Now showing items 1-3 of 3

    • Association of BST-2 Gene Variants With HIV Disease Progression Underscores the Role of BST-2 in HIV Type 1 Infection 

      Laplana Lafaja, Marina; Caruz, Antonio; Pineda, Juan Antonio; Puig, Teresa; Fibla Palazón, Joan (Oxford University Press, 2013-02-01)
      We tested bone marrow stromal cell antigen 2 (BST-2) gene variants rs3217318, a 19-base-pair insertion/deletion polymorphism in the promoter region, and rs10415893, a tag single-nucleotide polymorphism in the 3′ untranslated ...
    • Association of complement receptor 2 polymorphisms withinnate resistance to HIV-1 infection 

      Herrero, Rocío; Real, Luis M.; Rivero-Juárez, Antonio; Pineda, Juan Antonio; Camacho, Ángela; Macías, Juan; Laplana Lafaja, Marina; Konieczny, Piotr; Márquez, Francisco J.; Souto, Juan Carlos; Soria, José Manuel; Saulle, Irma; Lo Caputo, Sergio; Biasin, Mara; Rivero, Antonio; Fibla Palazón, Joan; Caruz, Antonio (Springer Nature, 2015-03)
      HIV-1 induces activation of complement through the classical and lectin pathways. However, the virus incorporates several membrane-bound or soluble regulators of complement activation (RCA) that inactivate complement. HIV-1 ...
    • Toll Like Receptor 2 promoter -196 to -174 deletion affects CD4 levels along HIV infection progression 

      Laplana Lafaja, Marina; Bravo, M. J.; Fernández-Fuertes, M.; Ruiz-García, C.; Alarcón-Martin, E.; Colmenero, J. D.; Caruz, Antonio; Fibla Palazón, Joan; Real, Luis M.; Royo Sánchez-Palencia, José Luis (Infectious Diseases Society of AmericaOxford University Press, 2020-06-09)
      TLR2 plays a key role in innate immune response recognizing molecular patterns expressed by pathogens. rs111200466 is a TLR2 promoter Insertion/Deletion polymorphism with contradictory data about its role in HIV-1 infection. ...