Browsing Articles publicats (Ciències Mèdiques Bàsiques) by Subject "Unfolded protein response"

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    • Mitochondrial Dysfunction and Oxidative and Endoplasmic Reticulum Stress in Argyrophilic Grain Disease 

      Ilieva, Ekaterina V.; Kichev, Anton Vladimirov; Naudí i Farré, Alba; Ferrer, Isidre; Pamplona Gras, Reinald; Portero Otín, Manuel (Oxford University Press, 2011)
      Argyrophilic grain disease (AGD) is characterized by the accumulation of hyperphosphorylated 4R tau in dendritic varicosities (i.e."grains") in neurons and pretangles in certain areas of the cerebral cortex and other brain ...

    • Voltage-gated calcium channel blockers deregulate macroautophagy in cardiomyocytes 

      Pushparaj, Charumathi; Das, Arindam; Purroy, Rosa; Nàger Grifo, Mireia; Herreros Danés, Judit; Pamplona Gras, Reinald; Cantí Nicolás, Carles (Elsevier, 2015)
      Voltage-gated calcium channel blockers are widely used for the management of cardiovascular diseases, however little is known about their effects on cardiac cells in vitro. We challenged neonatal ventricular cardiomyocytes ...