• Diabetic and dyslipidaemic morbidly obese exhibit more liver alterations compared with healthy morbidly obese 

  Pardina, Eva; Ferrer, Roser; Rossell, Joana; Baena-Fustegueras, Juan A; Lecube Torelló, Albert; Fort, José Manuel; Caubet, Enric; González, Óscar; Vilallonga, Ramón; Vargas, Víctor; Balibrea, José María; Peinado-Onsurbe, Julia (Elsevier, 2016)

  Background & aims: To study the origin of fat excess in the livers of morbidly obese (MO) individuals, we analysed lipids and lipases in both plasma and liver and genes involved in lipid transport, or related with, in that ...

• Leading Factors for Weight Gain during COVID-19 Lockdown in a Spanish Population: A Cross-Sectional Study 

  Sánchez Peña, Enric; Lecube Torelló, Albert; Bellido, Diego; Monereo, Susana; Malagón, Maria Mar; Tinahones, Francisco José (MDPI, 2021)

  The increase in sedentary behaviors during the COVID-19-induced lockdown may have led to a significant weight gain. To investigate this hypothesis, a representative sample of the Spanish adult population comprising 1000 ...

• Resistencia a insulina en pequeños para la edad gestacional tratados con hormona de crecimiento. Estudio observacional 

  López Siguero, Juan P.; Martínez-Aedo, Maria J.; Bermúdez de la Vega, José A.; Bosch Muñoz, Jordi; Lechuga-Sancho, Alfonso M.; Fernandez-González, Ana; Villalobos, Triana (Pulso Ediciones, 2020-09)

  Background. In children born small for gestational age (SGA), the relationship between growth hormone (GH) treatment and insulin resistance [IR] has been investigated for a short-term period, being necessary a longer ...

• Informed Consent Procedure in Clinical Trials Promoted by the Hospital: Knowledge and Perceptions of Primary Care Physicians 

  Gómez Arbonés, Javier; Salazar-Alarcon, E.; Solanilla Puertolas, Montserrat; Ortega Bravo, Marta; Vallez-Valero, L.; Schoenenberger, Joan Antoni (SciTech Central, 2020-07-20)

  Objectives: To evaluate Primary Care Physician's (PCP) awareness degree concerning their patient's participation in Clinical Trials (CT) analyze the communication methods used and obtain physicians personal views. Methods: ...

• Clinico-epidemiological characteristics of men and women with a new diagnosis of chronic obstructive pulmonary disease: a database (SIDIAP) study 

  Montserrat i Capdevila, Josep; Marsal Mora, Josep Ramon; Ortega Bravo, Marta; Castañ, Maria Teresa; Alsedà Graells, Miquel; Barbé Illa, Ferran; Godoy i García, Pere (BioMed Central, 2021-01-28)

  Background: The risk of developing Chronic Obstructive Pulmonary Disease (COPD), the associated comorbidities and response to bronchodilators might differ in men and women. The objective of this study was to determine the ...

• Continuous positive airway pressure as treatment for systemic hypertension in people with obstructive sleep apnoea: randomised controlled trial 

  Durán-Cantolla, Joaquín; Aizpuru, Felipe; Montserrat, Josep Maria; Ballester, Eugeni; Terán, Joaquin; Aguirregomoscorta, Jose Ignacio; Gonzalez, Mónica; Lloberes, Patricia; Masa, Juan F.; Peña, Mónica de la; Carrizo, Santiago; Mayos, Mercè; Barbé Illa, Ferran (BMJ Publishing Group, 2010)

  Objective: To assess the effect of continuous positive airway pressure (CPAP) on 24 hour ambulatory blood pressure monitoring values in a large number of patients with untreated systemic hypertension of new onset and ...

