• The influence of an educational internet-based intervention in the beliefs and attitudes of primary care professionals on non-specific chronic low back pain: study protocol of a mixed methods approach 

  García-Martínez, Ester; Soler González, Jorge; Rubí Carnacea, Francesc; García-Martínez, Beatriz; Climent-Sanz, Carolina; Blanco Blanco, Joan; Valenzuela Pascual, Francesc (BMC, 2019)

  Background: Personal convictions in referral to pain cause misbeliefs in health professionals, which can influence patients who suffer from non-specific chronic low back pain. Likewise, health professionals’ beliefs affect ...

• Effects of Mediterranean Diet and Physical Activity on Pulmonary Function: A Cross-Sectional Analysis in the ILERVAS Project 

  Gutiérrez Carrasquilla, Liliana; Sánchez Peña, Enric; Hernández García, Marta; Polanco, Dinora; Salas-Salvadó, Jordi; Betriu i Bars, M. Àngels; Gaeta, Anna Michela; Carmona, Paola; Purroy Garcia, Francisco; Pamplona Gras, Reinald; Farràs, Cristina; López Cano, Carolina; Fernández i Giráldez, Elvira; Lecube Torelló, Albert (MDPI, 2019)

  A few studies showed that both adherence to Mediterranean diet (MedDiet) and physical activity practice have a positive impact on pulmonary function in subjects with lung disease. These associations are not well studied ...

• The influence of sleep apnea syndrome and intermittent hypoxia in carotid adventitial vasa vasorum 

  López Cano, Carolina; Rius, Ferran; Sánchez Peña, Enric; Gaeta, Anna Michela; Betriu i Bars, M. Àngels; Fernández i Giráldez, Elvira; Yeramian Hakim, Andree; Hernández García, Marta; Bueno Díez, Marta; Gutiérrez Carrasquilla, Liliana; Dalmases, Mireia; Lecube Torelló, Albert (Public Library of Science, 2019)

  Subjects with sleep apnea-hypopnea syndrome (SAHS) show an increased carotid intima-media thickness. However, no data exist about earlier markers of atheromatous disease, such as the proliferation and expansion of the ...

• Gremlin Regulates Tubular Epithelial to Mesenchymal Transition via VEGFR2: Potential Role in Renal Fibrosis 

  Marquez Exposito, Laura; Lavoz, Carolina; Rodrigues-Diez, Raul; Rayego Mateos, Sandra; Orejudo, Macarena; Cantero-Navarro, Elena; Ortiz, Alberto; Egido, Jesús; Selgas, Rafael; Mezzano, Sergio; Ruiz-Ortega, Marta (Frontiers Media, 2018)

  Chronic kidney disease (CKD) is emerging as an important health problem due to the increase number of CKD patients and the absence of an effective curative treatment. Gremlin has been proposed as a novel therapeutic target ...

• Regional Activation of Myosin II in Cancer Cells Drives Tumor Progression via a Secretory Cross-Talk with the Immune Microenvironment 

  Georgouli, Mirella; Herraiz, Cecilia; Crosas-Molist, Eva; Fanshawe, Bruce; Maiques Carlos, Oscar; Perdrix, Anna; Pandya, Pahini; Rodríguez Hernández, Irene; Ilieva, Kristina M.; Cantelli, Gaia; Karagiannis, Panagiotis; Mele, Silvia; Lam, Hoyin; Josephs, Debra H.; Matias-Guiu, Xavier; Martí Laborda, Rosa Ma.; Nestle, Frank O.; Orgaz, Jose L.; Malanchi, Ilaria; Fruhwirth, Gilbert O.; Karagiannis, Sophia N.; Sanz Moreno, Victoria (Elsevier, 2019)

  ROCK-Myosin II drives fast rounded-amoeboid migration in cancer cells during metastatic dissemination. Analysis of human melanoma biopsies revealed that amoeboid melanoma cells with high Myosin II activity are predominant ...

• Psoriasis, metabolic syndrome and cardiovascular risk factors. A population-based study. 

  Fernández Armenteros, José Manuel; Gómez Arbonés, Javier; Buti-Soler, M.; Betriu i Bars, M. Àngels; Sanmartín Novell, Verònica; Ortega Bravo, Marta; Martínez Alonso, Montserrat; Garí Marsol, Eloi; Portero Otín, Manuel; Santamaria-Babi, L.; Casanova i Seuma, Josep M. (Josep Manel) (Wiley, 2019)

  Abstract Background: Psoriasis is a very prevalent systemic chronic inflammatory disease. Major cardiovascular events are the main cause of mortality in these patients which suggests an association between psoriasis and ...

• Epigenetic Modification Mechanisms Involved in Inflammation and Fibrosis in Renal Pathology 

  Morgado-Pascual, José L.; Marchant, Vanessa; Dolade, Nuria; Rodrigues-Diez, Raul; Suarez-Alvarez, Beatriz; Kerr, Bredford; Valdivielso Revilla, José Manuel; Ruiz-Ortega, Marta; Rayego Mateos, Sandra (Hindawi Publishing Corporation, 2018)

  The growing incidence of obesity, hypertension, and diabetes, coupled with the aging of the population, is increasing the prevalence of renal diseases in our society. Chronic kidney disease (CKD) is characterized by ...

