerva; Mauricio Puente, Dídac (MDPI, 2020)

  Diabetic foot ulcer (DFU) is a chronic complication that negatively affects the quality of life (QoL) of diabetic patients. In Spain, there is no specifically designed and validated instrument to assess the QoL of patients ...

• New Metrics to Assess Type 2 Diabetes after Bariatric Surgery: The “Time-Within-Remission Range” 

  de Hollanda, Ana; Lecube Torelló, Albert; Rubio, Miguel Ángel; Sánchez Peña, Enric; Vilarrasa, Núria; Gregorio Oliva, José; Fernández-Soto, María Luisa; Salas-Salvadó, Jordi; Ballesteros-Pomar, María D.; Ciudin, Andreea; Torres, Ferran; Vidal, Concepción; Morales, María José; Valdés, Sergio; Pellitero, Silvia; Miñambres, Inka; Masmiquel, Lluís; Goday, Albert; Suarez, Lorena; Flores, Liliam; Bueno Díez, Marta; Caixàs, Assumpta; Bretón, Irene; Cámara, Rosa; Olbeyra, Romina; Penso, Rona; de la Cruz, María José; Simó-Servat, Andreu; Pereyra-García, Francisca María; López-Mezquita, Elena Teresa; Gils, Anna; Fidilio, Enzamaria; Bandrés, Orosia; Martínez, Ángel; Abuín, Jose; Marques-Pamies, Montserrat; Tuneu, Laura; Arteaga, Magdalena; Castañer, Olga; Goñi, Fernando; Arrizabalaga, Cristina; Botana, Manuel Antonio; Calañas, Alfonso (MDPI, 2020)

  Almost one third of patients do not achieve type 2 diabetes remission after bariatric surgery or are unable to sustain this effect long term. Our objective was to delve further into the dynamic responses of diabetes after ...

• Factors Accounting for Obesity and Its Perception among the Adult Spanish Population: Data from 1,000 Computer-Assisted Telephone Interviews 

  Lecube Torelló, Albert; Sánchez Peña, Enric; Monereo, Susana; Medina-Gómez, Gema; Bellido, Diego; García-Almeida, José Manuel; Martínez de Icaya, Purificación; Malagón, Maria Mar; Goday, Albert; Tinahones, Francisco José (Karger Publishers, 2020)

  Objective: Our aim was to go deeper in the self-perception of weight and health status among the Spanish population, together with the connections of familiar relationships, physical activity practice, nutritional habits, ...

• Induced neuroprotection by remote ischemic perconditioning as a new paradigm in ischemic stroke at the acute phase, a systematic review 

  Purroy Garcia, Francisco; García, Cristina; Mauri-Capdevila, Gerard; Pereira, Cristina; Torres, Coral; Vazquez-Justes, Daniel; Vicente-Pascual, Mikel; Vena Martínez, Ana Belén; Arque, Gloria (BMC, 2020)

  Background: Remote ischemic conditioning during cerebral ischemia (remote ischemic perconditioning, RIPerC) refers to the application of several cycles of brief ischemia and reperfusion (I/R) commonly to a limb, and it ...

View more