• VIH en España 2017: políticas para una nueva gestión de la cronicidad más allá del control virológico 

  Gol-Montserrat, Jordi; Llano, Juan E. del; Amo, Julia del; Campbell, Colin; Navarro, Gemma; Segura, Ferrán; Suárez Lozano, Ignacio; Teira, Ramón; Brañas, Fátima; Serrano-Villar, Sergio; Moreno, Santiago; Morillo, Ramón; Fernández i Giráldez, Elvira; Marco Mayayo, M. Paz; Blanch, Jordi; Castaño Carracedo, Manuel; Pujol, Ferran; Fuster, Mª José; Hernández, Juan Sebastián; García-Goñi, Manuel; Nuño-Solinís, Roberto; Elizondo, Nerea (Ministerio de Sanidad y Consumo, 2018)

  El análisis de las bases de datos disponibles relacionadas con VIH/ SIDA confirma un cambio de paradigma en la esperanza de vida del paciente: ahora el VIH se ha convertido en una enfermedad crónica, con la que los pacientes ...

• Relationship between low levels of circulating TRAIL and atheromatosis progression in patients with chronic kidney disease. 

  Arcidiacono, Maria V.; Rimondi, Erika; Maietti, Elisa; Melloni, Elisabetta; Tisato, Veronica; Gallo, Stefania; Valdivielso Revilla, José Manuel; Fernández i Giráldez, Elvira; Betriu i Bars, M. Àngels; Voltan, Rebecca; Zauli, Giorgio; Volpato, Stefano; Secchiero, Paola (Public Library of Science, 2018-09-11)

  Background: Chronic kidney disease (CKD) patients experience a high risk of cardiovascular disease (CV); however, the factors involved in CV-related morbidity and mortality in these patients have not been fully defined. ...

• Biomarkers in the diagnosis of pleural diseases: a 2018 update 

  Porcel Pérez, José Manuel (SAGE Publications, 2018)

  The use of biomarkers on pleural fluid (PF) specimens may assist the decision-making process and enhance clinical diagnostic pathways. Three paradigmatic examples are heart failure, tuberculosis and, particularly, malignancy. ...

• Correction: The modality of dialysis does not influence atheromatous vascular disease progression or cardiovascular outcomes in dialysis patients without previous cardiovascular disease. 

  Borràs, Mercè; Pérez Fontán, Miguel; Martínez Alonso, Montserrat; Bajo, Auxiliadora; Betriu i Bars, M. Àngels; Valdivielso Revilla, José Manuel; Fernández i Giráldez, Elvira (Public Library of Science, 2018-06-28)

• Development and Management of Networks of Care at the End of Life (the REDCUIDA Intervention): Protocol for a Nonrandomized Controlled Trial 

  Librada Flores, Silvia; Herrera Molina, Emilio; Díaz Díez, Fátima; Redondo Moralo, María José; Castillo Rodríguez, Cristina; McLoughlin, Kathleen; Abel, Julian; Nabal Vicuña, Maria; Jadad Garcia, Tamen; Lucas Díaz, Miguel Ángel; Trabado Lara, Inmaculada; Guerra-Martín, María Dolores (JMIR Publications, 2018)

  Background: End-of-life needs can be only partly met by formalized health and palliative care resources. This creates the opportunity for the social support network of family and community to play a crucial role in this ...

• Severe alpha-1 antitrypsin deficiency in composite heterozygotes inheriting a new splicing mutation QOMadrid 

  Lara Gallego, Beatriz; Martínez, María Teresa; Blanco, Ignacio; Hernández, Cristina; Velasco, Eladio; Ferrarotti, Ilaria; Rodríguez, Francisco; Perez, Laura; Vazquez, Irene; Alonso, Javier; Posada, Manuel; Martínez-Delgado, Beatriz (BioMed Central, 2014)

  [Background]: Severe Alpha-1 Antitrypsin (AAT) deficiency is a hereditary condition caused by mutations in the SERPINA1 gene, which predisposes to lung emphysema and liver disease. It is usually related to PI*Z alleles, ...

• Location-dependent effects of trauma on oxidative stress in humans 

  Servià Goixart, Lluís; Serrano Casasola, José Carlos Enrique; Pamplona Gras, Reinald; Badia Castello, Mariona; Montserrat, Neus; Portero Otín, Manuel; Trujillano Cabello, Javier (Public Library of Science, 2018)

  Though circulating antioxidant capacity in plasma is homeostatically regulated, it is not known whether acute stressors (i.e. trauma) affecting different anatomical locations could have quantitatively different impacts. ...