• Adiposity and risk of decline in glomerular filtration rate: meta-analysis of individual participant data in a global consortium 

  Chang, Alex R.; Grams, Morgan E.; Ballew, Shoshana H.; Bilo, Henk; Correa, Adolfo; Evans, Marie; Gutierrez, Orlando M.; Hosseinpanah, Farhad; Iseki, Kunitoshi; Kenealy, Timothy; Klein, Barbara; Kronenberg, Florian; Lee, Brian J.; Li, Yuanying; Navaneethan, Sankar D.; Roderick, Paul J; Valdivielso Revilla, José Manuel; Visseren, Frank L. J.; Zhang, Luxia; Gansevoort, Ron T.; Hallan, Stein I.; Levey, Andrew S.; Matsushita, Kunihiro; Shalev, Varda; Woodward, Mark (BMJ Publishing Group, 2019)

  OBJECTIVE To evaluate the associations between adiposity measures (body mass index, waist circumference, and waist-to-height ratio) with decline in glomerular filtration rate (GFR) and with all cause mortality. DESIGN ...

• The Spanish Society of Nephrology (SENEFRO) commentary to the Spain GBD 2016 report: Keeping chronic kidney disease out of sight of health authorities will only magnify the problem 

  Ortiz, Alberto; Sanchez-Niño, Maria-Dolores; Crespo-Barrio, Marta; De-Sequera-Ortiz, Patricia; Fernández i Giráldez, Elvira; García-Maset, Rafael; Macía-Heras, Manuel; Pérez Fontán, Miguel; Rodríguez, Mariano; Salgueira-Lazo, Mercedes; Sánchez Alvarez, Emilio; Santamaría-Olmo, Rafael; Simal-Blanco, Fernando; Pino, María Dolores del (Elsevier, 2019)

  The Global Burden of Disease (GBD) study measures the health of populations worldwide and by country on an annual basis and aims at helping guide public policy on health issues. The GBD estimates for Spain in 2016 and ...

• Role of Epidermal Growth Factor Receptor (EGFR) and Its Ligands in Kidney Inflammation and Damage 

  Rayego Mateos, Sandra; Rodrigues-Diez, Raul; Morgado-Pascual, José L.; Valentijn, Floris; Valdivielso Revilla, José Manuel; Goldschmeding, Roel; Ruiz-Ortega, Marta (Hindawi Publishing Corporation, 2018)

  Chronickidneydisease (CKD)ischaracterized bypersistent inflammationandprogressive fibrosis,ultimatelyleadingto end-stage renal disease. Although many studies have investigated the factors involved in the progressive deterioration ...

• Clinical experience with ferric carboxymaltose in the management of anemia in acute gastrointestinal bleeding 

  Ballester-Clau, Raquel; Torres Vicente, Gisela; Voltà-Pardo, Tania; López-Barroso, Laura; Cucala-Ramos, Mercedes; Reñé Espinet, Josep M.; Planella de Rubinat, Montse (Lippincott, Williams & Wilkins, 2019)

  Objective The aim of this study was to assess the efficacy and safety of intravenous ferric carboxymaltose (FCM) following hospitalization for acute gastrointestinal bleeding (AGIB) in the context of a restrictive transfusion ...

• Five-Year Risk of Stroke after TIA or Minor Ischemic Stroke 

  Amarenco, Pierre; Lavallée, Philippa C.; Tavares, Linsay Monteiro; Labreuche, Julien; Albers, Gregory W.; Abboud, Halim; Anticoli, Sabrina; Audebert, Heinrich; Bornstein, Natan M.; Caplan, Louis R.; Correia, Manuel; Donnan, Geoffrey A.; Ferro, José M.; Gongora-Rivera, Fernando; Heide, Wolfgang; Hennerici, Michael G.; Kelly, Peter J.; Král, Michal; Lin, Hsiu-Fen; Molina, Carlos; Park, Jong Moo; Purroy Garcia, Francisco; Rothwell, Peter M.; Segura, Tomas; Školoudík, David; Steg, Philippe Gabriel; Touboul, Pierre-Jean; Uchiyama, Shinichiro; Vicaut, Éric; Wang, Yongjun; Wong, Lawrence K.S (Massachusetts Medical Society, 2018)

  BACKGROUND After a transient ischemic attack (TIA) or minor stroke, the long-term risk of stroke and other vascular events is not well known. In this follow-up to a report on 1-year outcomes from a registry of TIA clinics ...

• Estudio observacional para analizar las pautas de tratamiento de la disnea irruptiva en pacientes con cáncer en la práctica clínica 

  Cabezón-Gutiérrez, Luis; Delgado-Mingorance, Ignacio; Nabal Vicuña, Maria; Jiménez-López, Antonio Javier; Cabezón-Álvarez, Ana; Soler-López, Begoña (Medwave Estudios Limitada, 2018-06-12)

  INTRODUCCIÓN: Siendo la disnea irruptiva un síntoma muy frecuente en los pacientes oncológicos, no existen recomendaciones precisas para su tratamiento. El objetivo principal del estudio fue analizar qué tratamientos se ...

