Now showing items 1-15 of 15

    • 2-phenylethynesulphonamide (PFT-μ) enhances the anticancer effect of the novel hsp90 inhibitor NVP-AUY922 in melanoma, by reducing GSH levels 

      Yeramian Hakim, Andree; Veà Jódar, Àlvar; Benítez, Sandra; Ribera i Calvet, Joan; Domingo, Mónica; Santacana Espasa, Maria; Martínez Alonso, Montserrat; Maiques Carlos, Oscar; Valls Marsal, Joan; Dolcet Roca, Xavier; Vilella, Ramón; Cabiscol Català, Elisa; Matias-Guiu, Xavier; Marti, Rosa M. (Wiley online library, 2016)
      Heat shock proteins (HSPs), are molecular chaperones that assist the proper folding of nascent proteins. This study aims to evaluate the antitumour effects of the hsp90 inhibitor NVP-AUY922 in melanoma, both in vitro ...
    • A common copy-number variant within SIRPB1 correlates with human Out-of-Africa migration after genetic drift correction 

      Royo Sánchez-Palencia, José Luis; Valls Marsal, Joan; Acemel, Rafael D.; Gómez-Marin, Carlos; Pascual Pons, Mariona; Lupiañez, Arantxa; Gomez-Skarmeta, Jose Luis; Fibla Palazón, Joan (Public Library of Science, 2018)
      Previous reports have proposed that personality may have played a role on human Out-Of- Africa migration, pinpointing some genetic variants that were positively selected in the migrating populations. In this work, we ...
    • Association between Obstructive Sleep Apnea and Community-Acquired Pneumonia 

      Chiner, Eusebi; Llombart, Mónica; Valls Marsal, Joan; Pastor, Esther; Sancho-Chust, José; Luz Andreu, Ada; Sánchez de la Torre, Manuel; Barbé Illa, Ferran (Public Library of Science, 2016)
      Background: We hypothesized that obstructive sleep apnea (OSA) can predispose individuals to lower airway infections and community-acquired pneumonia (CAP) due to upper airway microaspiration. This study evaluated the ...
    • Biblio-MetReS: A bibliometric network reconstruction application and server 

      Usié Chimenos, Anabel; Karathia, Hiren; Teixidó Torrelles, Ivan; Valls Marsal, Joan; Faus i Torà, Xavier; Alves, Rui; Solsona Tehàs, Francesc (BioMed Central, 2011)
      Background: Reconstruction of genes and/or protein networks from automated analysis of the literature is one of the current targets of text mining in biomedical research. Some user-friendly tools already perform this ...
    • Cardiac troponin values in patients with acute coronary syndrome and sleep apnea: a pilot study 

      Sánchez de la Torre, Alicia; Soler, Xavier; Barbé Illa, Ferran; Florés, Marina; Maisel, Alan; Malhotra, Atul; Rué i Monné, Montserrat; Bertran, Sandra; Aldomá, Albina; Worner, Fernando; Valls Marsal, Joan; Lee, Chi-Hang; Turino, Cecilia; Galera, Estefanía; Batlle Garcia, Jordi de; Sánchez de la Torre, Manuel (Elsevier, 2018)
      Background: An analysis of cardiac injury markers in patients with OSA who sustain an episode of acute coronary syndrome (ACS) may contribute to a better understanding of the interactions and impact of OSA in subjects with ...
    • Characterization of cytoplasmic cyclin D1 as a marker of invasiveness in cancer 

      Pérez Fusté, Noel; Castelblanco Echavarría, Esmeralda; Felip, Isidre; Santacana Espasa, Maria; Fernández Hernández, Rita; Gatius Calderó, Sònia; Pedraza González, Neus; Pallares, Judit; Cemeli, Tània; Valls Marsal, Joan; Tarres, Marc; Ferrezuelo, Francisco; Dolcet Roca, Xavier; Matias-Guiu, Xavier; Garí Marsol, Eloi (Impact Journals, 2016)
      Cyclin D1 (Ccnd1) is a proto-oncogen amplified in many different cancers and nuclear accumulation of Ccnd1 is a characteristic of tumor cells. Ccnd1 activates the transcription of a large set of genes involved in cell ...
    • Concordance study between one-step nucleic acid amplification and morphologic techniques to detect lymph node metastasis in papillary carcinoma of the thyroid 

      del Carmen, Sofía; Gatius Calderó, Sònia; Franch Arcas, Guzmán; Baena-Fustegueras, Juan A; Gonzalez, Oscar; Zafon, Carles; Cuevas, Dolors; Valls Marsal, Joan; Pérez, Angustias; Martinez, Mercedes; Ros López, Susana; García Macías, Carmen; Iglesias, Carmela; Matias-Guiu, Xavier; de Álava, Enrique (Elsevier, 2016)
      Tumor resection in papillary thyroid carcinoma (PTC) is often accompanied by lymph node (LN) removal of the central and lateral cervical compartments. One-step nucleic acid amplification (OSNA) is a polymerase chain ...
    • Cytokeratin profile of basal cell carcinomas according to the degree of sun exposure and to the anatomical localization 

      García de la Fuente, María Reyes; Santacana Espasa, Maria; Valls Marsal, Joan; Vilardell, Felip; Fernández Armenteros, José Manuel; Pujol, Ramon; Garí Marsol, Eloi; Casanova i Seuma, Josep M. (Josep Manel) (Wolters Kluwer Health, Inc.International Society of Dermatopathology (ISDP), 2018)
      Basal cell carcinoma (BCC) seems to originate from ultraviolet light-induced mutations involving the bulge or the outer sheath of the hair follicle cells. However, the etiopathogenic mechanisms involved in the development ...
    • Effect of obstructive sleep apnoea on severity and short-term prognosis of acute coronary syndrome 