• Cross-sectional study of the association between healthcare professionals’ empathy and burnout and the number of annual primary care visits per patient under their care in Spain 

  Yuguero Torres, Oriol; Melnick, Edward R; Marsal Mora, Josep Ramon; Esquerda i Aresté, Montse; Soler González, Jorge (BMJ Publishing Group, 2018)

  Objective The aim of this study was to evaluate the association between physician and nurse self-reported empathy and burnout and the number of annual primary care visits per patient under their care. Methods Design: A ...

• Aging is associated with increased FGF21 levels but unaltered FGF21 responsiveness in adipose tissue 

  Villarroya, Joan; Villarroya, Francesc; Gallego-Escuredo, José M.; Delgado‐Anglés, Alejando; Cairó, Montserrat; Moure, Ricardo; Mateo, Gracia M.; Domingo, Joan C.; Domingo, Pere; Giralt, Marta (Wiley Open Access, 2018)

  Fibroblast growth factor 21 (FGF21) has been proposed to be an antiaging hormone on the basis of experimental studies in rodent models. However, circulating FGF21 levels are increased with aging in rodents and humans. ...

• Erectile dysfunction in obstructive sleep apnea patients: A randomized trial on the effects of Continuous Positive Airway Pressure (CPAP) 

  Pascual, Mercè; Batlle Garcia, Jordi de; Barbé Illa, Ferran; Castro-Grattoni, Anabel L.; Auguet, Josep M.; Pascual, Lydia; Vilà, Manel; Cortijo, Anunciación; Sánchez de la Torre, Manuel (Public Library of Science, 2018)

  Objectives Obstructive sleep apnea (OSA) is among the least studied risk factors for erectile dysfunction (ED). We aimed to determine ED prevalence in newly-diagnosed OSA patients, describe their main characteristics ...

• Exacerbations of chronic obstructive pulmonary disease: An analysis of the care process in a regional hospital emergency department 

  Abadías, María José; Yuguero Torres, Oriol; Bardés Robles, Ignasi; Casas-Méndez, Luis Fernando; Barbé Illa, Ferran; Batlle Garcia, Jordi de (Wolters Kluwer Health, Inc, 2018)

  To describe the characteristics of patients visiting a Hospital Emergency Department (HED) due to chronic obstructive pulmonary disease (COPD) exacerbation (AECOPD) and to evaluate their management. A cross-sectional ...

• Cytokeratin profile of basal cell carcinomas according to the degree of sun exposure and to the anatomical localization 

  García de la Fuente, María Reyes; Santacana Espasa, Maria; Valls Marsal, Joan; Vilardell, Felip; Fernández Armenteros, José Manuel; Pujol, Ramon; Garí Marsol, Eloi; Casanova i Seuma, Josep M. (Josep Manel) (Wolters Kluwer Health, Inc.International Society of Dermatopathology (ISDP), 2018)

  Basal cell carcinoma (BCC) seems to originate from ultraviolet light-induced mutations involving the bulge or the outer sheath of the hair follicle cells. However, the etiopathogenic mechanisms involved in the development ...

• Comparative analysis of predictive methods for early assessment of compliance with continuous positive airway pressure therapy 

  Rafael-Palou, Xavier; Turino, Cecilia; Steblin, Alexander; Sánchez de la Torre, Manuel; Barbé Illa, Ferran; Vargiu, Eloisa (BMC, 2018)

  Background: Patients suffering obstructive sleep apnea are mainly treated with continuous positive airway pressure (CPAP). Although it is a highly effective treatment, compliance with this therapy is problematic to achieve ...

• Improved adherence to Mediterranean Diet in adults with type 1 diabetes mellitus 

  Granado Casas, Minerva; Alcubierre Calvo, Núria; Martín, Mariona; Real, Jordi; Ramírez-Morros, Anna; Cuadrado, Maribel; Alonso, Núria; Falguera, Mireia; Hernández García, Marta; Aguilera, Eva; Lecube Torelló, Albert; Castelblanco Echavarría, Esmeralda; Puig-Domingo, Manuel; Mauricio Puente, Dídac (Springer, 2018-07-16)

  Purpose We aimed to assess food intake and adherence to the Mediterranean Diet in patients with T1D compared with nondiabetic individuals. Methods This was an observational, multicenter study in 262 T1D subjects and 254 ...