• Peritoneal Dialysis Is an Independent Factor Associated to Lower Intima Media Thickness in Dialysis Patients Free From Previous Cardiovascular Disease 

  Borràs, Mercè; Cambray Carner, Serafí; Crespo Masip, Maria; Pérez Fontán, Miguel; Bozić Stanojević, Milica; Bermúdez López, Marcelino; Fernández i Giráldez, Elvira; Betriu i Bars, M. Àngels; Valdivielso Revilla, José Manuel (Frontiers Media, 2018)

• A Review of Clinical Studies and Practical Guide for the Administration of Triplet Chemotherapy Regimens with Bevacizumab in First-line Metastatic Colorectal Cancer 

  Loupakis, Fotios; Stein, Alexander; Ychou, Marc; Hermann, Frank; Salud Salvia, Maria Antonieta; Österlund, Pia (Springer, 2016)

  Colorectal cancer is the third most common cancer worldwide. A significant proportion of patients presents with unresectable metastatic disease or develops metachronous metastases following surgical resection of the primary ...

• Clinical Phenotypes and Comorbidity in European Sleep Apnoea Patients 

  Saaresranta, Tarja; Hedner, J.; Bonsignore, Maria R.; Riha, Renata L.; McNicholas, Walter T.; Penzel, Thomas; Anttalainen, Ulla; Kvamme, John Arthur; Pretl, Martin; Sliwinski, Pawel; Verbraecken, Johan; Grote, Ludger (Public Library of Science, 2016)

  Background: Clinical presentation phenotypes of obstructive sleep apnoea (OSA) and their association with comorbidity as well as impact on adherence to continuous positive airway pressure (CPAP) treatment have not been ...

• Biweekly cetuximab in combination with FOLFOX-4 in the first-line treatment of wild-type KRAS metastatic colorectal cancer: final results of a phase II, open-label, clinical trial (OPTIMIX-ACROSS Study) 

  Fernandez-Plana, Julen; Pericay, Carles; Quintero, Guillermo; Alonso, Vicente; Salud Salvia, Maria Antonieta; Mendez, Miguel; Salgado, Mercedes; Saigi, Eugeni; Cirera, Luis (BMC, 2014)

  Background: This phase II study aims to evaluate the efficacy and safety of biweekly cetuximab in combination with oxaliplatin, leucovorin, and fluorouracil (FOLFOX-4) as first-line treatment of metastatic wild-type KRAS ...

• The Diagnostic Value of Serum C-Reactive Protein for Identifying Pneumonia in Hospitalized Patients with Acute Respiratory Symptoms 

  Ruiz González, Agustín; Utrillo Montagut, Laia; Bielsa Martín, Silvia; Falguera i Sacrest, Miquel; Porcel Pérez, José Manuel (Hindawi, 2016)

  Background. The clinical diagnosis of pneumonia is sometimes difficult since chest radiographs are often indeterminate. In this study, we aimed to assess whether serum C-reactive protein (CRP) could assist in identifying ...

• Detection of Severe Obstructive Sleep Apnea through voice analysis 

  Solé-Casals, Jordi; Munteanu, Cristian; Capdevila Martín, Oriol; Barbé Illa, Ferran; Durán-Cantolla, Joaquín; Queipo, Carlos; Amilibia, Jose (Elsevier, 2014)

  This paper deals with the potential and limitations of using voice and speech processing to detect Obstructive Sleep Apnea (OSA). An extensive body of voice features has been extracted from patients who present various ...

• Costs and cost-efficacy analysis of the 2016 GESIDA/Spanish AIDS National Plan recommended guidelines for initial antiretroviral therapy in HIV-infected adults 

  Rivero, Antonio; Pérez-Molina, José Antonio; Blasco, Antonio Javier; Arribas, José Ramón; Crespo, Manuel; Domingo, Pere; Estrada, Vicente; Iribarren, José Antonio; Knobel, Hernando; Lázaro, Pablo; López Aldeguer, José; Lozano, Fernando; Moreno, Santiago; Palacios, Rosario; Pineda, Juan Antonio; Pulido, Federico; Rubio, Rafael; de la Torre, Javier; Tuset, Montserrat; Gatell, Josep M. (Elsevier, 2017)

  Introduction: GESIDA and the AIDS National Plan panel of experts suggest preferred (PR), alternative (AR) and other regimens (OR) for antiretroviral treatment (ART) as initial therapy in HIV-infected patients for 2016. ...