      Barbé Illa, Ferran; Sánchez de la Torre, Alicia; Abad, Jorge; Durán-Cantolla, Joaquín; Mediano, Olga; Amilibia, Jose; Masdeu, María José; Florés, Marina; Barceló Bennasar, Antònia; Peña, Mónica de la; Aldomá, Albina; Worner, Fernando; Valls Marsal, Joan; Castellà, Gerard; Sánchez de la Torre, Manuel (European Respiratory Society, 2015)
      The goal of this study was to evaluate the influence of obstructive sleep apnoea on the severity and short-term prognosis of patients admitted for acute coronary syndrome. Obstructive sleep apnoea was defined as an ...
    • Effect of Patient Sex on the Severity of Coronary Artery Disease in Patients with Newly Diagnosis of Obstructive Sleep Apnoea Admitted by an Acute Coronary Syndrome 

      Sánchez de la Torre, Alicia; Abad, Jorge; Durán-Cantolla, Joaquín; Mediano, Olga; Cabriada, Valentín; Masdeu, María José; Terán, Joaquin; Masa, Juan F.; Peña, Mónica de la; Aldomá, Albina; Worner, Fernando; Valls Marsal, Joan; Barbé Illa, Ferran; Sánchez de la Torre, Manuel (Public Library of Science, 2016)
      Background: The cardiovascular consequences of obstructive sleep apnoea (OSA) differ by sex. We hypothesized that sex influences the severity of acute coronary syndrome (ACS) in patients with OSA. OSA was defined as an ...
    • Immunohistochemical analysis of T-type calcium channels in acquired melanocytic nevi and melanoma 

      Maiques Carlos, Oscar; Macià Armengol, Anna; Moreno, Sara; Barceló Gómez, Carla; Santacana Espasa, Maria; Veà Jódar, Àlvar; Herreros Danés, Judit; Gatius Calderó, Sònia; Ortega Izquierdo, Maria Eugenia; Valls Marsal, Joan; Chen, Bo-Juen; Llovet Navàs, David; Matias-Guiu, Xavier; Cantí Nicolás, Carles; Martí Laborda, Rosa Ma. (Wiley Online Library, 2016-10-08)
      BACKGROUND AND OBJECTIVES: Cutaneous malignant melanoma arises from transformed melanocytes de novo or from congenital or acquired melanocytic nevi. We have recently reported that T-type Ca2+ channels (TTCs) are upregulated ...
    • Influencia del manguito de isquemia en la profilaxis antibiótica en prótesis total de rodilla 

      Prats Gispert, Laura; Valls Marsal, Joan; Ros Salvador, Joaquim; Jover, Alfredo; Pérez Villar, Ferran; Fernández Martínez, José Juan (Elsevier, 2015)
      Objetivo: Existe evidencia científica grado iv de la importancia que el antibiótico administradopreoperatoriamente tiene en la prevención de la infección protésica.Hay controversia en si la isquemia aplicada en la cirugía ...
    • Optimal protocol for PTEN immunostaining; role of analytical and preanalytical variables in PTEN staining in normal and neoplastic endometrial, breast, and prostatic tissues 

      Maiques Carlos, Oscar; Santacana Espasa, Maria; Valls Marsal, Joan; Pallares, Judit; Mirantes Barbeito, Cristina; Gatius Calderó, Sònia; García Dios, Diego Andrés; Amant, Frederic; Pedersen, Hans Christian; Dolcet Roca, Xavier; Matias-Guiu, Xavier (Elsevier, 2014)
      In some tumors, phosphatase and tensin homolog (PTEN) inactivation may have prognostic importance and predictive value for targeted therapies. Immunohistochemistry (IHC) may be an effective method to demonstrate PTEN loss. ...
    • Preclinical carotid atherosclerosis in patients with latent autoimmune diabetes in adults (LADA), type 2 diabetes and classical type 1 diabetes 

      Hernández García, Marta; López Cano, Carolina; Real, Jordi; Valls Marsal, Joan; Ortega, Emilio; Vázquez, Federico; Rubinat, Esther; Granado Casas, Minerva; Alonso, Núria; Molí, Teresa; Betriu i Bars, M. Àngels; Lecube Torelló, Albert; Fernández i Giráldez, Elvira; David Leslie, Richard; Mauricio Puente, Dídac (BioMed Central, 2017)
      LADA is probably the most prevalent form of autoimmune diabetes. Nevertheless, there are few data about cardiovascular disease in this group of patients. The aim of this study was to investigate the frequency of carotid ...
    • Relationship of the adherence to the Mediterranean diet with health-related quality of life and treatment satisfaction in patients with type 2 diabetes mellitus: a post-hoc analysis of a cross-sectional study 

      Alcubierre Calvo, Núria; Martínez Alonso, Montserrat; Valls Marsal, Joan; Rubinat, Esther; Traveset Maeso, Alicia; Hernandez, Marta; Martínez González, María Dolores; Granado Casas, Minerva; Jurjo Campo, Carmen; Vioque, Jesus; Navarrete Muñoz, Eva María; Mauricio Puente, Dídac (BioMed Central, 2016)
      Objective: The main aim of this study was to assess the association between adherence to the traditional Mediterranean diet (MedDiet) and health-related quality of life (HRQoL) and treatment satisfaction in patients ...