Articles publicats (Medicina)
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Cardiovascular risk factors and the impact on prognosis in patients with chronic kidney disease secondary to autosomal dominant polycystic kidney disease
(BMC, 2021)Background: Autosomal dominant polycystic kidney disease (ADPKD) is the most frequent hereditary renal disease. There is an increased rate of cardiovascular disease (CVD) in ADPKD. In this study, we evaluate the prevalence ... -
Use and Safety of Remdesivir in Kidney Transplant Recipients With COVID-19
(Elsevier, 2021)Introduction:Remdesivir has demonstrated antiviral activity against coronavirus, shortening the time torecovery in adults hospitalized with moderate/severe COVID-19. Severe adverse events such as acutekidney injury have ... -
High Incidence of Adverse Outcomes in Haemodialysis Patients with Diabetes with or without Diabetic Foot Syndrome: A 5-Year Observational Study in Lleida, Spain
(MDPI, 2021)Background: We evaluated whether, in subjects receiving haemodialysis (HD), the presence of diabetic foot syndrome (DFS) was associated with increased mortality compared with subjects with diabetes mellitus (DM) without ... -
Characterisation of the inflammatory response triggered by topical ingenol mebutate 0.05% gel in basal cell carcinoma
(WileyAustralasian College of Dermatologists, 2020-01-16)Background/Objective Ingenol mebutate gel is approved for actinic keratosis field therapy, but little has been published as a treatment of basal cell carcinoma (BCC). Our objective is to characterise the histopathological ... -
An N-ethyl-N-Nitrosourea Mutagenesis Screen in Mice Reveals a Mutation in Nuclear Respiratory Factor 1 (Nrf1) Altering the DNA Methylation State and Correct Embryonic Development
(MDPI, 2021)We have established a genome-wide N-ethyl-N-nitrosourea (ENU) mutagenesis screen to identify novel genes playing a role in epigenetic regulation in mammals. We hypothesize that the ENU mutagenesis screen will lead to the ... -
Gut microbiota resilience in horse athletes following holidays out to pasture
(Nature Portfolio, 2021)Elite horse athletes that live in individual boxes and train and compete for hours experience long-term physical and mental stress that compromises animal welfare and alters the gut microbiota. We therefore assessed if a ... -
Particle size and cholesterol content of circulating HDL correlate with cardiovascular death in chronic heart failure
(Nature Portfolio, 2021)Evidence regarding any association of HDL-particle (HDL-P) derangements and HDL-cholesterol content with cardiovascular (CV) death in chronic heart failure (HF) is lacking. To investigate the prognostic value of HDL-P size ... -
Endometrial PTEN Deficiency Leads to SMAD2/3 Nuclear Translocation
(MDPI, 2021-10-05)TGF-β has a dichotomous function, acting as tumor suppressor in premalignant cells but as a tumor promoter for cancerous cells. These contradictory functions of TGF-β are caused by different cellular contexts, including ... -
Sex-Related Differences in Clinical Features, Neuroimaging, and Long-Term Prognosis After Transient Ischemic Attack
(American Heart Association, 2021)Differences in sex in the incidence, presentation, and outcome of events after ischemic stroke have been studied in depth. In contrast, only limited data are available after transient ischemic attack (TIA). We aim to assess ... -
Circadian Patterns of Patients with Type 2 Diabetes and Obstructive Sleep Apnea
(MDPI, 2021)Sleep apnea, a condition that modifies sleep and circadian rhythms, is highly prevalent in patients with diabetes. However, it is not known if there is an association between sleep apnea, circadian alterations and glycemic ... -
Obesity in Patients with Type 1 Diabetes: Links, Risks and Management Challenges
(Dove Medical Press, 2021)Obesity affects large numbers of patients with type 1 diabetes (T1D) across their lifetime, with rates ranging between 2.8% and 37.1%. Patients with T1D and obesity are characterized by the presence of insulin resistance, ... -
Eutanasia: ¿es esta la ley que necesitamos?
(Elsevier, 2021)La Ley de Eutanasia española introduce un nuevo derecho que se incorpora a la cartera de servicios del sistema sanitario, como una prestación cuya aplicación se garantiza en el plazo de 40 días. Desde la experiencia clínica ... -
Prevalence, clinical characteristics, and outcome of pleural effusions in ovarian cancer
(De Gruyter, 2021)Objectives: The prevalence, clinical characteristics and prognosis of pleural effusions (PEs) associated with ovarian cancer (OC) have seldom been addressed systematically, as in the current investigation. Methods: All ... -
Non‑linear association of anthropometric measurements and pulmonary function
(Nature Research, 2021)This study examined the association of anthropometric measurements [body mass index (BMI), waist circumference (WC), percentage body fat (PBF), body roundness index (BRI) and A Body Shape Index (ABSI)] with pulmonary ... -
Characterizing the Invasive Tumor Front of Aggressive Uterine Adenocarcinoma and Leiomyosarcoma
(Frontiers Media, 2021)The invasive tumor front (the tumor–host interface) is vitally important in malignant cell progression and metastasis. Tumor cell interactions with resident and infiltrating host cells and with the surrounding extracellular ... -
Identifying thoracic malignancies through pleural fluid biomarkers: a predictive multivariate model
(Wolters Kluwer Health, 2016-03-01)The diagnosis of malignant pleural effusions may be challenging when cytological examination of aspirated pleural fluid is equivocal or noncontributory. The purpose of this study was to identify protein candidate biomarkers ... -
Ganancia de peso durante el confinamiento por la COVID-19; encuesta de la Sociedad Española de Obesidad
(Sociedad Española de Cirugía de Obesidad y Metabólica y Sociedad Española para el Estudio de la Obesidad, 2020-11-01)La obesidad, después de la edad, es el principal factor de mal pronóstico durante la infección por la COVID-19. El confinamiento al que la población española ha sido expuesta durante varias semanas puede ser una causa de ... -
Revisión sistemática del síndrome de Münchhausen por poderes o trastorno facticio impuesto a otro: psicobiografía de la perpertradora, el proceso de peregrinación hospitalaria y signos de alarma en la víctima
(Sociedad Española de Medicina Psicosomática, 2020-10)INTRODUCCIÓN: En 1977, Roy Medow acuña y describe el síndrome de Münchhausen por poderes como una enfermedad mental en la que una cuidadora miente al doctor sobre la salud de su hijo mediante la fabricación de signos ... -
Effect of CPAP Therapy on 24-Hour Intraocular Pressure-Related Pattern From Contact Lens Sensors in Obstructive Sleep Apnea Syndrome
(Association for Research in Vision and Ophthalmology, 2021-04-01)Purpose: To evaluate the effect of continuous positive airway pressure (CPAP) therapy on 24-hour intraocular pressure (IOP)-related pattern from contact lens sensors (CLS) in obstructive sleep apnea syndrome (OSAS). Methods: ... -
Influence of thromboembolic events in the prognosis of COVID-19 hospitalized patients. Results from a cross sectional study
(Public Library of Science, 2021)Background COVID-19 may predispose to both venous and arterial thromboembolism event (TEE). Reports on the prevalence and prognosis of thrombotic complications are still emerging. Objective To describe the rate of TEE ...