Now showing items 1-3 of 3

    • Neuronal survival induced by neurotrophins requires calmodulin 

      Egea Navarro, Joaquim; Espinet Mestre, Carme; Soler i Tatché, Rosa Ma.; Dolcet Roca, Xavier; Yuste Mateos, Víctor J. (Víctor José); Encinas Martín, Mario; Iglesias Durán, Montserrat; Rocamora Ibars, Nativitat; Comella i Carnicé, Joan Xavier (Rockefeller University Press, 2001)
      It has been reported that phosphoinositide 3-kinase (PI 3-kinase) and its downstream target, protein kinase B (PKB), play a central role in the signaling of cell survival triggered by neurotrophins (NTs). In this report, ...
    • The death receptor antagonist FAIM promotes neurite outgrowth by a mechanism that depends on ERK and NF-κB signaling 

      Solé Serra, Carme; Dolcet Roca, Xavier; Segura Ginard, Miguel Francisco; Gutierrez, Humberto; Diaz Meco, Maria Teresa; Gozzelino, Raffaella; Sanchis, Daniel; Bayascas Ramírez, José Ramón; Gallego, Carme; Moscat, Jorge; Davies, Alun M.; Comella i Carnicé, Joan Xavier (Rockefeller University Press, 2004)
      Fas apoptosis inhibitory molecule (FAIM) is a protein identified as an antagonist of Fas-induced cell death. We show that FAIM overexpression fails to rescue neurons from trophic factor deprivation, but exerts a marked ...
    • β-catenin signalling in Glioblastoma multiforme and Glioma-initiating cells 

      Nàger Grifo, Mireia; Bhardwaj, Deepshikha; Cantí Nicolás, Carles; Medina Hernández, Loreta Mª; Nogués Bara, Pere; Herreros Danés, Judit (Hindawi Publishing Corporation, 2012)
      Glioblastoma multiforme (GBM) is a commonly occurring brain tumor with a poor prognosis. GBM can develop both “de novo” or evolve from a previous astrocytoma and is characterized by high proliferation and infiltration into ...