• Impact of One-Catheter Strategy with TIG I Catheter on Coronary Catheterization Performance and Economic Costs 

  Costa-Mateu, Joan; Fernández-Rodríguez, Diego; Rivera, Kristian; Casanova, Juan; Irigaray, Patricia; Zielonka, Marta; Pereyra-Acha, Eduardo; Aldomá, Albina; Worner, Fernando (Sociedade Brasileira de Cardiologia, 2019)

  Background: Coronary angiography with two catheters is the traditional strategy for diagnostic coronary procedures. TIG I catheter permits to cannulate both coronary arteries, avoiding exchanging catheters during coronary ...

• Design, optimization and validation of genes commonly used in expression studies on DMH/AOM rat colon carcinogenesis model 

  Bars Cortina, David; Riera-Escamilla, Antoni; Gou, Gemma; Piñol Felis, Carme; Motilva Casado, Mª José (PeerJ, 2019-01-29)

  Colorectal cancer (CRC), also known as colon cancer, is the third most common form of cancer worldwide in men and the second in women and is characterized by several genetic alterations, among them the expression of several ...

• Sympathetic Hyperactivity and Sleep Disorders in Individuals With Type 2 Diabetes 

  López Cano, Carolina; Gutiérrez Carrasquilla, Liliana; Sánchez Peña, Enric; González, Jessica; Yeramian Hakim, Andree; Martí, Raquel; Hernández García, Marta; Cao, Gonzalo; Ribelles, Mercè; Gómez Arbonés, Javier; Barril, Silvia; Barbé Illa, Ferran; Hernández, Cristina; Simó, Rafael; Lecube Torelló, Albert (Frontiers Medica, 2019)

  Introduction: Many studies on the impact of type 2 diabetes mellitus (T2DM) on sleep breathing have shown a higher prevalence and severity of sleep apnea-hypopnea syndrome (SAHS) in those with T2DM. Moreover, an increased ...

• Depression and Apathy After Transient Ischemic Attack or Minor Stroke: Prevalence, Evolution and Predictors 

  Carnes Vendrell, Anna; Deus Yela, Juan; Molina Seguin, Jessica; Pifarré Paredero, Josep; Purroy Garcia, Francisco (Nature Research, 2019)

  Few previous studies have focused on affective impairment after transient ischemic attack (TIA) and/or minor stroke. The aim was to establish the prevalence, evolution and predictors of post-stroke depression (PSD) and ...

• EV-associated miRNAs from pleural lavage as potential diagnostic biomarkers in lung cancer 

  Roman-Canal, Berta; Moiola, Cristian P.; Gatius Calderó, Sònia; Bonnin, Sarah; Ruiz Miró, Maria; González, Esperanza; Ojanguren, Amaia; Recuero, José Luis; Gil-Moreno, Antonio; Falcón-Pérez, Juan M.; Ponomarenko, Julia; Porcel Pérez, José Manuel; Matias-Guiu, Xavier; Colas, Eva (Nature Research, 2019)

  Lung cancer is the leading cause of cancer-related deaths among men and women in the world, accounting for the 25% of cancer mortality. Early diagnosis is an unmet clinical issue. In this work, we focused to develop a ...

• Genome-Wide Association Study of VKORC1 and CYP2C9 on acenocoumarol dose, stroke recurrence and intracranial haemorrhage in Spain 

  Cullell, Natalia; Carrera, Caty; Muiño, Elena; Torres-Aguila, Nuria-Paz; Cárcel-Márquez, Jara; González-Sánchez, Jonathan; Gallego Fabrega, Cristina; Molina, Jessica; Besora, Sarah; Sotoca, Javier; Buongiorno, Maria-Teresa; Jiménez-Conde, Jordi; Giralt-Steinhauer, Eva; de Torres-Chacón, Reyes; Montaner, Joan; Mancha, Fernando; Cabezas, Juan A.; Martí Fàbregas, Joan; Prats Sánchez, Luis; Camps Renom, Pol; Purroy Garcia, Francisco; Cambray Carner, Serafí; Freijo, María del Mar; Vives-Bauzá, Cristòfol; Tur, Silvia; Font, Maria-Àngels; López-Cancio, Elena; Hernandez-Perez, Maria; Obach, Victor; Calleja, Ana; Arenillas, Juan; Rodríguez-Yáñez, Manuel; Castillo, José; Sobrino, Tomas; Fernández-Cádenas, Israel; Krupinski, Jerzy (Nature Publishing Group, 2020)

  Acenocoumarol is an oral anticoagulant with significant interindividual dose variations. Variants in CYP2C9 and VKORC1 have been associated with acenocoumarol maintenance dose. We analysed whether any of the 49 polymorphisms ...

