Now showing items 1-3 of 3

    • Smc5–Smc6 mediate DNA double-strand-break repair by promoting sister-chromatid recombination 

      De Piccoli, Giacomo; Cortes Ledesma, Felipe; Ira, Gregory; Torres Rosell, Jordi; Uhle, Stefan; Farmer, Sarah; Hwang, Ji-Young; Machin, Felix; Ceschia, Audrey; McAleenan, Alexandra; Cordon Preciado, Violeta; Clemente Blanco, Andrés; Vilella Mitjana, Felipe; Ullal, Pranav; Jarmuz, Adam; Leitao, Beatriz; Bressan, Debra; Dotiwala, Farokh; Papusha, Alma; Zhao, Xiaolan; Myung, Kyungjae; Haber, James E.; Aguilera, Andrés; Aragón, Luis (Nature, 2006)
      DNA double-strand breaks (DSB) can arise during DNA replication, or after exposure to DNA-damaging agents, and their correct repair is fundamental for cell survival and genomic stability. Here, we show that the ...
    • The Smc5/6 complex is required for dissolution of DNA-mediated sister chromatid linkages 

      Bermúdez López, Marcelino; Ceschia, Audrey; Piccoli, Giacomo De; Colomina i Gabarrella, Neus; Pasero, Philippe; Aragón, Luis; Torres Rosell, Jordi (Oxford University Press, 2010)
      Mitotic chromosome segregation requires the removal of physical connections between sister chromatids. In addition to cohesin and topological entrapments, sister chromatid separation can be prevented by the presence of ...
    • Use of the 16S-23S ribosomal genes spacer region for the molecular typing of sphingomonads 

      Tokajian, Sima; Almedawar, Seba; Hashwa, Fuad (NRC Research Press, 2008-08-31)
      The ability of sphingomonads in drinking water to cause community- and hospital-acquired opportunistic infections has raised the need to establish reproducible identification assays. In this study, a total of 129 isolates ...