Now showing items 1-2 of 2

    • BCL-XL regulates TNF-α-mediated cell death independently of NF-κB, FLIP and IAPs 

      Gozzelino, Raffaella; Solé Serra, Carme; Llecha Cano, Núria; Segura Ginard, Miguel Francisco; Moubarak, Rana S.; Iglesias Guimarais, Victoria; Pérez García, María José; Reix, Stéphanie; Zhang, Jisheng; Badiola, Nahuai; Sanchis, Daniel; Rodríguez Álvarez, José; Trullas, Ramon; Yuste Mateos, Víctor J. (Víctor José); Comella i Carnicé, Joan Xavier (Springer Nature, 2008)
      Upon activation, tumor necrosis factor alpha (TNF-α) receptor can engage apoptotic or survival pathways. Inhibition of macromolecular synthesis is known to sensitize cells to TNF-α-induced cell death. It is believed that ...
    • Calmodulin Modulates Mitogen-Activated Protein Kinase Activation in Response to Membrane Depolarization in PC12 Cells 

      Egea Navarro, Joaquim; Espinet Mestre, Carme; Comella i Carnicé, Joan Xavier (Wiley, 1998)
      In the absence of neurotrophic factors, chronic depolarization of plasma membrane has been shown to maintain several populations of primary neurons in culture. We report that in the PC12 cell line, depolarization causes ...