Browsing Articles publicats (Ciències Mèdiques Bàsiques) by Subject "Iron-overload"
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Major targets of iron-induced protein oxidative damage in frataxin-deficient yeasts are magnesium-binding proteins (Elsevier, 2008)Iron accumulation has been associated with several pathological conditions such as Friedreich ataxia. This human disorder is caused by decreased expression of frataxin. Iron-overload triggers oxidative stress, but the ...