• Circulating angiotensin-converting enzyme 2 activity in patients with chronic kidney disease without previous history of cardiovascular disease 

  Anguiano, Lidia; Riera, Marta; Pascual, Julio; Valdivielso Revilla, José Manuel; Barrios, Clara; Betriu i Bars, M. Àngels; Mojal, Sergi; Fernández i Giráldez, Elvira; Soler, María José (Oxford University Press, 2015)

• Type 1 diabetic subjects with diabetic retinopathy show an unfavorable pattern of fat intake 

  Granado Casas, Minerva; Ramírez-Morros, Anna; Martín, Mariona; Real, Jordi; Alonso, Núria; Valldeperas, Xavier; Traveset Maeso, Alicia; Rubinat, Esther; Alcubierre Calvo, Núria; Hernández García, Marta; Puig-Domingo, Manuel; Lecube Torelló, Albert; Castelblanco Echavarría, Esmeralda; Mauricio Puente, Dídac (MDPI, 2018-08-29)

  Medical nutrition therapy is an important part of the management of type 1 diabetes mellitus (T1DM). Proper adherence to a healthy diet may have a favorable impact on diabetes management and its diabetic complications. Our ...

• The effect of depressive symptoms on cognition in patients with fibromyalgia 

  Gelonch Rosinach, Olga; Garolera i Freixa, Maite; Valls Marsal, Joan; Castellà, Gerard; Varela, Olalla; Rosselló Aubach, Lluís; Pifarré Paredero, Josep (Public Library of Science, 2018)

  Background Fibromyalgia (FM) patients frequently complain of cognitive problems, but it remains unclear whether these cognitive complaints can be attributed to a dysfunction of the central nervous system or if they can ...

• Association of serum phosphorus with subclinical atherosclerosis in chronic kidney disease. Sex makes a difference 

  Martín, Marisa; Valls Marsal, Joan; Betriu i Bars, M. Àngels; Fernández i Giráldez, Elvira; Valdivielso Revilla, José Manuel (Elsevier, 2015-02-28)

  Abstract BACKGROUND: Cardiovascular disease is the leading cause of mortality in chronic kidney disease (CKD). Serum phosphate has been associated to cardiovascular disease in the general population and this effect seems ...

• Markers of endothelial damage in patients with chronic kidney disease on hemodialysis 

  Carmona, Andrés; Agüera, Maria L.; Luna-Ruiz, Carlos; Buendía, Paula; Calleros-Basilio, Laura; García-Jerez, Andrea; Rodríguez-Puyol, Manuel; Arias, Manuel; Arias-Guillen, Marta; Arriba, Gabriel de; Ballarin, José; Bernis, Carmen; Fernández i Giráldez, Elvira; García-Rebollo, Sagrario; Mancha, Javier; Peso, Gloria del; Pérez, Estefanía; Poch, Esteban; Portolés, José M.; Rodríguez-Puyol, Diego; Sánchez-Villanueva, Rafael; Sarró, Felipe; Torres, Armando; Martín-Malo, Alejandro; Aljama, Pedro; Ramírez, Rafael; Carracedo, Júlia (American Physiological Society, 2017-04-01)

  Patients with Stage 5 chronic kidney disease who are on hemodialysis (HD) remain in a chronic inflammatory state, characterized by the accumulation of uremic toxins that induce endothelial damage and cardiovascular disease ...

• Increased Burden of Cerebral Small Vessel Disease in Patients With Type 2 Diabetes and Retinopathy 

  Sanahuja Montesinos, Jordi; Alonso, Núria; Diez, Javier; Ortega, Emilio; Rubinat, Esther; Traveset Maeso, Alicia; Alcubierre Calvo, Núria; Betriu i Bars, M. Àngels; Castelblanco Echavarría, Esmeralda; Hernández García, Marta; Purroy Garcia, Francisco; Arcidiacono, Maria V.; Jurjo Campo, Carmen; Fernández i Giráldez, Elvira; Puig-Domingo, Manuel; Groop, Per-Henrik; Mauricio Puente, Dídac (American Diabetes Association, 2016-06-08)

  OBJECTIVE We sought to examine the presence and severity of brain small vessel disease (SVD) in patients with type 2 diabetes and diabetic retinopathy (DR) compared with those without DR. RESEARCH DESIGN AND METHODS We ...

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