• Comparison of the King’s and MiToS staging systems for ALS 

  Fang, Ton; Al Khleifat, Ahmad; Stahl, Daniel R.; Lazo Latorre, Claudia; Murphy, Caroline; Licals, Uk-Mnd; Young, Carolyn; Shaw, Pamela J.; Leigh, P. Nigel; Al-Chalabi, Ammar (Taylor & Francis, 2017)

  Objective: To investigate and compare two ALS staging systems, King’s clinical staging and Milano-Torino (MiToS) functional staging, using data from the LiCALS phase III clinical trial (EudraCT 2008-006891-31). Methods: ...

• Prognostic impact of circulating plasma cells in patients with multiple myeloma: implications for plasma cell leukemia definition 

  Granell, Miquel; Calvo, Xavier; Garcia-Guiñón, Antoni; Escoda, Lourdes; Abella, Eugènia; Martínez, Clara Mª; Teixidó, Montserrat; Gimenez, Mª Teresa; Senín, Alicia; Sanz, Patricia; Campoy, Desirée; Vicent, Ana; Arenillas, Leonor; Rosiñol, Laura; Sierra, Jorge; Bladé, Joan; Fernández de Larrea, Carlos (Ferrata Storti FoundationEuropean Hematology Association, 2017)

  The presence of circulating plasma cells in patients with multiple myeloma is considered a marker for highly proliferative disease. In the study herein, the impact of circulating plasma cells assessed by cytology on survival ...

• Evaluación de la incidencia y tendencia de la enfermedad cerebrovascular en la región sanitaria de Lleida (España) en el periodo 2010-2014 

  Vena Martínez, Ana Belén; Cabré, Xavier; Piñol, R.; Molina Seguin, Jessica; Purroy Garcia, Francisco (Elsevier, 2020)

  Objetivo: Determinar la incidencia de la enfermedad cerebrovascular (ECV) y su tendencia en el área sanitaria de Lleida. Material y métodos: Estudio de cohortes de base poblacional que incluyó a toda la población del área ...

• Spanish People with Type 2 Diabetes Show an Improved Adherence to the Mediterranean Diet 

  Alcubierre Calvo, Núria; Granado Casas, Minerva; Real, Jordi; Perpiñán, Hèctor; Rubinat, Esther; Falguera, Mireia; Castelblanco Echavarría, Esmeralda; Franch-Nadal, Josep; Mauricio Puente, Dídac (MDPI, 2020)

  The aim of this study was to assess the dietary pattern (i.e., Mediterranean Diet (MedDiet) and healthy eating) in people with type 2 diabetes (T2D) compared with those without diabetes. In addition, we explored clinical ...

• Small-Molecule Inhibitors (SMIs) as an Effective Therapeutic Strategy for Endometrial Cancer 

  Megino-Luque, Cristina; Moiola, Cristian P.; Molins-Escuder, Clara; López-Gil, Carlos; Gil-Moreno, Antonio; Matias-Guiu, Xavier; Colás, Eva; Eritja Sánchez, Núria (MDPI, 2020-09-24)

  Endometrial cancer (EC) is the sixth most common cancer in women. A continued number of low-risk EC patients at diagnosis, as well as patients diagnosed with advanced-stage disease, will experience an aggressive disease. ...

• Autophagy in the physiological endometrium and cancer 

  Devis, Laura; Eritja Sánchez, Núria; Davis, Meredith L.; Matias-Guiu, Xavier; Llobet Navàs, David (Taylor & Francis, 2020-05-13)

  Autophagy is a highly conserved catabolic process and a major cellular pathway for the degradation of long-lived proteins and cytoplasmic organelles. An increasing body of evidence has unveiled autophagy as an indispensable ...

• Pleural diseases and COVID-19: ubi fumus, ibi ignis 

  Porcel Pérez, José Manuel (European Respiratory Society, 2020)

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