• Skin Autofluorescence Measurement in Subclinical Atheromatous Disease: Results from the ILERVAS Project 

  Sánchez Peña, Enric; Betriu i Bars, M. Àngels; Yeramian Hakim, Andree; Fernández i Giráldez, Elvira; Purroy Garcia, Francisco; Sánchez de la Torre, Manuel; Pamplona Gras, Reinald; Miquel, Eva; Kerkeni, M.; Hernández, Cristina; Simó, Rafael; Lecube Torelló, Albert (Japan Atherosclerosis Society, 2019)

  AIM: Advanced glycation end-products (AGEs) have been involved in the atherogenic process in the high-risk population. The goal of this study was to demonstrate that AGEs are related to subclinical atheromatous disease in ...

• Assessment of Inner Retinal Layers and Choroidal Thickness in Type 1 Diabetes Mellitus: A Cross-Sectional Study 

  Carbonell, Marc; Alonso, Núria; Castelblanco Echavarría, Esmeralda; Real, Jordi; Ramírez-Morros, Anna; Simó, Rafael; Hernández, Cristina; Jurjo Campo, Carmen; Traveset Maeso, Alicia; Valldeperas, Xavier; Mauricio Puente, Dídac (MDPI, 2019)

  Recent studies have shown that retinal neurodegeneration may precede visible vascular changes in diabetic retinopathy (DR). In addition, the relationship of choroidal thickness (CT) with DR stage is not well defined. To ...

• Obesity, a Diet-Induced Inflammatory Disease 

  Lecube Torelló, Albert; López Cano, Carolina (MDPI, 2019)

• Circulating microRNA profile as a potential biomarker for obstructive sleep apnea diagnosis 

  Santamaria-Martos, Fernando; Benítez, Iván; Ortega, Francisco; Zapater, Andrea; Giron, Cristina; Pinilla, Lucía; Pacual, Lydia; Cortijo, Anunciación; Dalmases, Mireia; Fernandez-Real, Jose Manuel; Barbé Illa, Ferran; Sánchez de la Torre, Manuel (Nature Publishing Group, 2019)

  Evaluation of microRNAs (miRNAs) could allow characterization of the obstructive sleep apnea (OSA) and help diagnose it more accurately. We aimed to examine circulating miRNA profiles to establish the differences between ...

• Impairment of Mitochondrial Redox Status in Peripheral Lymphocytes of Multiple Sclerosis Patients 

  Gonzalo Benito, Hugo; Nogueras, L.; Gil-Sánchez, Anna; Vicente Hervás, José; Valcheva, Petya; González Mingot, Cristina; Martin-Gari, Meritxell; Canudes, Marc; Peralta Moncusí, Silvia; Solana Moga, M. José; Pamplona Gras, Reinald; Portero Otín, Manuel; Boada Pallàs, Jordi; Serrano Casasola, José Carlos Enrique; Brieva Ruiz, Luis (Frontiers Media, 2019)

  Literature suggests that oxidative stress (OS) may be involved in the pathogenesis of multiple sclerosis (MS), in which the immune system is known to play a key role. However, to date, the OS in peripheral lymphocytes and ...

• Genetic Testing to Predict Weight Loss and Diabetes Remission and Long-Term Sustainability after Bariatric Surgery: A Pilot Study 

  Ciudin, Andreea; Fidilio, Enzamaria; Ortiz, Angel; Pich, Sara; Salas, Eduardo; Mesa, Jordi; Hernández, Cristina; Simó-Servat, Olga; Lecube Torelló, Albert (2019)

  Introduction: The aim of this pilot study was to assess genetic predisposition risk scores (GPS) in type 2 diabetic and non-diabetic patients in order to predict the better response to bariatric surgery (BS) in terms of ...

• EV-associated miRNAs from peritoneal lavage as potential diagnostic biomarkers in colorectal cancer 

  Roman-Canal, Berta; Tarragona Foradada, Jordi; Moiola, Cristian P.; Gatius Calderó, Sònia; Bonnin, Sarah; Ruiz Miró, Maria; Sierra, José Enrique; Rufas, Maria; González, Esperanza; Porcel Pérez, José Manuel; Gil-Moreno, Antonio; Falcon-Perez, Juan M.; Ponomarenko, Julia; Matias-Guiu, Xavier; Colas, Eva (BioMed Central, 2019)

  Background: Colorectal cancer (CRC) is the third leading cause of cancer-related mortality worldwide. Current systematic methods for diagnosing have inherent limitations so development of a minimally-invasive diagnosis, ...