• Serious Asthma Events with Fluticasone plus Salmeterol versus Fluticasone Alone 

  Stempel, David A.; Raphiou, Ibrahim H.; Kral, Kenneth M.; Yeakey, Anne M.; Emmett, Amanda H.; Prazma, Charlene M.; Buaron, Kathleen S.; Pascoe, Steven J.; Barbé Illa, Ferran (Massachusetts Medical Society, 2016)

  BACKGROUND The safe and appropriate use of long-acting beta-agonists (LABAs) for the treatment of asthma has been widely debated. In two large clinical trials, investigators found a potential risk of serious asthma-related ...

• Placebo-Controlled Trial of Oral Laquinimod for Multiple Sclerosis 

  Comi, Giancarlo; Jeffery, Douglas; Kappos, Ludwig; Montalban, Xavier; Boyko, Alexey; Rocca, Maria A.; Filippi, Massimo; Brieva Ruiz, Luis (Massachusetts Medical Society, 2012)

  BACKGROUND Two proof-of-concept clinical trials have provided evidence that laquinimod reduces disease activity in patients with relapsing–remitting multiple sclerosis. METHODS We conducted a randomized, double-blind, ...

• CPAP for Prevention of Cardiovascular Events in Obstructive Sleep Apnea 

  McEvoy, R. Doug; Antic, Nick A.; Heeley, Emma; Luo, Yuanming; Ou, Qiong; Zhang, Xilong; Mediano, Olga; Chen, Rui; Drager, Luciano; Liu, Zhihong; Chen, Guofang; Du, Baoliang; McArdle, Nigel; Mukherjee, Sutapa; Tripathi, Manjari; Billot, Laurent; Li, Qiang; Lorenzi-Filho, Geraldo; Barbé Illa, Ferran; Redline, Susan; Wang, Jiguang; Arima, Hisatomi; Neal, Bruce; White, David P.; Grunstein, Ron R.; Zhong, Nanshan; Anderson, Craig S. (Massachusetts Medical Society, 2016)

  Background Obstructive sleep apnea is associated with an increased risk of cardiovascular events; whether treatment with continuous positive airway pressure (CPAP) prevents major cardiovascular events is uncertain. Met ...

• Tiotropium versus Salmeterol for the Prevention of Exacerbations of COPD 

  Vogelmeier, Claus; Hederer, Bettina; Glaab, Thomas; Schmidt, Hendrik; Rutten-van Mölken, Maureen P.M.H.; Beeh, Kai M.; Fabbri, Leonardo M. (Massachusetts Medical Society, 2011)

  Background Treatment guidelines recommend the use of inhaled long-acting bronchodilators to alleviate symptoms and reduce the risk of exacerbations in patients with moderate-to-very-severe chronic obstructive pulmonary ...

• One-Year Risk of Stroke after Transient Ischemic Attack or Minor Stroke 

  Amarenco, Pierre; Lavallée, Philippa C.; Labreuche, Julien; Albers, Gregory W.; Bornstein, Natan M.; Canhão, Patrícia; Caplan, Louis R.; Donnan, Geoffrey A.; Ferro, José M.; Hennerici, Michael G.; Molina, Carlos; Rothwell, Peter M.; Sissani, Leila; Školoudík, David; Steg, Philippe Gabriel; Touboul, Pierre-Jean; Uchiyama, Shinichiro; Vicaut, Éric; Wong, Lawrence K.S; Purroy Garcia, Francisco (Massachusetts Medical Society, 2016)

  BACKGROUND Previous studies conducted between 1997 and 2003 estimated that the risk of stroke or an acute coronary syndrome was 12 to 20% during the first 3 months after a transient ischemic attack (TIA) or minor stroke. ...

• ¿Han llegado los millenials a la facultad de medicina? Perfil de personalidad de estudiantes de medicina 1999-2014 

  Amorós Galitó, Esther; Esquerda i Aresté, Montse; Agustí Farreny, Anna Maria; Kiskeri, Andrea; Prat Corominas, Joan; Viñas Salas, Joan; Pifarré Paredero, Josep (Elsevier, 2019)

  Introducción: La formación necesaria de un médico requiere no solo la adquisición de conocimientos y habilidades clínicas, sino también el desarrollo de actitudes y valores, características relacionadas con el perfil de ...

• Un año de registro de traumatismos graves en Cataluña. Análisis de los primeros resultados 

  Prat, Salvi; Domínguez-Sampedro, Pedro; Koo, Maylin; Colilles, Carme; Jiménez-Fábrega, Xavier; Espinosa, Lluis (Sociedad Española de Medicina de Urgencias y Emergencias (SEMES), 2014)

  Objetivo: Evaluar los resultados del primer año de implantación de un registro poblacional hospitalario de traumatismos graves en Cataluña (TraumCat). Método: Un total de 15 hospitales han recogido de forma prospectiva ...

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