• A prospective study examining cachexia predictors in patients with incurable cancer 

  Vagnildhaug, Ola Magne; Brunelli, Cinzia; Hjermstad, Marianne J.; Strasser, Florian; Baracos, Vickie; Wilcock, Andrew; Nabal Vicuña, Maria; Kaasa, Stein; Laird, Barry; Solheim, Tora S. (BioMed Central, 2019)

  Background: Early intervention against cachexia necessitates a predictive model. The aims of this study were to identify predictors of cachexia development and to create and evaluate accuracy of a predictive model based ...

• Subcutaneous advanced glycation end-products and lung function according to glucose abnormalities: The ILERVAS project 

  Sánchez Peña, Enric; Lecube Torelló, Albert; Betriu i Bars, M. Àngels; Hernández, Cristina; López Cano, Carolina; Gutiérrez Carrasquilla, Liliana; Kerkeni, M.; Yeramian Hakim, Andree; Purroy Garcia, Francisco; Pamplona Gras, Reinald; Farràs, Cristina; Fernández i Giráldez, Elvira; Barbé Illa, Ferran; Simó, Rafael (Elsevier, 2019-12-01)

• Characteristics of atheromatosis in the prediabetes stage: a cross-sectional investigation of the Ilervas project 

  Sánchez Peña, Enric; Betriu i Bars, M. Àngels; López Cano, Carolina; Hernández García, Marta; Fernández i Giráldez, Elvira; Purroy Garcia, Francisco; Bermúdez López, Marcelino; Farràs-Sallés, Cristina; Barril, Silvia; Pamplona Gras, Reinald; Rius, Ferran; Hernández, Cristina; Simó, Rafael; Lecube Torelló, Albert (BioMed Central, 2019-11-15)

  BACKGROUND: Prediabetes has recently been associated with subclinical atheromatous disease in the middle-aged population. Our aim was to characterize atheromatous plaque burden by the number of affected territories and the ...

• Dissimilar impact of Mediterranean diet and physical activity on estimated body composition: A cross-sectional study from the ILERVAS project 

  Sánchez, Marta; Sánchez Peña, Enric; Hernández García, Marta; González, Jessica; Purroy Garcia, Francisco; Rius, Ferran; Pamplona Gras, Reinald; Farràs-Sallés, Cristina; Gutiérrez Carrasquilla, Liliana; Fernández i Giráldez, Elvira; Bermúdez López, Marcelino; Salvador, Javier; Salas-Salvadó, Jordi; Lecube Torelló, Albert (MDPI, 2019-06-17)

  There is a close relationship between lifestyle behaviors and excess adiposity. Althoughbody mass index (BMI) is the most used approach to estimate excess weight, other anthropometricindices have been developed to ...

• Prevalence of pre-diabetes and undiagnosed diabetes in the Mollerussa prospective observational cohort study in a semi-rural area of Catalonia 

  Falguera, Mireia; Vilanova, María-Belén; Alcubierre Calvo, Núria; Granado Casas, Minerva; Marsal Mora, Josep Ramon; Miró, Neus; Cebrian, Cristina; Molló Inesta, Àngels; Franch-Nadal, Josep; Mata Cases, Manel; Castelblanco Echavarría, Esmeralda; Mauricio Puente, Dídac (BMJ, 2020-01-07)

  Objectives: To assess the prevalence of undiagnosed diabetes and pre-diabetes in the healthy population in the Mollerussa cohort. As a secondary objective, to identify the variables associated with these conditions and to ...

• A prospective pilot study using metabolomics discloses specific fatty acid, catecholamine and tryptophan metabolic pathways as possible predictors for a negative outcome after severe trauma 

  Servià Goixart, Lluís; Jové Font, Mariona; Sol, Joaquim; Pamplona Gras, Reinald; Badia Castello, Mariona; Montserrat, Neus; Portero Otín, Manuel; Trujillano Cabello, Javier (BMC (part of Springer Nature), 2019-05-22)

  Background: We wanted to define metabolomic patterns in plasma to predict a negative outcome in severe trauma patients. Methods: A prospective pilot study was designed to evaluate plasma metabolomic patterns, established ...

• Circulating Soluble CD36 is Similar in Type 1 and Type 2 Diabetes Mellitus versus Non-Diabetic Subjects 

  Castelblanco Echavarría, Esmeralda; Sanjurjo, Lucía; Falguera, Mireia; Hernández García, Marta; Fernandez-Real, Jose Manuel; Sarrias, Maria-Rosa; Alonso, Núria; Mauricio Puente, Dídac (MDPI, 2019-05)

  The aim of this study was to determine whether plasma concentrations of sCD36 (soluble CD36) are associated with the presence of type 1 or type 2 diabetes. Plasma levels of sCD36 were analysed in 1023 subjects (225 type 1 ...

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